Publications:

---

Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.

Cancers

Lim, Malcolm M; Nguyen, Tam H TH; Niland, Colleen C; Reid, Lynne E LE; Jat, Parmjit S PS; Saunus, Jodi M JM; Lakhani, Sunil R SR

Publication Date: 2022-01-21

Variant appearance in text: PIK3CA: K567R

PubMed Link: 35158800

Variant Present in the following documents:

• Main text
• cancers-14-00533.pdf

View BVdb publication page

---

Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.

Cancers

Lim, Malcolm M; Nguyen, Tam H TH; Niland, Colleen C; Reid, Lynne E LE; Jat, Parmjit S PS; Saunus, Jodi M JM; Lakhani, Sunil R SR

Publication Date: 2022-01-21

Variant appearance in text: PIK3CA: K567R

PubMed Link: 35158800

Variant Present in the following documents:

• Main text
• cancers-14-00533.pdf

View BVdb publication page

---

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: PIK3CA: K567R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

---

Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: PIK3CA: K567R

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

---

Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy.

Theranostics

von Baumgarten, Louisa L; Kumbrink, Jörg J; Jung, Andreas A; Reischer, Anna A; Flach, Madeleine M; Liebmann, Sibylle S; Metzeler, Klaus H KH; Holch, Julian W JW; Niyazi, Maximilian M; Thon, Niklas N; Straube, Andreas A; von Bergwelt-Baildon, Michael M; Heinemann, Volker V; Kirchner, Thomas T; Westphalen, Christoph Benedikt CB

Publication Date: 2020

Variant appearance in text: PIK3CA: 1700A>G

PubMed Link: 31903155

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Nature Communications

Menden, Michael P MP; Wang, Dennis D; Mason, Mike J MJ; Szalai, Bence B; Bulusu, Krishna C KC; Guan, Yuanfang Y; Yu, Thomas T; Kang, Jaewoo J; Jeon, Minji M; Wolfinger, Russ R; Nguyen, Tin T; Zaslavskiy, Mikhail M; , ; Jang, In Sock IS; Ghazoui, Zara Z; Ahsen, Mehmet Eren ME; Vogel, Robert R; Neto, Elias Chaibub EC; Norman, Thea T; Tang, Eric K Y EKY; Garnett, Mathew J MJ; Veroli, Giovanni Y Di GYD; Fawell, Stephen S; Stolovitzky, Gustavo G; Guinney, Justin J; Dry, Jonathan R JR; Saez-Rodriguez, Julio J

Publication Date: 2019-06-17

Variant appearance in text: PIK3CA: K567R

PubMed Link: 31209238

Variant Present in the following documents:

• 41467_2019_9799_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Targeting Gas6/TAM in cancer cells and tumor microenvironment.

Molecular Cancer

Wu, Guiling G; Ma, Zhiqiang Z; Cheng, Yicheng Y; Hu, Wei W; Deng, Chao C; Jiang, Shuai S; Li, Tian T; Chen, Fulin F; Yang, Yang Y

Publication Date: 2018-01-31

Variant appearance in text: PI3K: K567R

PubMed Link: 29386018

Variant Present in the following documents:

• Main text
• 12943_2018_Article_769.pdf

View BVdb publication page

---

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: PIK3CA: 1700A>G; K567R

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

---

A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: PIK3CA: 1700A>G; K567R

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

View BVdb publication page

---

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

Molecular Systems Biology

Vizeacoumar, Franco J FJ; Arnold, Roland R; Vizeacoumar, Frederick S FS; Chandrashekhar, Megha M; Buzina, Alla A; Young, Jordan T F JT; Kwan, Julian H M JH; Sayad, Azin A; Mero, Patricia P; Lawo, Steffen S; Tanaka, Hiromasa H; Brown, Kevin R KR; Baryshnikova, Anastasia A; Mak, Anthony B AB; Fedyshyn, Yaroslav Y; Wang, Yadong Y; Brito, Glauber C GC; Kasimer, Dahlia D; Makhnevych, Taras T; Ketela, Troy T; Datti, Alessandro A; Babu, Mohan M; Emili, Andrew A; Pelletier, Laurence L; Wrana, Jeff J; Wainberg, Zev Z; Kim, Philip M PM; Rottapel, Robert R; O'Brien, Catherine A CA; Andrews, Brenda B; Boone, Charles C; Moffat, Jason J

Publication Date: 2013-10-08

Variant appearance in text: PIK3CA: K567R

PubMed Link: 24104479

Variant Present in the following documents:

• msb201354-s13.xlsx, sheet 1

View BVdb publication page

---

mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.

Science Translational Medicine

Elkabets, Moshe M; Vora, Sadhna S; Juric, Dejan D; Morse, Natasha N; Mino-Kenudson, Mari M; Muranen, Taru T; Tao, Jessica J; Campos, Ana Bosch AB; Rodon, Jordi J; Ibrahim, Yasir H YH; Serra, Violeta V; Rodrik-Outmezguine, Vanessa V; Hazra, Saswati S; Singh, Sharat S; Kim, Phillip P; Quadt, Cornelia C; Liu, Manway M; Huang, Alan A; Rosen, Neal N; Engelman, Jeffrey A JA; Scaltriti, Maurizio M; Baselga, José J

Publication Date: 2013-07-31

Variant appearance in text: PIK3CA: K567R

PubMed Link: 23903756

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: K567R

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

---