PIK3CA c.109C>T ;(p.L37F)

Variant ID: 3-178916722-C-T

NM_006218.2(PIK3CA):c.109C>T;(p.L37F)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


The multiple roles of nsp6 in the molecular pathogenesis of SARS-CoV-2.

Antiviral Research
Bills, Cody C; Xie, Xuping X; Shi, Pei-Yong PY
Publication Date: 2023-03-30

Variant appearance in text: PI3K: L37F
PubMed Link: 37003304
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: PIK3CA: 109C>T; L37F
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 2
  • Table_2.xlsx, sheet 3
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: PIK3CA: 109C>T
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: PIK3CA: 109C>T; L37F
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: PIK3CA: 109C>T; L37F
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: PIK3CA: 109C>T; L37F
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Stepwise addition of genetic changes correlated with histological change from "well-differentiated" to "sarcomatoid" phenotypes: a case report.

Bmc Cancer
Goto, Taichiro T; Hirotsu, Yosuke Y; Mochizuki, Hitoshi H; Nakagomi, Takahiro T; Oyama, Toshio T; Amemiya, Kenji K; Omata, Masao M
Publication Date: 2017-01-19

Variant appearance in text: PIK3CA: L37F
PubMed Link: 28103823
Variant Present in the following documents:
  • 12885_2017_Article_3059.pdf
  • 12885_2017_3059_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations.

Oncotarget
Riveiro, Maria E ME; Astorgues-Xerri, Lucile L; Vazquez, Ramiro R; Frapolli, Roberta R; Kwee, Ivo I; Rinaldi, Andrea A; Odore, Elodie E; Rezai, Keyvan K; Bekradda, Mohamed M; Inghirami, Giorgio G; D'Incalci, Maurizio M; Noel, Kay K; Cvitkovic, Esteban E; Raymond, Eric E; Bertoni, Francesco F
Publication Date: 2016-12-20

Variant appearance in text: PIK3CA: 109C>T
PubMed Link: 27835869
Variant Present in the following documents:
  • oncotarget-07-84675-s001.pdf
View BVdb publication page



LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.

British Journal Of Cancer
Mahoney, C L CL; Choudhury, B B; Davies, H H; Edkins, S S; Greenman, C C; Haaften, G van Gv; Mironenko, T T; Santarius, T T; Stevens, C C; Stratton, M R MR; Futreal, P A PA
Publication Date: 2009-01-27

Variant appearance in text: PIK3CA: 109C>T
PubMed Link: 19165201
Variant Present in the following documents:
  • Main text
View BVdb publication page