PIK3CA c.1253A>G ;(p.E418G)

Variant ID: 3-178927975-A-G

NM_006218.2(PIK3CA):c.1253A>G;(p.E418G)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Publication Date: 2020-07-30

Variant appearance in text: PIK3CA: E418G
PubMed Link: 32732999
Variant Present in the following documents:
  • 41467_2020_17659_MOESM3_ESM.xls, sheet 1
View BVdb publication page



A Phase II Trial of Neoadjuvant MK-2206, an AKT Inhibitor, with Anastrozole in Clinical Stage II or III PIK3CA-Mutant ER-Positive and HER2-Negative Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Ma, Cynthia X CX; Suman, Vera V; Goetz, Matthew P MP; Northfelt, Donald D; Burkard, Mark E ME; Ademuyiwa, Foluso F; Naughton, Michael M; Margenthaler, Julie J; Aft, Rebecca R; Gray, Richard R; Tevaarwerk, Amye A; Wilke, Lee L; Haddad, Tufia T; Moynihan, Timothy T; Loprinzi, Charles C; Hieken, Tina T; Barnell, Erica K EK; Skidmore, Zachary L ZL; Feng, Yan-Yang YY; Krysiak, Kilannin K; Hoog, Jeremy J; Guo, Zhanfang Z; Nehring, Leslie L; Wisinski, Kari B KB; Mardis, Elaine E; Hagemann, Ian S IS; Vij, Kiran K; Sanati, Souzan S; Al-Kateb, Hussam H; Griffith, Obi L OL; Griffith, Malachi M; Doyle, Laurence L; Erlichman, Charles C; Ellis, Matthew J MJ
Publication Date: 2017-11-15

Variant appearance in text: PIK3CA: E418G
PubMed Link: 28874413
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: PIK3CA: 1253A>G; E418G
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page