Publications:

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Class IA PI3K regulatory subunits: p110-independent roles and structures.

Biochemical Society Transactions

Fox, Millie M; Mott, Helen R HR; Owen, Darerca D

Publication Date: 2020-08-28

Variant appearance in text: PI3K: R274A

PubMed Link: 32677674

Variant Present in the following documents:

• Main text
• BST-48-1397.pdf

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Impact of p85α Alterations in Cancer.

Biomolecules

Marshall, Jeremy D S JDS; Whitecross, Dielle E DE; Mellor, Paul P; Anderson, Deborah H DH

Publication Date: 2019-01-15

Variant appearance in text: PI3K: R274A

PubMed Link: 30650664

Variant Present in the following documents:

• Main text
• biomolecules-09-00029.pdf

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Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation.

Scientific Reports

Mellor, Paul P; Marshall, Jeremy D S JDS; Ruan, Xuan X; Whitecross, Dielle E DE; Ross, Rebecca L RL; Knowles, Margaret A MA; Moore, Stanley A SA; Anderson, Deborah H DH

Publication Date: 2018-05-08

Variant appearance in text: PI3K: R274A

PubMed Link: 29740032

Variant Present in the following documents:

• Main text
• 41598_2018_Article_25487.pdf

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Identification of mutations in distinct regions of p85 alpha in urothelial cancer.

Plos One

Ross, Rebecca L RL; Burns, Julie E JE; Taylor, Claire F CF; Mellor, Paul P; Anderson, Deborah H DH; Knowles, Margaret A MA

Publication Date: 2013

Variant appearance in text: PI3K: R274A

PubMed Link: 24367658

Variant Present in the following documents:

• Main text
• pone.0084411.pdf

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Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Chagpar, Ryaz B RB; Links, Philip H PH; Pastor, M Chris MC; Furber, Levi A LA; Hawrysh, Andrea D AD; Chamberlain, M Dean MD; Anderson, Deborah H DH

Publication Date: 2010-03-23

Variant appearance in text: PI3K: R274A

PubMed Link: 20212113

Variant Present in the following documents:

• Main text

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Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria.

Nature Immunology

Tiwari, Sangeeta S; Choi, Han-Pil HP; Matsuzawa, Takeshi T; Pypaert, Marc M; MacMicking, John D JD

Publication Date: 2009-08

Variant appearance in text: PI3K: R274A

PubMed Link: 19620982

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Disrupted RabGAP function of the p85 subunit of phosphatidylinositol 3-kinase results in cell transformation.

The Journal Of Biological Chemistry

Chamberlain, M Dean MD; Chan, Tim T; Oberg, Jennifer C JC; Hawrysh, Andrea D AD; James, Kristy M KM; Saxena, Anurag A; Xiang, Jim J; Anderson, Deborah H DH

Publication Date: 2008-06-06

Variant appearance in text: PI3K: R274A

PubMed Link: 18387942

Variant Present in the following documents:

• Main text

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