Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
Neuro-Oncology
Zhang, Yalan Y; Lucas, Calixto-Hope G CG; Young, Jacob S JS; Morshed, Ramin A RA; McCoy, Lucie L; Oberheim Bush, Nancy Ann NA; Taylor, Jennie W JW; Daras, Mariza M; Butowski, Nicholas A NA; Villanueva-Meyer, Javier E JE; Cha, Soonmee S; Wrensch, Margaret M; Wiencke, John K JK; Lee, Julieann C JC; Pekmezci, Melike M; Phillips, Joanna J JJ; Perry, Arie A; Bollen, Andrew W AW; Aghi, Manish K MK; Theodosopoulos, Philip P; Chang, Edward F EF; Hervey-Jumper, Shawn L SL; Berger, Mitchel S MS; Clarke, Jennifer L JL; Chang, Susan M SM; Molinaro, Annette M AM; Solomon, David A DA
Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.
Nature Communications
Nikbakht, Hamid H; Panditharatna, Eshini E; Mikael, Leonie G LG; Li, Rui R; Gayden, Tenzin T; Osmond, Matthew M; Ho, Cheng-Ying CY; Kambhampati, Madhuri M; Hwang, Eugene I EI; Faury, Damien D; Siu, Alan A; Papillon-Cavanagh, Simon S; Bechet, Denise D; Ligon, Keith L KL; Ellezam, Benjamin B; Ingram, Wendy J WJ; Stinson, Caedyn C; Moore, Andrew S AS; Warren, Katherine E KE; Karamchandani, Jason J; Packer, Roger J RJ; Jabado, Nada N; Majewski, Jacek J; Nazarian, Javad J
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer.
Investigational New Drugs
Rodón, Jordi J; Carducci, Michael M; Sepulveda-Sánchez, Juan M JM; Azaro, Analía A; Calvo, Emiliano E; Seoane, Joan J; Braña, Irene I; Sicart, Elisabet E; Gueorguieva, Ivelina I; Cleverly, Ann A; Pillay, N Sokalingum NS; Desaiah, Durisala D; Estrem, Shawn T ST; Paz-Ares, Luis L; Holdhoff, Matthias M; Blakeley, Jaishri J; Lahn, Michael M MM; Baselga, Jose J
Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas.
Bmc Cancer
Tone, Alicia A AA; McConechy, Melissa K MK; Yang, Winnie W; Ding, Jiarui J; Yip, Stephen S; Kong, Esther E; Wong, Kwong-Kwok KK; Gershenson, David M DM; Mackay, Helen H; Shah, Sohrab S; Gilks, Blake B; Tinker, Anna V AV; Clarke, Blaise B; McAlpine, Jessica N JN; Huntsman, David D
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
Nature Genetics
Wu, Gang G; Diaz, Alexander K AK; Paugh, Barbara S BS; Rankin, Sherri L SL; Ju, Bensheng B; Li, Yongjin Y; Zhu, Xiaoyan X; Qu, Chunxu C; Chen, Xiang X; Zhang, Junyuan J; Easton, John J; Edmonson, Michael M; Ma, Xiaotu X; Lu, Charles C; Nagahawatte, Panduka P; Hedlund, Erin E; Rusch, Michael M; Pounds, Stanley S; Lin, Tong T; Onar-Thomas, Arzu A; Huether, Robert R; Kriwacki, Richard R; Parker, Matthew M; Gupta, Pankaj P; Becksfort, Jared J; Wei, Lei L; Mulder, Heather L HL; Boggs, Kristy K; Vadodaria, Bhavin B; Yergeau, Donald D; Russell, Jake C JC; Ochoa, Kerri K; Fulton, Robert S RS; Fulton, Lucinda L LL; Jones, Chris C; Boop, Frederick A FA; Broniscer, Alberto A; Wetmore, Cynthia C; Gajjar, Amar A; Ding, Li L; Mardis, Elaine R ER; Wilson, Richard K RK; Taylor, Michael R MR; Downing, James R JR; Ellison, David W DW; Zhang, Jinghui J; Baker, Suzanne J SJ
Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Hafner, Christian C; Toll, Agustí A; Fernández-Casado, Alejandro A; Earl, Julie J; Marqués, Miriam M; Acquadro, Francesco F; Méndez-Pertuz, Marinela M; Urioste, Miguel M; Malats, Núria N; Burns, Julie E JE; Knowles, Margaret A MA; Cigudosa, Juan C JC; Hartmann, Arndt A; Vogt, Thomas T; Landthaler, Michael M; Pujol, Ramón M RM; Real, Francisco X FX