PIK3CA c.59T>G ;(p.I20S)

Variant ID: 3-178916672-T-G

NM_006218.2(PIK3CA):c.59T>G;(p.I20S)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Proteostasis, oxidative stress and aging.

Redox Biology
Korovila, Ioanna I; Hugo, Martín M; Castro, José Pedro JP; Weber, Daniela D; Höhn, Annika A; Grune, Tilman T; Jung, Tobias T
Publication Date: 2017-10

Variant appearance in text: PI3K: i20S
PubMed Link: 28763764
Variant Present in the following documents:
  • Main text
  • main.pdf
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Carfilzomib boosted combination therapy for relapsed multiple myeloma.

Oncotargets And Therapy
Steiner, Raphael E RE; Manasanch, Elisabet E EE
Publication Date: 2017

Variant appearance in text: PI3K: i20S
PubMed Link: 28243125
Variant Present in the following documents:
  • Main text
View BVdb publication page



Redox control of protein degradation.

Redox Biology
Pajares, Marta M; Jiménez-Moreno, Natalia N; Dias, Irundika H K IHK; Debelec, Bilge B; Vucetic, Milica M; Fladmark, Kari E KE; Basaga, Huveyda H; Ribaric, Samo S; Milisav, Irina I; Cuadrado, Antonio A
Publication Date: 2015-12

Variant appearance in text: PI3K: i20S
PubMed Link: 26381917
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Proteasome inhibitors - molecular basis and current perspectives in multiple myeloma.

Journal Of Cellular And Molecular Medicine
Kubiczkova, Lenka L; Pour, Ludek L; Sedlarikova, Lenka L; Hajek, Roman R; Sevcikova, Sabina S
Publication Date: 2014-06

Variant appearance in text: PI3K: i20S
PubMed Link: 24712303
Variant Present in the following documents:
  • Main text
  • jcmm0018-0947.pdf
View BVdb publication page



Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models.

Oncogenesis
Crawford, L J LJ; Chan, E T ET; Aujay, M M; Holyoake, T L TL; Melo, J V JV; Jorgensen, H G HG; Suresh, S S; Walker, B B; Irvine, A E AE
Publication Date: 2014-03-03

Variant appearance in text: PI3K: i20S
PubMed Link: 24590311
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel treatment options for Waldenström macroglobulinemia.

Clinical Lymphoma, Myeloma & Leukemia
Leblebjian, Houry H; Agarwal, Amit A; Ghobrial, Irene I
Publication Date: 2013-09

Variant appearance in text: PI3K: i20S
PubMed Link: 24290218
Variant Present in the following documents:
  • Main text
View BVdb publication page



The resistance mechanisms of proteasome inhibitor bortezomib.

Biomarker Research
Lü, Shuqing S; Wang, Jianmin J
Publication Date: 2013-03-01

Variant appearance in text: PI3K: i20S
PubMed Link: 24252210
Variant Present in the following documents:
  • Main text
  • 2050-7771-1-13.pdf
View BVdb publication page



The proteasome inhibitor carfilzomib functions independently of p53 to induce cytotoxicity and an atypical NF-κB response in chronic lymphocytic leukemia cells.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gupta, Sneha V SV; Hertlein, Erin E; Lu, Yanhui Y; Sass, Ellen J EJ; Lapalombella, Rosa R; Chen, Timothy L TL; Davis, Melanie E ME; Woyach, Jennifer A JA; Lehman, Amy A; Jarjoura, David D; Byrd, John C JC; Lucas, David M DM
Publication Date: 2013-05-01

Variant appearance in text: PI3K: i20S
PubMed Link: 23515408
Variant Present in the following documents:
  • Main text
View BVdb publication page