Publications:

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: PIK3CA: Arg141Cys

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

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Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies.

The Journal Of Pathology

Cyrta, Joanna J; Prandi, Davide D; Arora, Arshi A; Hovelson, Daniel H DH; Sboner, Andrea A; Rodriguez, Antonio A; Fedrizzi, Tarcisio T; Beltran, Himisha H; Robinson, Dan R DR; Gopalan, Anuradha A; True, Lawrence L; Nelson, Peter S PS; Robinson, Brian D BD; Mosquera, Juan Miguel JM; Tomlins, Scott A SA; Shen, Ronglai R; Demichelis, Francesca F; Rubin, Mark A MA

Publication Date: 2022-07

Variant appearance in text: PIK3CA: R141C

PubMed Link: 35220606

Variant Present in the following documents:

• PATH-257-274-s001.xlsx, sheet 7

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Integration of Tumor Heterogeneity for Recurrence Prediction in Patients with Esophageal Squamous Cell Cancer.

Cancers

Mai, Zihang Z; Liu, Qianwen Q; Wang, Xinye X; Xie, Jiaxin J; Yuan, Jianye J; Zhong, Jian J; Fang, Shuogui S; Xie, Xiuying X; Yang, Hong H; Wen, Jing J; Fu, Jianhua J

Publication Date: 2021-12-02

Variant appearance in text: PIK3CA: R141C

PubMed Link: 34885197

Variant Present in the following documents:

• Main text
• cancers-13-06084.pdf

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Integration of Tumor Heterogeneity for Recurrence Prediction in Patients with Esophageal Squamous Cell Cancer.

Cancers

Mai, Zihang Z; Liu, Qianwen Q; Wang, Xinye X; Xie, Jiaxin J; Yuan, Jianye J; Zhong, Jian J; Fang, Shuogui S; Xie, Xiuying X; Yang, Hong H; Wen, Jing J; Fu, Jianhua J

Publication Date: 2021-12-02

Variant appearance in text: PIK3CA: R141C

PubMed Link: 34885197

Variant Present in the following documents:

• Main text
• cancers-13-06084.pdf

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Genomic Landscape of Head and Neck Squamous Cell Carcinoma Across Different Anatomic Sites in Chinese Population.

Frontiers In Genetics

Ju, Yunhe Y; Wu, Xingrao X; Wang, Huizhen H; Li, Bin B; Long, Qing Q; Zhang, Dadong D; Chen, Hao H; Xiao, Nianqing N; Li, Fugen F; Zhang, Shiwen S; Yang, Shenggang S

Publication Date: 2021

Variant appearance in text: PIK3CA: R141C

PubMed Link: 34194478

Variant Present in the following documents:

• Data_Sheet_1.xlsx, sheet 6

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A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology.

Acta Neuropathologica Communications

Lorenz, Julia J; Rothhammer-Hampl, Tanja T; Zoubaa, Saida S; Bumes, Elisabeth E; Pukrop, Tobias T; Kölbl, Oliver O; Corbacioglu, Selim S; Schmidt, Nils O NO; Proescholdt, Martin M; Hau, Peter P; Riemenschneider, Markus J MJ

Publication Date: 2020-08-05

Variant appearance in text: PIK3CA: R141C

PubMed Link: 32758285

Variant Present in the following documents:

• 40478_2020_1000_MOESM3_ESM.xlsx, sheet 1

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A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling.

Cell Research

Qian, Junbin J; Olbrecht, Siel S; Boeckx, Bram B; Vos, Hanne H; Laoui, Damya D; Etlioglu, Emre E; Wauters, Els E; Pomella, Valentina V; Verbandt, Sara S; Busschaert, Pieter P; Bassez, Ayse A; Franken, Amelie A; Bempt, Marlies Vanden MV; Xiong, Jieyi J; Weynand, Birgit B; van Herck, Yannick Y; Antoranz, Asier A; Bosisio, Francesca Maria FM; Thienpont, Bernard B; Floris, Giuseppe G; Vergote, Ignace I; Smeets, Ann A; Tejpar, Sabine S; Lambrechts, Diether D

Publication Date: 2020-09

Variant appearance in text: PIK3CA: R141C

PubMed Link: 32561858

Variant Present in the following documents:

• 41422_2020_355_MOESM15_ESM.xlsx, sheet 1

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Patient-Derived Orthotopic Xenograft Models of Pediatric Brain Tumors: In a Mature Phase or Still in Its Infancy?

Frontiers In Oncology

Hermans, Eva E; Hulleman, Esther E

Publication Date: 2019

Variant appearance in text: PIK3CA: R141C

PubMed Link: 31970083

Variant Present in the following documents:

• Main text

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The Discordance of Gene Mutations between Circulating Tumor Cells and Primary/Metastatic Tumor.

Molecular Therapy Oncolytics

Wang, Qi Q; Zhao, Lanbo L; Han, Lu L; Tuo, Xiaoqian X; Ma, Sijia S; Wang, Yiran Y; Feng, Xue X; Liang, Dongxin D; Sun, Chao C; Wang, Qing Q; Song, Qing Q; Li, Qiling Q

Publication Date: 2019-12-20

Variant appearance in text: PIK3CA: R141C

PubMed Link: 31650022

Variant Present in the following documents:

• Main text
• main.pdf
• mmc3.xls, sheet 1

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POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.

Journal Of The American Heart Association

Calvete, Oriol O; Garcia-Pavia, Pablo P; Domínguez, Fernando F; Mosteiro, Lluc L; Pérez-Cabornero, Lucía L; Cantalapiedra, Diego D; Zorio, Esther E; Ramón Y Cajal, Teresa T; Crespo-Leiro, Maria G MG; Teulé, Álex Á; Lázaro, Conxi C; Morente, Manuel M MM; Urioste, Miguel M; Benitez, Javier J

Publication Date: 2019-09-17

Variant appearance in text: PIK3CA: Arg141Cys

PubMed Link: 31510873

Variant Present in the following documents:

• JAH3-8-e012875-s001.pdf
• JAH3-8-e012875.pdf

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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications

Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML

Publication Date: 2017-02-10

Variant appearance in text: PIK3CA: R141C

PubMed Link: 28186126

Variant Present in the following documents:

• ncomms14262-s5.xlsx, sheet 2

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Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.

Nature Communications

Nikbakht, Hamid H; Panditharatna, Eshini E; Mikael, Leonie G LG; Li, Rui R; Gayden, Tenzin T; Osmond, Matthew M; Ho, Cheng-Ying CY; Kambhampati, Madhuri M; Hwang, Eugene I EI; Faury, Damien D; Siu, Alan A; Papillon-Cavanagh, Simon S; Bechet, Denise D; Ligon, Keith L KL; Ellezam, Benjamin B; Ingram, Wendy J WJ; Stinson, Caedyn C; Moore, Andrew S AS; Warren, Katherine E KE; Karamchandani, Jason J; Packer, Roger J RJ; Jabado, Nada N; Majewski, Jacek J; Nazarian, Javad J

Publication Date: 2016-04-06

Variant appearance in text: PIK3CA: R141C

PubMed Link: 27048880

Variant Present in the following documents:

• ncomms11185-s1.pdf

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An Immunohistochemical Algorithm for Ovarian Carcinoma Typing.

International Journal Of Gynecological Pathology : Official Journal Of The International Society Of Gynecological Pathologists

Köbel, Martin M; Rahimi, Kurosh K; Rambau, Peter F PF; Naugler, Christopher C; Le Page, Cécile C; Meunier, Liliane L; de Ladurantaye, Manon M; Lee, Sandra S; Leung, Samuel S; Goode, Ellen L EL; Ramus, Susan J SJ; Carlson, Joseph W JW; Li, Xiaodong X; Ewanowich, Carol A CA; Kelemen, Linda E LE; Vanderhyden, Barbara B; Provencher, Diane D; Huntsman, David D; Lee, Cheng-Han CH; Gilks, C Blake CB; Mes Masson, Anne-Marie AM

Publication Date: 2016-09

Variant appearance in text: PIK3CA: R141C

PubMed Link: 26974996

Variant Present in the following documents:

• pgp-35-430-s003.xlsx, sheet 1

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Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One

Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M

Publication Date: 2015

Variant appearance in text: PIK3CA: R141C

PubMed Link: 26010451

Variant Present in the following documents:

• pone.0127146.s014.xlsx, sheet 3

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Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes.

Nature Communications

Dhanasekaran, Saravana M SM; Balbin, O Alejandro OA; Chen, Guoan G; Nadal, Ernest E; Kalyana-Sundaram, Shanker S; Pan, Jincheng J; Veeneman, Brendan B; Cao, Xuhong X; Malik, Rohit R; Vats, Pankaj P; Wang, Rui R; Huang, Stephanie S; Zhong, Jinjie J; Jing, Xiaojun X; Iyer, Matthew M; Wu, Yi-Mi YM; Harms, Paul W PW; Lin, Jules J; Reddy, Rishindra R; Brennan, Christine C; Palanisamy, Nallasivam N; Chang, Andrew C AC; Truini, Anna A; Truini, Mauro M; Robinson, Dan R DR; Beer, David G DG; Chinnaiyan, Arul M AM

Publication Date: 2014-12-22

Variant appearance in text: PIK3CA: R141C

PubMed Link: 25531467

Variant Present in the following documents:

• Main text

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Evaluation of ultra-deep targeted sequencing for personalized breast cancer care.

Breast Cancer Research : Bcr

Harismendy, Olivier O; Schwab, Richard B RB; Alakus, Hakan H; Yost, Shawn E SE; Matsui, Hiroko H; Hasteh, Farnaz F; Wallace, Anne M AM; Park, Hannah L HL; Madlensky, Lisa L; Parker, Barbara B; Carpenter, Philip M PM; Jepsen, Kristen K; Anton-Culver, Hoda H; Frazer, Kelly A KA

Publication Date: 2013-12-10

Variant appearance in text: PIK3CA: R141C

PubMed Link: 24326041

Variant Present in the following documents:

• bcr3584-S1.pdf

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Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma.

Oncotarget

Kannan, Kasthuri K; Inagaki, Akiko A; Silber, Joachim J; Gorovets, Daniel D; Zhang, Jianan J; Kastenhuber, Edward R ER; Heguy, Adriana A; Petrini, John H JH; Chan, Timothy A TA; Huse, Jason T JT

Publication Date: 2012-10

Variant appearance in text: PIK3CA: R141C

PubMed Link: 23104868

Variant Present in the following documents:

• oncotarget-03-1194.pdf

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Nature

Barretina, Jordi J; Caponigro, Giordano G; Stransky, Nicolas N; Venkatesan, Kavitha K; Margolin, Adam A AA; Kim, Sungjoon S; Wilson, Christopher J CJ; Lehár, Joseph J; Kryukov, Gregory V GV; Sonkin, Dmitriy D; Reddy, Anupama A; Liu, Manway M; Murray, Lauren L; Berger, Michael F MF; Monahan, John E JE; Morais, Paula P; Meltzer, Jodi J; Korejwa, Adam A; Jané-Valbuena, Judit J; Mapa, Felipa A FA; Thibault, Joseph J; Bric-Furlong, Eva E; Raman, Pichai P; Shipway, Aaron A; Engels, Ingo H IH; Cheng, Jill J; Yu, Guoying K GK; Yu, Jianjun J; Aspesi, Peter P; de Silva, Melanie M; Jagtap, Kalpana K; Jones, Michael D MD; Wang, Li L; Hatton, Charles C; Palescandolo, Emanuele E; Gupta, Supriya S; Mahan, Scott S; Sougnez, Carrie C; Onofrio, Robert C RC; Liefeld, Ted T; MacConaill, Laura L; Winckler, Wendy W; Reich, Michael M; Li, Nanxin N; Mesirov, Jill P JP; Gabriel, Stacey B SB; Getz, Gad G; Ardlie, Kristin K; Chan, Vivien V; Myer, Vic E VE; Weber, Barbara L BL; Porter, Jeff J; Warmuth, Markus M; Finan, Peter P; Harris, Jennifer L JL; Meyerson, Matthew M; Golub, Todd R TR; Morrissey, Michael P MP; Sellers, William R WR; Schlegel, Robert R; Garraway, Levi A LA

Publication Date: 2012-03-28

Variant appearance in text: PIK3CA: R141C

PubMed Link: 22460905

Variant Present in the following documents:

• NIHMS361223-supplement-4.xlsx, sheet 3

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