PIK3CA c.1618C>G ;(p.L540V)

Variant ID: 3-178936076-C-G

NM_006218.2(PIK3CA):c.1618C>G;(p.L540V)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer.

Jco Precision Oncology
Gerratana, Lorenzo L; Davis, Andrew A AA; Zhang, Qiang Q; Basile, Debora D; Rossi, Giovanna G; Strickland, Kimberly K; Franzoni, Alessandra A; Allegri, Lorenzo L; Mu, Zhaomei Z; Zhang, Youbin Y; Flaum, Lisa E LE; Damante, Giuseppe G; Gradishar, William John WJ; Platanias, Leonidas C LC; Behdad, Amir A; Yang, Hushan H; Puglisi, Fabio F; Cristofanilli, Massimo M
Publication Date: 2021-06

Variant appearance in text: PIK3CA: L540V
PubMed Link: 34136741
Variant Present in the following documents:
  • po-5-943.pdf
View BVdb publication page



Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Nature Communications
Pandey, Akhilesh A; Stawiski, Eric W EW; Durinck, Steffen S; Gowda, Harsha H; Goldstein, Leonard D LD; Barbhuiya, Mustafa A MA; Schröder, Markus S MS; Sreenivasamurthy, Sreelakshmi K SK; Kim, Sun-Whe SW; Phalke, Sameer S; Suryamohan, Kushal K; Lee, Kayla K; Chakraborty, Papia P; Kode, Vasumathi V; Shi, Xiaoshan X; Chatterjee, Aditi A; Datta, Keshava K; Khan, Aafaque A AA; Subbannayya, Tejaswini T; Wang, Jing J; Chaudhuri, Subhra S; Gupta, Sanjiv S; Shrivastav, Braj Raj BR; Jaiswal, Bijay S BS; Poojary, Satish S SS; Bhunia, Shushruta S; Garcia, Patricia P; Bizama, Carolina C; Rosa, Lorena L; Kwon, Wooil W; Kim, Hongbeom H; Han, Youngmin Y; Yadav, Thakur Deen TD; Ramprasad, Vedam L VL; Chaudhuri, Amitabha A; Modrusan, Zora Z; Roa, Juan Carlos JC; Tiwari, Pramod Kumar PK; Jang, Jin-Young JY; Seshagiri, Somasekar S
Publication Date: 2020-08-24

Variant appearance in text: PIK3CA: 1618C>G; L540V
PubMed Link: 32839463
Variant Present in the following documents:
  • 41467_2020_17880_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China.

Cancer Management And Research
Wu, Haibo H; Wang, Wei W; Du, Jun J; Li, Hong H; Wang, Huogang H; Huang, Liangliang L; Xiang, Hang H; Xie, Jing J; Liu, Xiaoli X; Li, Heng H; Lin, Wenchu W
Publication Date: 2019

Variant appearance in text: PIK3CA: 1618C>G
PubMed Link: 30863158
Variant Present in the following documents:
  • Main text
  • cmar-11-1473.pdf
View BVdb publication page



PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer.

Scientific Reports
Mjos, Siv S; Werner, Henrica M J HMJ; Birkeland, Even E; Holst, Frederik F; Berg, Anna A; Halle, Mari K MK; Tangen, Ingvild L IL; Kusonmano, Kanthida K; Mauland, Karen K KK; Oyan, Anne M AM; Kalland, Karl-Henning KH; Lewis, Aurélia E AE; Mills, Gordon B GB; Krakstad, Camilla C; Trovik, Jone J; Salvesen, Helga B HB; Hoivik, Erling A EA
Publication Date: 2017-08-31

Variant appearance in text: PIK3CA: L540V
PubMed Link: 28860563
Variant Present in the following documents:
  • Main text
  • 41598_2017_10717_MOESM1_ESM.pdf
  • 41598_2017_Article_10717.pdf
View BVdb publication page



Polarity gene alterations in pure invasive micropapillary carcinomas of the breast.

Breast Cancer Research : Bcr
Gruel, Nadège N; Benhamo, Vanessa V; Bhalshankar, Jaydutt J; Popova, Tatiana T; Fréneaux, Paul P; Arnould, Laurent L; Mariani, Odette O; Stern, Marc-Henri MH; Raynal, Virginie V; Sastre-Garau, Xavier X; Rouzier, Roman R; Delattre, Olivier O; Vincent-Salomon, Anne A
Publication Date: 2014-05-08

Variant appearance in text: PIK3CA: L540V
PubMed Link: 24887297
Variant Present in the following documents:
  • Main text
  • bcr3653.pdf
View BVdb publication page



Modelling mutational landscapes of human cancers in vitro.

Scientific Reports
Olivier, Magali M; Weninger, Annette A; Ardin, Maude M; Huskova, Hana H; Castells, Xavier X; Vallée, Maxime P MP; McKay, James J; Nedelko, Tatiana T; Muehlbauer, Karl-Rudolf KR; Marusawa, Hiroyuki H; Alexander, John J; Hazelwood, Lee L; Byrnes, Graham G; Hollstein, Monica M; Zavadil, Jiri J
Publication Date: 2014-03-27

Variant appearance in text: PIK3CA: L540V
PubMed Link: 24670820
Variant Present in the following documents:
  • srep04482-s4.xls, sheet 18
View BVdb publication page



Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.

Plos One
Shen, Yinchen Y; Wang, Jianfei J; Han, Xiaohong X; Yang, Hongying H; Wang, Shuai S; Lin, Dongmei D; Shi, Yuankai Y
Publication Date: 2013

Variant appearance in text: PIK3CA: L540V
PubMed Link: 24339949
Variant Present in the following documents:
  • Main text
  • pone.0081628.pdf
View BVdb publication page