PIK3CA c.1922A>G ;(p.Y641C)

Variant ID: 3-178937747-A-G

NM_006218.2(PIK3CA):c.1922A>G;(p.Y641C)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders.

Journal Of Medicinal Chemistry
Tomassi, Stefano S; Romanelli, Annalisa A; Zwergel, Clemens C; Valente, Sergio S; Mai, Antonello A
Publication Date: 2021-08-26

Variant appearance in text: PI3K: Y641C
PubMed Link: 34351144
Variant Present in the following documents:
  • jm1c00226.pdf
View BVdb publication page



The Impact of Epigenetic Modifications in Myeloid Malignancies.

International Journal Of Molecular Sciences
Venney, Deirdra D; Mohd-Sarip, Adone A; Mills, Ken I KI
Publication Date: 2021-05-09

Variant appearance in text: PI3K: Y641C
PubMed Link: 34065087
Variant Present in the following documents:
  • Main text
View BVdb publication page



EZH2 abnormalities in lymphoid malignancies: underlying mechanisms and therapeutic implications.

Journal Of Hematology & Oncology
Li, Boheng B; Chng, Wee-Joo WJ
Publication Date: 2019-11-21

Variant appearance in text: PI3K: Y641C
PubMed Link: 31752930
Variant Present in the following documents:
  • Main text
  • 13045_2019_Article_814.pdf
View BVdb publication page



Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review.

Molecular Cancer
Camicia, Rosalba R; Winkler, Hans C HC; Hassa, Paul O PO
Publication Date: 2015-12-11

Variant appearance in text: PI3K: Y641C
PubMed Link: 26654227
Variant Present in the following documents:
  • 12943_2015_Article_474.pdf
View BVdb publication page



Open access chemical probes for epigenetic targets.

Future Medicinal Chemistry
Brown, Peter J PJ; Müller, Susanne S
Publication Date: 2015

Variant appearance in text: PI3K: Y641C
PubMed Link: 26397018
Variant Present in the following documents:
  • emss-66068.pdf
View BVdb publication page



EZH2 and CD79B mutational status over time in B-cell non-Hodgkin lymphomas detected by high-throughput sequencing using minimal samples.

Cancer Cytopathology
Saieg, Mauro Ajaj MA; Geddie, William R WR; Boerner, Scott L SL; Bailey, Denis D; Crump, Michael M; da Cunha Santos, Gilda G
Publication Date: 2013-07

Variant appearance in text: PIK3CA: Y641C
PubMed Link: 23361872
Variant Present in the following documents:
  • cncy0121-0377.pdf
View BVdb publication page