Publications:

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Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method.

Biorxiv : The Preprint Server For Biology

Mikhaylova, Veronika V; Rzepka, Madison M; Kawamura, Tetsuya T; Xia, Yu Y; Chang, Peter L PL; Zhou, Shiguo S; Pham, Long L; Modi, Naisarg N; Yao, Likun L; Perez-Agustin, Adrian A; Pagans, Sara S; Boles, T Christian TC; Lei, Ming M; Wang, Yong Y; Garcia-Bassets, Ivan I; Chen, Zhoutao Z

Publication Date: 2023-03-06

Variant appearance in text: PIK3CA: I391M; rs2230461

PubMed Link: 36945366

Variant Present in the following documents:

• Main text
• nihpp-2023.03.05.531179v1.pdf

View BVdb publication page

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Response and resistance to BRAFV600E inhibition in gliomas: Roadblocks ahead?

Frontiers In Oncology

Capogiri, Monica M; De Micheli, Andrea J AJ; Lassaletta, Alvaro A; Muñoz, Denise P DP; Coppé, Jean-Philippe JP; Mueller, Sabine S; Guerreiro Stucklin, Ana S AS

Publication Date: 2022

Variant appearance in text: PI3K: I391M

PubMed Link: 36698391

Variant Present in the following documents:

• Main text
• fonc-12-1074726.pdf

View BVdb publication page

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Liquid biopsy of cerebrospinal fluid enables selective profiling of glioma molecular subtypes at first clinical presentation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Orzan, Francesca F; De Bacco, Francesca F; Lazzarini, Elisabetta E; Crisafulli, Giovanni G; Gasparini, Alessandra A; Dipasquale, Angelo A; Barault, Ludovic L; Macagno, Marco M; Persico, Pasquale P; Pessina, Federico F; Bono, Beatrice B; Giordano, Laura L; Zeppa, Pietro P; Melcarne, Antonio A; Cassoni, Paola P; Garbossa, Diego D; Santoro, Armando A; Comoglio, Paolo M PM; Indraccolo, Stefano S; Simonelli, Matteo M; Boccaccio, Carla C

Publication Date: 2023-01-17

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 36648487

Variant Present in the following documents:

• ccr-22-2903_supplementary_data_2_suppds2.xlsx, sheet 3

View BVdb publication page

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Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Cancer Research Communications

Valentine, Henkel H; Aiken, William W; Morrison, Belinda B; Zhao, Ziran Z; Fowle, Holly H; Wasserman, Jason S JS; Thompson, Elon E; Chin, Warren W; Young, Mark M; Clarke, Shannique S; Gibbs, Denise D; Harrison, Sharon S; McLaughlin, Wayne W; Kwok, Tim T; Jin, Fang F; Campbell, Kerry S KS; Horvath, Anelia A; Thompson, Rory R; Lee, Norman H NH; Zhou, Yan Y; Graña, Xavier X; Ragin, Camille C; Badal, Simone S

Publication Date: 2022-11

Variant appearance in text: PIK3CA: I391M; rs2230461

PubMed Link: 36643868

Variant Present in the following documents:

• crc-22-0245-s07.xlsx, sheet 1

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs2230461

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 5

View BVdb publication page

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Circulating tumor DNA mutation profile is associated with the prognosis and treatment response of Chinese patients with newly diagnosed diffuse large B-cell lymphoma.

Frontiers In Oncology

Guan, Tao T; Zhang, Min M; Liu, Xiaolan X; Li, Jing J; Xin, Beibei B; Ren, Yanxin Y; Yang, Yuchao Y; Wang, Hui H; Zhao, Mengjing M; Huang, Yunpeng Y; Guo, Xiaojing X; Du, Jun J; Qian, Wenbin W; Su, Liping L

Publication Date: 2022

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36465410

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 4

View BVdb publication page

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Decellularized extracellular matrix as scaffold for cancer organoid cultures of colorectal peritoneal metastases.

Journal Of Molecular Cell Biology

Varinelli, Luca L; Guaglio, Marcello M; Brich, Silvia S; Zanutto, Susanna S; Belfiore, Antonino A; Zanardi, Federica F; Iannelli, Fabio F; Oldani, Amanda A; Costa, Elisa E; Chighizola, Matteo M; Lorenc, Ewelina E; Minardi, Simone P SP; Fortuzzi, Stefano S; Filugelli, Martina M; Garzone, Giovanna G; Pisati, Federica F; Vecchi, Manuela M; Pruneri, Giancarlo G; Kusamura, Shigeki S; Baratti, Dario D; Cattaneo, Laura L; Parazzoli, Dario D; Podestà, Alessandro A; Milione, Massimo M; Deraco, Marcello M; Pierotti, Marco A MA; Gariboldi, Manuela M

Publication Date: 2022-12-02

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36460033

Variant Present in the following documents:

• mjac064_supplemental_file.pdf

View BVdb publication page

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Preliminary Experience of Liquid Biopsy in Lung Cancer Compared to Conventional Assessment: Light and Shadows.

Journal Of Personalized Medicine

Montella, Marco M; Ciani, Giovanni G; Granata, Vincenza V; Fusco, Roberta R; Grassi, Francesca F; Ronchi, Andrea A; Cozzolino, Immacolata I; Franco, Renato R; Zito Marino, Federica F; Urraro, Fabrizio F; Monti, Riccardo R; Sirica, Roberto R; Savarese, Giovanni G; Chianese, Ugo U; Nebbioso, Angela A; Altucci, Lucia L; Vietri, Maria Teresa MT; Nardone, Valerio V; Reginelli, Alfonso A; Grassi, Roberta R

Publication Date: 2022-11-12

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 36422072

Variant Present in the following documents:

• Main text
• jpm-12-01896.pdf

View BVdb publication page

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JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.

Cancer Research

Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K

Publication Date: 2022-11-21

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 36409824

Variant Present in the following documents:

• can-22-0423_supplementary_table_s3_suppst3.xlsx, sheet 1

View BVdb publication page

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Dental DNA as an Indicator of Post-Mortem Interval (PMI): A Pilot Research.

International Journal Of Molecular Sciences

Bianchi, Ilenia I; Grassi, Simone S; Castiglione, Francesca F; Bartoli, Caterina C; De Saint Pierre, Bianca B; Focardi, Martina M; Oliva, Antonio A; Pinchi, Vilma V

Publication Date: 2022-10-25

Variant appearance in text: PIK3CA: 1173A>G

PubMed Link: 36361687

Variant Present in the following documents:

• ijms-23-12896.pdf

View BVdb publication page

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Monitoring of circulating tumor DNA predicts response to treatment and early progression in follicular lymphoma: results of a prospective pilot study.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Fernández-Miranda, Ismael I; Pedrosa, Lucia L; Llanos, Marta M; Franco, Fernando F FF; Gómez, Sagrario S; Martín-Acosta, Paloma P; García-Arroyo, Francisco R FR; Gumà, Josep J; Horcajo, Beatriz B; Ballesteros, Ana K AK; Gálvez, Laura L; Martínez, Natividad N; Marín, Miguel M; Sequero, Silvia S; Navarro, Marta M; Yanguas-Casás, Natalia N; Calvo, Virginia V; Rueda-Domínguez, Antonio A; Provencio, Mariano M; Sánchez-Beato, Margarita M

Publication Date: 2022-10-21

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36269794

Variant Present in the following documents:

• ccr-22-1654_supplementary_data_2_suppds2.xlsx, sheet 6

View BVdb publication page

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ATF4-dependent fructolysis fuels growth of glioblastoma multiforme.

Nature Communications

Chen, Chao C; Zhang, Zhenxing Z; Liu, Caiyun C; Wang, Bin B; Liu, Ping P; Fang, Shu S; Yang, Fan F; You, Yongping Y; Li, Xinjian X

Publication Date: 2022-10-16

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 36245009

Variant Present in the following documents:

• 41467_2022_33859_MOESM1_ESM.pdf

View BVdb publication page

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Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM15_ESM.xlsx, sheet 2

View BVdb publication page

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Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.

Pathobiology : Journal Of Immunopathology, Molecular And Cellular Biology

Haefliger, Simon S; Marston, Katharina K; Alborelli, Ilaria I; Stauffer, Edouard-Jean EJ; Gugger, Mathias M; Jermann, Philip M PM; Hoeller, Sylvia S; Tornillo, Luigi L; Terracciano, Luigi M LM; Bihl, Michel M; Matter, Matthias S MS

Publication Date: 2022-10-06

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36202073

Variant Present in the following documents:

• pat-0090-0166-s01.pdf

View BVdb publication page

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Genomic Landscape Alterations in Primary Tumor and Matched Lymph Node Metastasis in Hormone-Naïve Prostate Cancer Patients.

Cancers

Russo, Giorgio Ivan GI; Bonacci, Paolo P; Bivona, Dalida D; Privitera, Grete Francesca GF; Broggi, Giuseppe G; Caltabiano, Rosario R; Vella, Jessica J; Lo Giudice, Arturo A; Asmundo, Maria Giovanna MG; Cimino, Sebastiano S; Morgia, Giuseppe G; Stefani, Stefania S; Musso, Nicolò N

Publication Date: 2022-08-30

Variant appearance in text: rs2230461

PubMed Link: 36077746

Variant Present in the following documents:

• cancers-14-04212.pdf

View BVdb publication page

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A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non-Small Cell Lung Cancer.

Cancer Research

Woo, Xing Yi XY; Srivastava, Anuj A; Mack, Philip C PC; Graber, Joel H JH; Sanderson, Brian J BJ; Lloyd, Michael W MW; Chen, Mandy M; Domanskyi, Sergii S; Gandour-Edwards, Regina R; Tsai, Rebekah A RA; Keck, James J; Cheng, Mingshan M; Bundy, Margaret M; Jocoy, Emily L EL; Riess, Jonathan W JW; Holland, William W; Grubb, Stephen C SC; Peterson, James G JG; Stafford, Grace A GA; Paisie, Carolyn C; Neuhauser, Steven B SB; Karuturi, R Krishna Murthy RKM; George, Joshy J; Simons, Allen K AK; Chavaree, Margaret M; Tepper, Clifford G CG; Goodwin, Neal N; Airhart, Susan D SD; Lara, Primo N PN; Openshaw, Thomas H TH; Liu, Edison T ET; Gandara, David R DR; Bult, Carol J CJ

Publication Date: 2022-11-15

Variant appearance in text: PIK3CA: I391M

PubMed Link: 36069866

Variant Present in the following documents:

• can-22-0948_table_s1_suppst1.xlsx, sheet 1

View BVdb publication page

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KIT Mutations Correlate with Higher Galectin Levels and Brain Metastasis in Breast and Non-Small Cell Lung Cancer.

Cancers

Funkhouser, Avery T AT; Strigenz, Alexander M AM; Blair, Bailey B BB; Miller, Andrew P AP; Shealy, Jonah C JC; Ewing, Joseph A JA; Martin, Julie C JC; Funk, Christopher R CR; Edenfield, William J WJ; Blenda, Anna V AV

Publication Date: 2022-06-03

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 35681762

Variant Present in the following documents:

• cancers-14-02781.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications.

Frontiers In Oncology

Tirrò, Elena E; Massimino, Michele M; Broggi, Giuseppe G; Romano, Chiara C; Minasi, Simone S; Gianno, Francesca F; Antonelli, Manila M; Motta, Gianmarco G; Certo, Francesco F; Altieri, Roberto R; Manzella, Livia L; Caltabiano, Rosario R; Barbagallo, Giuseppe Maria Vincenzo GMV; Buttarelli, Francesca Romana FR; Magro, Gaetano G; Giangaspero, Felice F; Vigneri, Paolo P

Publication Date: 2022

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 35372034

Variant Present in the following documents:

• Table_4.xlsx, sheet 1

View BVdb publication page

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Detection of genetic mutations in patients with breast cancer from Saudi Arabia using Ion AmpliSeq™ Cancer Hotspot Panel v.2.0.

Biomedical Reports

Messaoudi, Safia A SA; Al Sharhan, Nourah A NA; Alharthi, Bandar B; Babu, Saranya R SR; Alsaleh, Abrar B AB; Alasiri, Alanoud M AM; Assidi, Mourad M; Buhmeida, Abdelbaset A; Almawi, Wassim Y WY

Publication Date: 2022-04

Variant appearance in text: PIK3CA: 1173A>G

PubMed Link: 35251613

Variant Present in the following documents:

• Main text
• br-16-04-01509.pdf

View BVdb publication page

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Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.

Journal Of Cancer Research And Clinical Oncology

Kleo, Karsten K; Jovanovic, Vladimir M VM; Arndold, Alexander A; Lehmann, Annika A; Lammert, Hedwig H; Berg, Erika E; Harloff, Hannah H; Treese, Christoph C; Hummel, Michael M; Daum, Severin S

Publication Date: 2022-03-05

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 35246724

Variant Present in the following documents:

• 432_2022_3944_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology

Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD

Publication Date: 2021-11-18

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 34797250

Variant Present in the following documents:

• ct9-12-e00431-s005.xlsx, sheet 1
• ct9-12-e00431-s006.xlsx, sheet 1

View BVdb publication page

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Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.

Oncogene

Findlay, Izac J IJ; De Iuliis, Geoffry N GN; Duchatel, Ryan J RJ; Jackson, Evangeline R ER; Vitanza, Nicholas A NA; Cain, Jason E JE; Waszak, Sebastian M SM; Dun, Matthew D MD

Publication Date: 2021-11-10

Variant appearance in text: PIK3CA: I391M

PubMed Link: 34759345

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.

Oncogene

Findlay, Izac J IJ; De Iuliis, Geoffry N GN; Duchatel, Ryan J RJ; Jackson, Evangeline R ER; Vitanza, Nicholas A NA; Cain, Jason E JE; Waszak, Sebastian M SM; Dun, Matthew D MD

Publication Date: 2022-01

Variant appearance in text: PIK3CA: I391M

PubMed Link: 34759345

Variant Present in the following documents:

• Main text

View BVdb publication page

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A rare case of omental extra-gastrointestinal stromal tumor showing two coexisting mutations on exon 14 of the PDGFRA gene.

Gastroenterology Report

Caruso, Gianluca G; Pacini, Luca L; Iossa, Angelo A; Di Cristofano, Claudio C; Bastianelli, Daniela D; Silecchia, Gianfranco G; Mele, Maria M; Petrozza, Vincenzo V; Calogero, Antonella A; De Falco, Elena E

Publication Date: 2021-08

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 34567572

Variant Present in the following documents:

• Main text
• goaa086.pdf

View BVdb publication page

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Circulating TP53 mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX.

Therapeutic Advances In Medical Oncology

van der Sijde, Fleur F; Azmani, Zakia Z; Besselink, Marc G MG; Bonsing, Bert A BA; de Groot, Jan Willem B JWB; Groot Koerkamp, Bas B; Haberkorn, Brigitte C M BCM; Homs, Marjolein Y V MYV; van IJcken, Wilfred F J WFJ; Janssen, Quisette P QP; Lolkema, Martijn P MP; Luelmo, Saskia A C SAC; Mekenkamp, Leonie J M LJM; Mustafa, Dana A M DAM; van Schaik, Ron H N RHN; Wilmink, Johanna W JW; Vietsch, Eveline E EE; van Eijck, Casper H J CHJ

Publication Date: 2021

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 34422118

Variant Present in the following documents:

• Main text
• 10.1177_17588359211033704.pdf

View BVdb publication page

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Assessing Genetic Variants in Matched Biocompartments From Patients With Serous Ovarian Cancer.

Technology In Cancer Research & Treatment

Sanders, Brooke E BE; Ku, Lisa L; Walker, Paul P; Bitler, Benjamin G BG

Publication Date: 2021

Variant appearance in text: PIK3CA: I391M

PubMed Link: 34169762

Variant Present in the following documents:

• Main text
• 10.1177_15330338211027917.pdf

View BVdb publication page

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Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors.

International Journal Of Molecular Sciences

Grzywa, Tomasz M TM; Koppolu, Agnieszka A AA; Paskal, Wiktor W; Klicka, Klaudia K; Rydzanicz, Małgorzata M; Wejman, Jarosław J; Płoski, Rafał R; Włodarski, Paweł K PK

Publication Date: 2021-04-09

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met

PubMed Link: 33918692

Variant Present in the following documents:

• Main text

View BVdb publication page

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Concomitant Mutations G12D and G13D on the Exon 2 of the KRAS Gene: Two Cases of Women with Colon Adenocarcinoma.

Diagnostics (Basel, Switzerland)

De Falco, Elena E; Pacini, Luca L; Bastianelli, Daniela D; Spinelli, Gian Paolo GP; Spoto, Chiara C; Veltri, Enzo E; Calogero, Antonella A

Publication Date: 2021-04-06

Variant appearance in text: PIK3CA: 1173A>G; I391M

PubMed Link: 33917572

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Genetic Germline Background of Single and Multiple Primary Melanomas.

Frontiers In Molecular Biosciences

De Summa, Simona S; Lasorella, Antonia A; Strippoli, Sabino S; Giudice, Giuseppe G; Guida, Gabriella G; Elia, Rossella R; Nacchiero, Eleonora E; Azzariti, Amalia A; Silvestris, Nicola N; Guida, Michele M; Guida, Stefania S; Tommasi, Stefania S; Pinto, Rosamaria R

Publication Date: 2020

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33748184

Variant Present in the following documents:

• Main text
• fmolb-07-555630.pdf

View BVdb publication page

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Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome.

Translational Lung Cancer Research

Pavan, Alberto A; Bragadin, Andrea Boscolo AB; Calvetti, Lorenzo L; Ferro, Alessandra A; Zulato, Elisabetta E; Attili, Ilaria I; Nardo, Giorgia G; Dal Maso, Alessandro A; Frega, Stefano S; Menin, Andrea Giovanni AG; Fassan, Matteo M; Calabrese, Fiorella F; Pasello, Giulia G; Guarneri, Valentina V; Aprile, Giuseppe G; Conte, PierFranco P; Rosell, Rafael R; Indraccolo, Stefano S; Bonanno, Laura L

Publication Date: 2021-01

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33569305

Variant Present in the following documents:

• tlcr-10-01-202-supplementary.pdf

View BVdb publication page

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Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One

Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R

Publication Date: 2021

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33556149

Variant Present in the following documents:

• pone.0246048.s008.xlsx, sheet 1

View BVdb publication page

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Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK.

Bmc Cancer

Tran, Khanh B KB; Kolekar, Sharada S; Jabed, Anower A; Jaynes, Patrick P; Shih, Jen-Hsing JH; Wang, Qian Q; Flanagan, Jack U JU; Rewcastle, Gordon W GW; Baguley, Bruce C BC; Shepherd, Peter R PR

Publication Date: 2021-02-06

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33549048

Variant Present in the following documents:

• Main text
• 12885_2021_Article_7826.pdf

View BVdb publication page

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Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.

Npj Systems Biology And Applications

Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A

Publication Date: 2021-01-08

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33420045

Variant Present in the following documents:

• 41540_2020_161_MOESM3_ESM.xlsx, sheet 4
• 41540_2020_161_MOESM3_ESM.xlsx, sheet 3
• 41540_2020_161_MOESM3_ESM.xlsx, sheet 2

View BVdb publication page

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The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.

British Journal Of Cancer

Salas-Benito, Diego D; Conde, Enrique E; Tamayo-Uria, Ibon I; Mancheño, Uxua U; Elizalde, Edurne E; Garcia-Ros, David D; Aramendia, Jose M JM; Muruzabal, Juan C JC; Alcaide, Julia J; Guillen-Grima, Francisco F; Minguez, Jose A JA; Amores-Tirado, Jose J; Gonzalez-Martin, Antonio A; Sarobe, Pablo P; Lasarte, Juan J JJ; Ponz-Sarvise, Mariano M; De Andrea, Carlos E CE; Hervas-Stubbs, Sandra S

Publication Date: 2021-03

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met; rs2230461

PubMed Link: 33402737

Variant Present in the following documents:

• 41416_2020_1218_MOESM2_ESM.xlsx, sheet 1
• 41416_2020_1218_MOESM2_ESM.xlsx, sheet 2

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Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI).

Diagnostic Pathology

Vanni, Irene I; Casula, Milena M; Pastorino, Lorenza L; Manca, Antonella A; Dalmasso, Bruna B; Andreotti, Virginia V; Pisano, Marina M; Colombino, Maria M; , ; Pfeffer, Ulrich U; Tanda, Enrica Teresa ET; Rozzo, Carla C; Paliogiannis, Panagiotis P; Cossu, Antonio A; Ghiorzo, Paola P; Palmieri, Giuseppe G; ,

Publication Date: 2020-12-14

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 33317587

Variant Present in the following documents:

• 13000_2020_1052_MOESM4_ESM.xlsx, sheet 1
• 13000_2020_1052_MOESM2_ESM.xlsx, sheet 1
• 13000_2020_1052_MOESM5_ESM.xlsx, sheet 1
• 13000_2020_1052_MOESM3_ESM.xlsx, sheet 1

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Whole-exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma.

The Journal Of Pathology. Clinical Research

D'Alfonso, Timothy M TM; Pareja, Fresia F; Da Cruz Paula, Arnaud A; Vahdatinia, Mahsa M; Gazzo, Andrea A; Ferrando, Lorenzo L; da Silva, Edaise M EM; Cheng, Esther E; Sclafani, Lisa L; Chandarlapaty, Sarat S; Zhang, Hong H; Hoda, Syed A SA; Wen, Hannah Y HY; Brogi, Edi E; Weigelt, Britta B; Reis-Filho, Jorge S JS

Publication Date: 2021-03

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33263939

Variant Present in the following documents:

• Main text
• CJP2-7-113.pdf

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Mixed large cell neuroendocrine carcinoma and squamous cell carcinoma of the colon: detailed molecular characterisation of two cases indicates a distinct colorectal cancer entity.

The Journal Of Pathology. Clinical Research

Woischke, Christine C; Jung, Peter P; Jung, Andreas A; Kumbrink, Jörg J; Eisenlohr, Sibylle S; Auernhammer, Christoph Josef CJ; Vieth, Michael M; Kirchner, Thomas T; Neumann, Jens J

Publication Date: 2021-01

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met

PubMed Link: 33197299

Variant Present in the following documents:

• Main text

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Molecular genomic features associated with in vitro response of the NCI-60 cancer cell line panel to natural products.

Molecular Oncology

Krushkal, Julia J; Negi, Simarjeet S; Yee, Laura M LM; Evans, Jason R JR; Grkovic, Tanja T; Palmisano, Alida A; Fang, Jianwen J; Sankaran, Hari H; McShane, Lisa M LM; Zhao, Yingdong Y; O'Keefe, Barry R BR

Publication Date: 2021-02

Variant appearance in text: PIK3CA: I391M

PubMed Link: 33169510

Variant Present in the following documents:

• MOL2-15-381-s009.xlsx, sheet 1

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Comparing cell-free circulating tumor DNA mutational profiles of disease-free and nonresponders patients with oropharyngeal squamous cell carcinoma.

Laryngoscope Investigative Otolaryngology

Khandelwal, Alok R AR; Greer, Adam H AH; Hamiter, Mickie M; Fermin, Janmaris Marin JM; McMullen, Thomas T; Moore-Medlin, Tara T; Mills, Glenn G; Flores, Jose M JM; Yin, Hong H; Nathan, Cherie-Ann O CO

Publication Date: 2020-10

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 33134534

Variant Present in the following documents:

• Main text
• LIO2-5-868.pdf

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BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer.

Communications Biology

Conciatori, Fabiana F; Bazzichetto, Chiara C; Amoreo, Carla Azzurra CA; Sperduti, Isabella I; Donzelli, Sara S; Diodoro, Maria Grazia MG; Buglioni, Simonetta S; Falcone, Italia I; Shirasawa, Senji S; Blandino, Giovanni G; Ferretti, Gianluigi G; Cognetti, Francesco F; Milella, Michele M; Ciuffreda, Ludovica L

Publication Date: 2020-10-01

Variant appearance in text: PI3K: I391M

PubMed Link: 33004975

Variant Present in the following documents:

• Main text

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Acute Radiation Colitis after Preoperative Short-Course Radiotherapy for Rectal Cancer: A Morphological, Immunohistochemical and Genetic Study.

Cancers

Zanelli, Magda M; Ciarrocchi, Alessia A; De Petris, Giovanni G; Zizzo, Maurizio M; Costantini, Massimo M; Bisagni, Alessandra A; Torricelli, Federica F; Nicoli, Davide D; Ramundo, Dafne D; Ricci, Stefano S; Palicelli, Andrea A; Sanguedolce, Francesca F; Ascani, Stefano S; Castro Ruiz, Carolina C; Annessi, Valerio V; Zamponi, Raffaella R; Bortesi, Mara M; Martino, Veronica V; Marchetti, Marialisa M; De Marco, Loredana L

Publication Date: 2020-09-09

Variant appearance in text: PIK3CA: Ile391Met

PubMed Link: 32917028

Variant Present in the following documents:

• cancers-12-02571-s001.pdf

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Somatic Mutation Profiling in Premalignant Lesions of Vulvar Squamous Cell Carcinoma.

International Journal Of Molecular Sciences

Zięba, Sebastian S; Pouwer, Anne-Floor W AW; Kowalik, Artur A; Zalewski, Kamil K; Rusetska, Natalia N; Bakuła-Zalewska, Elwira E; Kopczyński, Janusz J; Pijnenborg, Johanna M A JMA; de Hullu, Joanne A JA; Kowalewska, Magdalena M

Publication Date: 2020-07-10

Variant appearance in text: PIK3CA: I391M

PubMed Link: 32664330

Variant Present in the following documents:

• Main text

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TP53, ATRX alterations, and low tumor mutation load feature IDH-wildtype giant cell glioblastoma despite exceptional ultra-mutated tumors.

Neuro-Oncology Advances

Cantero, Diana D; Mollejo, Manuela M; Sepúlveda, Juan M JM; D'Haene, Nicky N; Gutiérrez-Guamán, Myriam J MJ; Rodríguez de Lope, Ángel Á; Fiaño, Concepción C; Castresana, Javier S JS; Lebrun, Laetitia L; Rey, Juan A JA; Salmon, Isabelle I; Meléndez, Bárbara B; Hernández-Laín, Aurelio A

Publication Date: 2020

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met

PubMed Link: 32642724

Variant Present in the following documents:

• vdz059_suppl_suplementary_table_2.xlsx, sheet 1

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Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing.

F1000Research

Butt, Ejaz E; Alyami, Sabra S; Nageeti, Tahani T; Saeed, Muhammad M; AlQuthami, Khalid K; Bouazzaoui, Abdellatif A; Athar, Mohammad M; Abduljaleel, Zainularifeen Z; Al-Allaf, Faisal F; Taher, Mohiuddin M

Publication Date: 2019

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met

PubMed Link: 32612806

Variant Present in the following documents:

• Main text

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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids.

Cell

Koundouros, Nikos N; Karali, Evdoxia E; Tripp, Aurelien A; Valle, Adamo A; Inglese, Paolo P; Perry, Nicholas J S NJS; Magee, David J DJ; Anjomani Virmouni, Sara S; Elder, George A GA; Tyson, Adam L AL; Dória, Maria Luisa ML; van Weverwijk, Antoinette A; Soares, Renata F RF; Isacke, Clare M CM; Nicholson, Jeremy K JK; Glen, Robert C RC; Takats, Zoltan Z; Poulogiannis, George G

Publication Date: 2020-06-25

Variant appearance in text: PIK3CA: I391M

PubMed Link: 32559461

Variant Present in the following documents:

• Main text
• mmc5.xlsx, sheet 1

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TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients.

Journal Of Experimental & Clinical Cancer Research : Cr

Dinami, Roberto R; Porru, Manuela M; Amoreo, Carla Azzurra CA; Sperduti, Isabella I; Mottolese, Marcella M; Buglioni, Simonetta S; Marinelli, Daniele D; Maugeri-Saccà, Marcello M; Sacconi, Andrea A; Blandino, Giovanni G; Leonetti, Carlo C; Di Rocco, Giuliana G; Verdina, Alessandra A; Spinella, Francesca F; Fiorentino, Francesco F; Ciliberto, Gennaro G; Biroccio, Annamaria A; Zizza, Pasquale P

Publication Date: 2020-06-15

Variant appearance in text: PIK3CA: I391M

PubMed Link: 32539869

Variant Present in the following documents:

• 13046_2020_1612_MOESM2_ESM.xlsx, sheet 1

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Cas9 activates the p53 pathway and selects for p53-inactivating mutations.

Nature Genetics

Enache, Oana M OM; Rendo, Veronica V; Abdusamad, Mai M; Lam, Daniel D; Davison, Desiree D; Pal, Sangita S; Currimjee, Naomi N; Hess, Julian J; Pantel, Sasha S; Nag, Anwesha A; Thorner, Aaron R AR; Doench, John G JG; Vazquez, Francisca F; Beroukhim, Rameen R; Golub, Todd R TR; Ben-David, Uri U

Publication Date: 2020-07

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 32424350

Variant Present in the following documents:

• NIHMS1581982-supplement-1581982_Supp_Dataset1-7.xlsx, sheet 7

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Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis.

International Medical Case Reports Journal

Jastania, Raid A RA; Saeed, Muhammad M; Al-Khalidi, Hisham H; AlQuthami, Khalid K; Nageeti, Tahani H TH; Al-Allaf, Faisal A FA; Valerie, Kristoffer K; Taher, Mohiuddin M MM

Publication Date: 2020

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met; rs2230461

PubMed Link: 32368160

Variant Present in the following documents:

• Main text

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Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients.

Journal Of Advanced Research

Nassar, Auhood A; Abouelhoda, Mohamed M; Mansour, Osman O; Loutfy, Samah A SA; Hafez, Mohamed M MM; Gomaa, M M; Bahnassy, Abeer A; El-Din Youssef, Amira Salah AS; Lotfy, Mai M MM; Ismail, Hoda H; Ahmed, Ola S OS; Abou-Bakr, Amany Abd-Elhameed AA; Zekri, Abdel-Rahman N AN

Publication Date: 2020-07

Variant appearance in text: PIK3CA: 1173A>G

PubMed Link: 32322420

Variant Present in the following documents:

• Main text

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Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor.

Biological Research

García, Patricia P; Bizama, Carolina C; Rosa, Lorena L; Espinoza, Jaime A JA; Weber, Helga H; Cerda-Infante, Javier J; Sánchez, Marianela M; Montecinos, Viviana P VP; Lorenzo-Bermejo, Justo J; Boekstegers, Felix F; Dávila-López, Marcela M; Alfaro, Francisca F; Leiva-Acevedo, Claudia C; Parra, Zasha Z; Romero, Diego D; Kato, Sumie S; Leal, Pamela P; Lagos, Marcela M; Roa, Juan Carlos JC

Publication Date: 2020-04-15

Variant appearance in text: rs2230461

PubMed Link: 32293552

Variant Present in the following documents:

• Main text

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A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 (capivasertib) in patients with metastatic castration-resistant prostate cancer.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Kolinsky, M P MP; Rescigno, P P; Bianchini, D D; Zafeiriou, Z Z; Mehra, N N; Mateo, J J; Michalarea, V V; Riisnaes, R R; Crespo, M M; Figueiredo, I I; Miranda, S S; Nava Rodrigues, D D; Flohr, P P; Tunariu, N N; Banerji, U U; Ruddle, R R; Sharp, A A; Welti, J J; Lambros, M M; Carreira, S S; Raynaud, F I FI; Swales, K E KE; Plymate, S S; Luo, J J; Tovey, H H; Porta, N N; Slade, R R; Leonard, L L; Hall, E E; de Bono, J S JS

Publication Date: 2020-05

Variant appearance in text: PIK3CA: I391M

PubMed Link: 32205016

Variant Present in the following documents:

• Main text
• mmc9.xlsx, sheet 1
• main.pdf

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Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study.

Current Oncology (Toronto, Ont.)

Spence, T T; Stickle, N N; Yu, C C; Chow, H H; Feilotter, H H; Lo, B B; McCready, E E; Sadikovic, B B; Siu, L L LL; Bedard, P L PL; Stockley, T L TL

Publication Date: 2019-12

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met

PubMed Link: 31896942

Variant Present in the following documents:

• Main text

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Genomics of lethal prostate cancer at diagnosis and castration resistance.

The Journal Of Clinical Investigation

Mateo, Joaquin J; Seed, George G; Bertan, Claudia C; Rescigno, Pasquale P; Dolling, David D; Figueiredo, Ines I; Miranda, Susana S; Nava Rodrigues, Daniel D; Gurel, Bora B; Clarke, Matthew M; Atkin, Mark M; Chandler, Rob R; Messina, Carlo C; Sumanasuriya, Semini S; Bianchini, Diletta D; Barrero, Maialen M; Petermolo, Antonella A; Zafeiriou, Zafeiris Z; Fontes, Mariane M; Perez-Lopez, Raquel R; Tunariu, Nina N; Fulton, Ben B; Jones, Robert R; McGovern, Ursula U; Ralph, Christy C; Varughese, Mohini M; Parikh, Omi O; Jain, Suneil S; Elliott, Tony T; Sandhu, Shahneen S; Porta, Nuria N; Hall, Emma E; Yuan, Wei W; Carreira, Suzanne S; de Bono, Johann S JS

Publication Date: 2020-04-01

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 31874108

Variant Present in the following documents:

• jci-130-132031-s100.xlsx, sheet 1

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Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer.

Scientific Reports

D'Oronzo, Stella S; Lovero, Domenica D; Palmirotta, Raffaele R; Stucci, Luigia Stefania LS; Tucci, Marco M; Felici, Claudia C; Cascardi, Eliano E; Giardina, Carmela C; Cafforio, Paola P; Silvestris, Franco F

Publication Date: 2019-11-21

Variant appearance in text: PIK3CA: 1173A>G; I391M; rs2230461

PubMed Link: 31754145

Variant Present in the following documents:

• 41598_2019_53660_MOESM1_ESM.pdf

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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.

Science (New York, N.Y.)

Vasan, Neil N; Razavi, Pedram P; Johnson, Jared L JL; Shao, Hong H; Shah, Hardik H; Antoine, Alesia A; Ladewig, Erik E; Gorelick, Alexander A; Lin, Ting-Yu TY; Toska, Eneda E; Xu, Guotai G; Kazmi, Abiha A; Chang, Matthew T MT; Taylor, Barry S BS; Dickler, Maura N MN; Jhaveri, Komal K; Chandarlapaty, Sarat S; Rabadan, Raul R; Reznik, Ed E; Smith, Melissa L ML; Sebra, Robert R; Schimmoller, Frauke F; Wilson, Timothy R TR; Friedman, Lori S LS; Cantley, Lewis C LC; Scaltriti, Maurizio M; Baselga, José J

Publication Date: 2019-11-08

Variant appearance in text: PIK3CA: I391M

PubMed Link: 31699932

Variant Present in the following documents:

• Main text

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Connecting the dots between different networks: miRNAs associated with bladder cancer risk and progression.

Journal Of Experimental & Clinical Cancer Research : Cr

Braicu, Cornelia C; Buiga, Rares R; Cojocneanu, Roxana R; Buse, Mihail M; Raduly, Lajos L; Pop, Laura Ancuta LA; Chira, Sergiu S; Budisan, Liviuta L; Jurj, Ancuta A; Ciocan, Cristina C; Magdo, Lorand L; Irimie, Alexandru A; Dobrota, Florentin F; Petrut, Bogdan B; Berindan-Neagoe, Ioana I

Publication Date: 2019-10-29

Variant appearance in text: PIK3CA: 1173A>G; Ile391Met; rs2230461

PubMed Link: 31665050

Variant Present in the following documents:

• 13046_2019_1406_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

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