Publications:

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The Prevalence of BRAF, PIK3CA, and RAS Mutations in Indian Patients with Colorectal Cancer.

South Asian Journal Of Cancer

Shetty, Omshree O; Vengurlekar, Vaibhavi V; Kapoor, Akhil A; Kamble, Vishakha V; Gurav, Mamta M; Bhargava, Prabhat P; Srinivas, Sujay S; Ramaswamy, Anant A; Ramadwar, Mukta M; Saklani, Avanish P AP; Desouza, Ashwin A; Ostwal, Vikas V

Publication Date: 2022-07

Variant appearance in text: N/A

PubMed Link: 36620501

Variant Present in the following documents:

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Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis.

International Journal Of Oral Science

Togni, Lucrezia L; Zizzi, Antonio A; Mazzucchelli, Roberta R; Santarelli, Andrea A; Rubini, Corrado C; Mascitti, Marco M

Publication Date: 2022-04-25

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 35468886

Variant Present in the following documents:

• Main text
• 41368_2022_Article_170.pdf

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Frequency of PIK3CA mutations in different subsites of head and neck squamous cell carcinoma in southern Thailand.

Journal Of Pathology And Translational Medicine

Dechaphunkul, Arunee A; Thongwatchara, Phatcharaporn P; Thongsuksai, Paramee P; Dechaphunkul, Tanadech T; Geater, Sarayut Lucien SL

Publication Date: 2022-05

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 35209701

Variant Present in the following documents:

• Main text
• jptm-2022-01-04.pdf

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Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications

Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A

Publication Date: 2021-04-14

Variant appearance in text: PIK3CA: T1025=

PubMed Link: 33854067

Variant Present in the following documents:

• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 9

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Genomic characterization of malignant progression in neoplastic pancreatic cysts.

Nature Communications

Noë, Michaël M; Niknafs, Noushin N; Fischer, Catherine G CG; Hackeng, Wenzel M WM; Beleva Guthrie, Violeta V; Hosoda, Waki W; Debeljak, Marija M; Papp, Eniko E; Adleff, Vilmos V; White, James R JR; Luchini, Claudio C; Pea, Antonio A; Scarpa, Aldo A; Butturini, Giovanni G; Zamboni, Giuseppe G; Castelli, Paola P; Hong, Seung-Mo SM; Yachida, Shinichi S; Hiraoka, Nobuyoshi N; Gill, Anthony J AJ; Samra, Jaswinder S JS; Offerhaus, G Johan A GJA; Hoorens, Anne A; Verheij, Joanne J; Jansen, Casper C; Adsay, N Volkan NV; Jiang, Wei W; Winter, Jordan J; Albores-Saavedra, Jorge J; Terris, Benoit B; Thompson, Elizabeth D ED; Roberts, Nicholas J NJ; Hruban, Ralph H RH; Karchin, Rachel R; Scharpf, Robert B RB; Brosens, Lodewijk A A LAA; Velculescu, Victor E VE; Wood, Laura D LD

Publication Date: 2020-08-14

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 32796935

Variant Present in the following documents:

• 41467_2020_17917_MOESM7_ESM.xlsx, sheet 1

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Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients.

Journal Of Advanced Research

Nassar, Auhood A; Abouelhoda, Mohamed M; Mansour, Osman O; Loutfy, Samah A SA; Hafez, Mohamed M MM; Gomaa, M M; Bahnassy, Abeer A; El-Din Youssef, Amira Salah AS; Lotfy, Mai M MM; Ismail, Hoda H; Ahmed, Ola S OS; Abou-Bakr, Amany Abd-Elhameed AA; Zekri, Abdel-Rahman N AN

Publication Date: 2020-07

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 32322420

Variant Present in the following documents:

• Main text
• main.pdf

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PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane-Based Neoadjuvant Chemotherapy.

Cancer Research And Treatment

Guo, Sanxing S; Loibl, Sibylle S; von Minckwitz, Gunter G; Darb-Esfahani, Silvia S; Lederer, Bianca B; Denkert, Carsten C

Publication Date: 2020-07

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 32019278

Variant Present in the following documents:

• crt-2019-497.pdf

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Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells.

Open Biology

Dunn, Sianadh S; Lombardi, Olivia O; Lukoszek, Radoslaw R; Cowling, Victoria H VH

Publication Date: 2019-04-26

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 30991934

Variant Present in the following documents:

• Main text

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Integrative molecular profiling identifies a novel cluster of estrogen receptor-positive breast cancer in very young women.

Cancer Science

Park, Charny C; Yoon, Kyong-Ah KA; Kim, Jihyun J; Park, In Hae IH; Park, Soo Jin SJ; Kim, Min Kyeong MK; Jang, Wooyeong W; Cho, Soo Young SY; Park, Boyoung B; Kong, Sun-Young SY; Lee, Eun Sook ES

Publication Date: 2019-05

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 30811755

Variant Present in the following documents:

• CAS-110-1760-s002.xlsx, sheet 2

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

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Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.

British Journal Of Cancer

Mariani, Sara S; Bertero, Luca L; Osella-Abate, Simona S; Di Bello, Cristiana C; Francia di Celle, Paola P; Coppola, Vittoria V; Sapino, Anna A; Cassoni, Paola P; Marchiò, Caterina C

Publication Date: 2017-07-25

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 28618430

Variant Present in the following documents:

• bjc2017170a.pdf

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Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: N/A

PubMed Link: 28569743

Variant Present in the following documents:

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: PI3K: 3075C>A; T1025T

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.

Gut

Sievers, Chelsie K CK; Zou, Luli S LS; Pickhardt, Perry J PJ; Matkowskyj, Kristina A KA; Albrecht, Dawn M DM; Clipson, Linda L; Bacher, Jeffery W JW; Pooler, B Dustin BD; Moawad, Fouad J FJ; Cash, Brooks D BD; Reichelderfer, Mark M; Vo, Tien N TN; Newton, Michael A MA; Larget, Bret R BR; Halberg, Richard B RB

Publication Date: 2017-12

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 27609830

Variant Present in the following documents:

• gutjnl-2016-312232supp003.pdf

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The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

Bmc Bioinformatics

Pagan, Moraima M; Kloos, Richard T RT; Lin, Chu-Fang CF; Travers, Kevin J KJ; Matsuzaki, Hajime H; Tom, Ed Y EY; Kim, Su Yeon SY; Wong, Mei G MG; Stewart, Andrew C AC; Huang, Jing J; Walsh, P Sean PS; Monroe, Robert J RJ; Kennedy, Giulia C GC

Publication Date: 2016-01-11

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 26818556

Variant Present in the following documents:

• 12859_2015_849_MOESM5_ESM.pdf

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Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.

Cancer Research

Dogruluk, Turgut T; Tsang, Yiu Huen YH; Espitia, Maribel M; Chen, Fengju F; Chen, Tenghui T; Chong, Zechen Z; Appadurai, Vivek V; Dogruluk, Armel A; Eterovic, Agna Karina AK; Bonnen, Penelope E PE; Creighton, Chad J CJ; Chen, Ken K; Mills, Gordon B GB; Scott, Kenneth L KL

Publication Date: 2015-12-15

Variant appearance in text: N/A

PubMed Link: 26627007

Variant Present in the following documents:

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A functional variant at miR-520a binding site in PIK3CA alters susceptibility to colorectal cancer in a Chinese Han population.

Biomed Research International

Ding, Lifang L; Jiang, Zao Z; Chen, Qiaoyun Q; Qin, Rong R; Fang, Yue Y; Li, Hao H

Publication Date: 2015

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 25834816

Variant Present in the following documents:

• Main text
• BMRI2015-373252.pdf

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PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients.

Clinics (Sao Paulo, Brazil)

Mangone, Flavia R FR; Bobrovnitchaia, Irina G IG; Salaorni, Sibeli S; Manuli, Erika E; Nagai, Maria A MA

Publication Date: 2012-11

Variant appearance in text: PIK3CA: T1025T

PubMed Link: 23184205

Variant Present in the following documents:

• Main text

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