Publications:

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Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.

The Journal Of Experimental Medicine

Saei, Azad A; Palafox, Marta M; Benoukraf, Touati T; Kumari, Nishi N; Jaynes, Patrick William PW; Iyengar, Prasanna Vasudevan PV; Muñoz-Couselo, Eva E; Nuciforo, Paolo P; Cortés, Javier J; Nötzel, Christopher C; Kumarakulasinghe, Nesaretnam Barr NB; Richard, John Lalith Charles JLC; Bin Adam Isa, Zul Fazreen ZF; Pang, Brendan B; Guzman, Marta M; Siqin, Zhou Z; Yang, Henry H; Tam, Wai Leong WL; Serra, Violeta V; Eichhorn, Pieter Johan Adam PJA

Publication Date: 2018-07-02

Variant appearance in text: PI3K: S408A

PubMed Link: 29880484

Variant Present in the following documents:

• JEM_20171960.pdf

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Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function.

Plos One

Lahey, Kelcie A KA; Ronaghan, Natalie J NJ; Shang, Judie J; Dion, Sébastien P SP; Désilets, Antoine A; Leduc, Richard R; MacNaughton, Wallace K WK

Publication Date: 2017

Variant appearance in text: PI3K: S408A

PubMed Link: 28671992

Variant Present in the following documents:

• Main text
• pone.0180259.pdf

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Regulation of GABAARs by phosphorylation.

Advances In Pharmacology (San Diego, Calif.)

Nakamura, Yasuko Y; Darnieder, Laura M LM; Deeb, Tarek Z TZ; Moss, Stephen J SJ

Publication Date: 2015

Variant appearance in text: PI3K: S408A

PubMed Link: 25600368

Variant Present in the following documents:

• Main text

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CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity.

Cell Communication And Signaling : Ccs

Dörfel, Max J MJ; Westphal, Julie K JK; Bellmann, Christian C; Krug, Susanne M SM; Cording, Jimmi J; Mittag, Sonnhild S; Tauber, Rudolf R; Fromm, Michael M; Blasig, Ingolf E IE; Huber, Otmar O

Publication Date: 2013-06-10

Variant appearance in text: PI3K: S408A

PubMed Link: 23758859

Variant Present in the following documents:

• 1478-811X-11-40.pdf

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Modulation of tight junction structure and function by kinases and phosphatases targeting occludin.

Journal Of Biomedicine & Biotechnology

Dörfel, Max Johannes MJ; Huber, Otmar O

Publication Date: 2012

Variant appearance in text: PI3K: S408A

PubMed Link: 22315516

Variant Present in the following documents:

• Main text
• JBB2012-807356.pdf

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A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1).

Molecular Endocrinology (Baltimore, Md.)

Boura-Halfon, Sigalit S; Shuster-Meiseles, Timor T; Beck, Avital A; Petrovich, Katia K; Gurevitch, Diana D; Ronen, Denise D; Zick, Yehiel Y

Publication Date: 2010-11

Variant appearance in text: PI3K: S408A

PubMed Link: 20843941

Variant Present in the following documents:

• Main text

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Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.

Molecular And Cellular Biology

Liu, Yan-Fang YF; Herschkovitz, Avia A; Boura-Halfon, Sigalit S; Ronen, Denise D; Paz, Keren K; Leroith, Derek D; Zick, Yehiel Y

Publication Date: 2004-11

Variant appearance in text: PI3K: S408A

PubMed Link: 15485932

Variant Present in the following documents:

• Main text

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