Publications:

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Circulating Cell-Free DNA-Based Comprehensive Molecular Analysis of Biliary Tract Cancers Using Next-Generation Sequencing.

Cancers

Csoma, Szilvia Lilla SL; Bedekovics, Judit J; Veres, Gergő G; Árokszállási, Anita A; András, Csilla C; Méhes, Gábor G; Mokánszki, Attila A

Publication Date: 2022-01-04

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 35008396

Variant Present in the following documents:

• Main text
• cancers-14-00233.pdf

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Circulating Cell-Free DNA-Based Comprehensive Molecular Analysis of Biliary Tract Cancers Using Next-Generation Sequencing.

Cancers

Csoma, Szilvia Lilla SL; Bedekovics, Judit J; Veres, Gergő G; Árokszállási, Anita A; András, Csilla C; Méhes, Gábor G; Mokánszki, Attila A

Publication Date: 2022-01-04

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 35008396

Variant Present in the following documents:

• Main text
• cancers-14-00233.pdf

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Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors.

The Journal Of Pathology. Clinical Research

Tsybrovskyy, Oleksiy O; De Luise, Monica M; de Biase, Dario D; Caporali, Leonardo L; Fiorini, Claudio C; Gasparre, Giuseppe G; Carelli, Valerio V; Hackl, Dominik D; Imamovic, Larisa L; Haim, Silke S; Sobrinho-Simões, Manuel M; Tallini, Giovanni G

Publication Date: 2022-03

Variant appearance in text: PIK3CA: 1571G>A; R524K

PubMed Link: 34792302

Variant Present in the following documents:

• CJP2-8-155-s001.xlsx, sheet 1

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Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors.

The Journal Of Pathology. Clinical Research

Tsybrovskyy, Oleksiy O; De Luise, Monica M; de Biase, Dario D; Caporali, Leonardo L; Fiorini, Claudio C; Gasparre, Giuseppe G; Carelli, Valerio V; Hackl, Dominik D; Imamovic, Larisa L; Haim, Silke S; Sobrinho-Simões, Manuel M; Tallini, Giovanni G

Publication Date: 2021-11-17

Variant appearance in text: PIK3CA: 1571G>A; R524K

PubMed Link: 34792302

Variant Present in the following documents:

• CJP2-8-155-s001.xlsx, sheet 1

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: PIK3CA: R524K

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

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Short tandem repeat profiling for the authentication of cancer stem-like cells.

International Journal Of Cancer

Visconti, Paola P; Parodi, Federica F; Parodi, Barbara B; Casarino, Lucia L; Romano, Paolo P; Buccarelli, Mariachiara M; Pallini, Roberto R; D'Alessandris, Quintino Giorgio QG; Montori, Andrea A; Pilozzi, Emanuela E; Ricci-Vitiani, Lucia L

Publication Date: 2021-03-15

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 33128777

Variant Present in the following documents:

• IJC-148-1489-s001.pdf

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Deep Sequencing Analysis Identified a Specific Subset of Mutations Distinctive of Biphasic Malignant Pleural Mesothelioma.

Cancers

Torricelli, Federica F; Lococo, Filippo F; Di Stefano, Teresa Severina TS; Lorenzini, Eugenia E; Piana, Simonetta S; Valli, Riccardo R; Rena, Ottavio O; Veronesi, Giulia G; Billè, Andrea A; Ciarrocchi, Alessia A

Publication Date: 2020-08-29

Variant appearance in text: PIK3CA: Arg524Lys

PubMed Link: 32872534

Variant Present in the following documents:

• Main text
• cancers-12-02454.pdf

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Segmental Ipsilateral Odontognathic Dysplasia (Mandibular Involvement in Segmental Odontomaxillary Dysplasia?) and Identification of PIK3CA Somatic Variant in Lesional Mandibular Gingival Tissue.

Head And Neck Pathology

Gibson, Tanya M TM; Rafferty, Keith K; Ryan, Elyse E; Ganguly, Arupa A; Koutlas, Ioannis G IG

Publication Date: 2021-03

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 32500425

Variant Present in the following documents:

• Main text

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Pure high-grade papillary urothelial bladder cancer: a luminal-like subgroup with potential for targeted therapy.

Cellular Oncology (Dordrecht)

Schnitzler, Tician T; Ortiz-Brüchle, Nadina N; Schneider, Ursula U; Lurje, Isabella I; Guricova, Karolina K; Buchner, Alexander A; Schulz, Gerald Bastian GB; Heidenreich, Axel A; Gaisa, Nadine Therese NT; Knüchel, Ruth R; Garczyk, Stefan S

Publication Date: 2020-10

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys; rs104885999

PubMed Link: 32445084

Variant Present in the following documents:

• 13402_2020_524_MOESM7_ESM.xlsx, sheet 1

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Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel.

Diagnostics (Basel, Switzerland)

de Biase, Dario D; Acquaviva, Giorgia G; Visani, Michela M; Sanza, Viviana V; Argento, Chiara M CM; De Leo, Antonio A; Maloberti, Thais T; Pession, Annalisa A; Tallini, Giovanni G

Publication Date: 2020-04-23

Variant appearance in text: PIK3CA: 1571G>A; R524K

PubMed Link: 32340363

Variant Present in the following documents:

• diagnostics-10-00250-s001.pdf

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Clinicopathologic features and molecular spectrum of spindle cell and sclerosing rhabdomyosarcomas in the head and neck region.

International Journal Of Clinical And Experimental Pathology

Wang, Yang Y; Li, Jiang J; Tian, Zhen Z; Zhu, Yanbo Y

Publication Date: 2018

Variant appearance in text: PIK3CA: R524K

PubMed Link: 31949721

Variant Present in the following documents:

• Main text

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: PIK3CA: 1571G>A; R524H

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

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Synchronous endometrioid endometrial and ovarian carcinomas are biologically related: A clinico-pathological and molecular (next generation sequencing) study of 22 cases.

Oncology Letters

Hájková, Nikola N; Tichá, Ivana I; Hojný, Jan J; Němejcová, Kristýna K; Bártů, Michaela M; Michálková, Romana R; Zikán, Michal M; Cibula, David D; Laco, Jan J; Geryk, Tomáš T; Méhes, Gábor G; Dundr, Pavel P

Publication Date: 2019-02

Variant appearance in text: PIK3CA: R524K

PubMed Link: 30675285

Variant Present in the following documents:

• Main text
• ol-17-02-2207.pdf

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PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated with chagasic megaesophagus and are associated with a worse patient outcome.

Infectious Agents And Cancer

Munari, Fernanda Franco FF; Cruvinel-Carloni, Adriana A; Lacerda, Croider Franco CF; de Oliveira, Antônio Talvane Torres ATT; Scapulatempo-Neto, Cristovam C; da Silva, Sandra Regina Morini SRM; Crema, Eduardo E; Adad, Sheila Jorge SJ; Rodrigues, Maria Aparecida Marchesan MAM; Henry, Maria Aparecida Coelho Arruda MACA; Guimarães, Denise Peixoto DP; Longatto-Filho, Adhemar A; Reis, Rui Manuel RM

Publication Date: 2018

Variant appearance in text: PIK3CA: R524K

PubMed Link: 30619505

Variant Present in the following documents:

• Main text
• 13027_2018_Article_216.pdf

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Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma.

Molecular Oncology

Calapre, Leslie L; Giardina, Tindaro T; Robinson, Cleo C; Reid, Anna L AL; Al-Ogaili, Zeyad Z; Pereira, Michelle R MR; McEvoy, Ashleigh C AC; Warburton, Lydia L; Hayward, Nicholas K NK; Khattak, Muhammad A MA; Meniawy, Tarek M TM; Millward, Michael M; Amanuel, Benhur B; Ziman, Melanie M; Gray, Elin S ES

Publication Date: 2019-02

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 30312528

Variant Present in the following documents:

• MOL2-13-171-s003.xlsx, sheet 1

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Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine.

Virchows Archiv : An International Journal Of Pathology

Simbolo, Michele M; Vicentini, Caterina C; Mafficini, Andrea A; Fassan, Matteo M; Pedron, Serena S; Corbo, Vincenzo V; Mastracci, Luca L; Rusev, Borislav B; Pedrazzani, Corrado C; Landoni, Luca L; Grillo, Federica F; Cingarlini, Sara S; Rindi, Guido G; Luchini, Claudio C; Scarpa, Aldo A; Lawlor, Rita T RT

Publication Date: 2018-12

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 30219970

Variant Present in the following documents:

• 428_2018_2450_MOESM4_ESM.xlsx, sheet 5

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Prognostic significance of PIK3CA mutation in stage IIB to IVA cervical cancers treated by concurrent chemoradiotherapy with weekly cisplatin.

Medicine

Lachkar, Bouchra B; Minaguchi, Takeo T; Akiyama, Azusa A; Liu, Shuling S; Zhang, Shuang S; Xu, Chenyang C; Shikama, Ayumi A; Tasaka, Nobutaka N; Sakurai, Manabu M; Nakao, Sari S; Ochi, Hiroyuki H; Yoshikawa, Hiroyuki H; Satoh, Toyomi T

Publication Date: 2018-08

Variant appearance in text: PIK3CA: R524K

PubMed Link: 30075505

Variant Present in the following documents:

• medi-97-e11392.pdf

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Mucinous cystadenocarcinoma arising from mucinous cystadenoma of the lung: case report and review of the literature.

Journal Of Thoracic Disease

Moneke, Isabelle I; Zeisel, Christoph C; Elze, Mirjam M; Haager, Benedikt B; Passlick, Bernward B; Kayser, Gian G

Publication Date: 2018-04

Variant appearance in text: PIK3CA: R524K

PubMed Link: 29850162

Variant Present in the following documents:

• Main text

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Germline mutation in the TP53 gene in uveal melanoma.

Scientific Reports

Hajkova, Nikola N; Hojny, Jan J; Nemejcova, Kristyna K; Dundr, Pavel P; Ulrych, Jan J; Jirsova, Katerina K; Glezgova, Johana J; Ticha, Ivana I

Publication Date: 2018-05-16

Variant appearance in text: PIK3CA: 1571G>A; R524K; rs104885999

PubMed Link: 29769598

Variant Present in the following documents:

• 41598_2018_26040_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.

Ebiomedicine

Viel, Alessandra A; Bruselles, Alessandro A; Meccia, Ettore E; Fornasarig, Mara M; Quaia, Michele M; Canzonieri, Vincenzo V; Policicchio, Eleonora E; Urso, Emanuele Damiano ED; Agostini, Marco M; Genuardi, Maurizio M; Lucci-Cordisco, Emanuela E; Venesio, Tiziana T; Martayan, Aline A; Diodoro, Maria Grazia MG; Sanchez-Mete, Lupe L; Stigliano, Vittoria V; Mazzei, Filomena F; Grasso, Francesca F; Giuliani, Alessandro A; Baiocchi, Marta M; Maestro, Roberta R; Giannini, Giuseppe G; Tartaglia, Marco M; Alexandrov, Ludmil B LB; Bignami, Margherita M

Publication Date: 2017-06

Variant appearance in text: PIK3CA: 1571G>A; Arg524Lys

PubMed Link: 28551381

Variant Present in the following documents:

• mmc7.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: PIK3CA: R524K; rs104885999

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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PIK3CA mutations in HER2-positive Breast Cancer Patients; Frequency and Clinicopathological Perspective in Egyptian Patients

Asian Pacific Journal Of Cancer Prevention : Apjcp

Elwy, Fatma F; Helwa, Reham R; El Leithy, Asmaa A AA; Shehab El din, Zeinab Z; Assem, Magda M MM; Hassan, Nagwa H A NH

Publication Date: 2017-01-01

Variant appearance in text: PIK3CA: 1571G>A

PubMed Link: 28240010

Variant Present in the following documents:

• Main text

View BVdb publication page

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Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential novel therapeutic targets.

Oncology Letters

Chen, Shuhui S; Cavazza, Elisa E; Barlier, Catherine C; Salleron, Julia J; Filhine-Tresarrieu, Pierre P; Gavoilles, Céline C; Merlin, Jean-Louis JL; Harlé, Alexandre A

Publication Date: 2016-11

Variant appearance in text: PIK3CA: Arg524Lys

PubMed Link: 27899992

Variant Present in the following documents:

• Main text
• ol-12-05-3264.pdf

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Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Pratz, Keith W KW; Koh, Brian D BD; Patel, Anand G AG; Flatten, Karen S KS; Poh, Weijie W; Herman, James G JG; Dilley, Robert R; Harrell, Maria I MI; Smith, B Douglas BD; Karp, Judith E JE; Swisher, Elizabeth M EM; McDevitt, Michael A MA; Kaufmann, Scott H SH

Publication Date: 2016-08-01

Variant appearance in text: PIK3CA: R524K

PubMed Link: 26979391

Variant Present in the following documents:

• Main text

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PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma.

Bmc Cancer

Chiosea, Simion I SI; Grandis, Jennifer R JR; Lui, Vivian W Y VW; Diergaarde, Brenda B; Maxwell, Jessica H JH; Ferris, Robert L RL; Kim, Seungwon W SW; Luvison, Alyssa A; Miller, Megan M; Nikiforova, Marina N MN

Publication Date: 2013-12-17

Variant appearance in text: PIK3CA: 1571G>A

PubMed Link: 24341335

Variant Present in the following documents:

• Main text
• 1471-2407-13-602.pdf

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Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.

Plos One

Gonzalez-Bosquet, Jesus J; Calcei, Jacob J; Wei, Jun S JS; Garcia-Closas, Montserrat M; Sherman, Mark E ME; Hewitt, Stephen S; Vockley, Joseph J; Lissowska, Jolanta J; Yang, Hannah P HP; Khan, Javed J; Chanock, Stephen S

Publication Date: 2011-01-17

Variant appearance in text: rs104885999

PubMed Link: 21264207

Variant Present in the following documents:

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