Variant ID: 3-178952085-A-G

NM_006218.2(PIK3CA):c.3140A>G;(p.H1047R)

This variant was identified in 2547 publications

View GRCh38 version.




Publications:


Corticosteroid-Refractory Myositis After Dual BRAF and MEK Inhibition in a Patient with BRAF V600E-Mutant Metastatic Intrahepatic Cholangiocarcinoma.

Journal Of Immunotherapy And Precision Oncology
DiPeri, Timothy P TP; Demirhan, Mehmet M; Karp, Daniel D DD; Fu, Siqing S; Hong, David S DS; Subbiah, Vivek V; Lim, Joann J; Ballester, Leomar Y LY; Tayar, Jean H JH; Suarez-Almazor, Maria E ME; Javle, Milind M; Meric-Bernstam, Funda F
Publication Date: 2022-02

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35663835
Variant Present in the following documents:
  • Main text
  • i2590-017X-5-1-26.pdf
View BVdb publication page



Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer.

Journal Of Experimental & Clinical Cancer Research : Cr
Yang, Lu L; Bhattacharya, Arup A; Li, Yun Y; Sexton, Sandra S; Ling, Xiang X; Li, Fengzhi F; Zhang, Yuesheng Y
Publication Date: 2022-06-02

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35650607
Variant Present in the following documents:
  • Main text
  • 13046_2022_Article_2389.pdf
View BVdb publication page



Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.

Acta Neuropathologica Communications
Arunachalam, Sasi S; Szlachta, Karol K; Brady, Samuel W SW; Ma, Xiaotu X; Ju, Bensheng B; Shaner, Bridget B; Mulder, Heather L HL; Easton, John J; Raphael, Benjamin J BJ; Myers, Matthew M; Tinkle, Christopher C; Allen, Sariah J SJ; Orr, Brent A BA; Wetmore, Cynthia J CJ; Baker, Suzanne J SJ; Zhang, Jinghui J
Publication Date: 2022-05-31

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35642016
Variant Present in the following documents:
  • Main text
  • 40478_2022_Article_1381.pdf
  • 40478_2022_1381_MOESM2_ESM.pdf
View BVdb publication page



Comprehensive Characterization of the Genomic Landscape in Chinese Pulmonary Neuroendocrine Tumors Reveals Prognostic and Therapeutic Markers (CSWOG-1901).

The Oncologist
Peng, Wenying W; Cao, Liming L; Chen, Likun L; Lin, Gen G; Zhu, Bo B; Hu, Xiaohua X; Lin, Yingcheng Y; Zhang, Sheng S; Jiang, Meilin M; Wang, Jingyi J; Li, Junjun J; Li, Chao C; Shao, Lin L; Du, Haiwei H; Hou, Ting T; Chen, Zhiqiu Z; Xiang, Jianxing J; Pu, Xingxiang X; Li, Jia J; Xu, Fang F; Loong, Herbert H; Wu, Lin L
Publication Date: 2022-03-04

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35641209
Variant Present in the following documents:
  • Main text
  • oyab044.pdf
View BVdb publication page



Disentangling ERBB Signaling in Breast Cancer Subtypes-A Model-Based Analysis.

Cancers
Kemmer, Svenja S; Berdiel-Acer, Mireia M; Reinz, Eileen E; Sonntag, Johanna J; Tarade, Nooraldeen N; Bernhardt, Stephan S; Fehling-Kaschek, Mirjam M; Hasmann, Max M; Korf, Ulrike U; Wiemann, Stefan S; Timmer, Jens J
Publication Date: 2022-05-12

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35625984
Variant Present in the following documents:
  • Main text
  • cancers-14-02379.pdf
View BVdb publication page



Wide Next-Generation Sequencing Characterization of Young Adults Non-Small-Cell Lung Cancer Patients.

Cancers
Ulivi, Paola P; Urbini, Milena M; Petracci, Elisabetta E; Canale, Matteo M; Dubini, Alessandra A; Bartolini, Daniela D; Calistri, Daniele D; Cravero, Paola P; Fonzi, Eugenio E; Martinelli, Giovanni G; Priano, Ilaria I; Andrikou, Kalliopi K; Bronte, Giuseppe G; Crinò, Lucio L; Delmonte, Angelo A
Publication Date: 2022-05-10

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35625958
Variant Present in the following documents:
  • Main text
  • cancers-14-02352.pdf
View BVdb publication page



Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome.

Biomolecules
Rangwala, Aziz M AM; Mingione, Victoria R VR; Georghiou, George G; Seeliger, Markus A MA
Publication Date: 2022-05-11

Variant appearance in text: PI3K: H1047R
PubMed Link: 35625613
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00685.pdf
View BVdb publication page



PIK3CA Mutation as Potential Poor Prognostic Marker in Asian Female Breast Cancer Patients Who Received Adjuvant Chemotherapy.

Current Oncology (Toronto, Ont.)
Cho, Yoon Ah YA; Ko, Seung Yeon SY; Suh, Yong Joon YJ; Kim, Sanghwa S; Park, Jung Ho JH; Park, Hye-Rim HR; Seo, Jinwon J; Choi, Hyo Geun HG; Kang, Ho Suk HS; Lim, Hyun H; Park, Ha Young HY; Kwon, Mi Jung MJ
Publication Date: 2022-04-19

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35621626
Variant Present in the following documents:
  • Main text
  • curroncol-29-00236.pdf
View BVdb publication page



PIK3CA mutations-mediated downregulation of circLHFPL2 inhibits colorectal cancer progression via upregulating PTEN.

Molecular Cancer
Chong, Xiaodan X; Chen, Jingde J; Zheng, Nanxin N; Zhou, Zhuqing Z; Hai, Yanan Y; Chen, Shiqing S; Zhang, Yu Y; Yu, Qingzhuo Q; Yu, Shijun S; Chen, Zhiqin Z; Bao, Wenfang W; Quan, Ming M; Chen, Zhe-Sheng ZS; Zhan, Yangyang Y; Gao, Yong Y
Publication Date: 2022-05-26

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35619132
Variant Present in the following documents:
  • Main text
  • 12943_2022_Article_1531.pdf
View BVdb publication page



Lab-on-chip assay of tumour markers and human papilloma virus for cervical cancer detection at the point-of-care.

Scientific Reports
Wormald, Benjamin W BW; Moser, Nicolas N; deSouza, Nandita M NM; Mantikas, Katerina-Theresa KT; Malpartida-Cardenas, Kenny K; Pennisi, Ivana I; Ind, Thomas E J TEJ; Vroobel, Katherine K; Kalofonou, Melpomeni M; Rodriguez-Manzano, Jesus J; Georgiou, Pantelis P
Publication Date: 2022-05-24

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35610285
Variant Present in the following documents:
  • 41598_2022_Article_12557.pdf
View BVdb publication page



Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma.

Clinical And Translational Medicine
Xing, Hui H; Gao, Mengshi M; Wang, Yuxiang Y; Zhang, Xu X; Shi, Jiajie J; Wang, Xiang X; Liu, Xueling X; Ma, Qingyang Q; Kong, Xiangyin X; Yang, Chunhao C; Ding, Jian J; Meng, Linghua L
Publication Date: 2022-05

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35604910
Variant Present in the following documents:
  • CTM2-12-e835.pdf
View BVdb publication page



Resistance to ERK1/2 pathway inhibitors; sweet spots, fitness deficits and drug addiction.

Cancer Drug Resistance (Alhambra, Calif.)
Sale, Matthew J MJ; Balmanno, Kathryn K; Cook, Simon J SJ
Publication Date: 2019

Variant appearance in text: PI3K: H1047R
PubMed Link: 35582726
Variant Present in the following documents:
  • cdr-2-365.pdf
View BVdb publication page



Mechanistic target of rapamycin inhibitors: successes and challenges as cancer therapeutics.

Cancer Drug Resistance (Alhambra, Calif.)
Bhaoighill, Muireann Ní MN; Dunlop, Elaine A EA
Publication Date: 2019

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35582282
Variant Present in the following documents:
  • cdr-2-1069.pdf
View BVdb publication page



Network rewiring, adaptive resistance and combating strategies in breast cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Cremers, Constance Gaya CG; Nguyen, Lan K LK
Publication Date: 2019

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35582276
Variant Present in the following documents:
  • cdr-2-1106.pdf
View BVdb publication page



Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Nature Communications
Lee, Bernard C H BCH; Robinson, Philip S PS; Coorens, Tim H H THH; Yan, Helen H N HHN; Olafsson, Sigurgeir S; Lee-Six, Henry H; Sanders, Mathijs A MA; Siu, Hoi Cheong HC; Hewinson, James J; Yue, Sarah S K SSK; Tsui, Wai Yin WY; Chan, Annie S Y ASY; Chan, Anthony K W AKW; Ho, Siu Lun SL; Campbell, Peter J PJ; Martincorena, Inigo I; Buczacki, Simon J A SJA; Yuen, Siu Tsan ST; Leung, Suet Yi SY; Stratton, Michael R MR
Publication Date: 2022-05-17

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35581206
Variant Present in the following documents:
  • 41467_2022_29920_MOESM3_ESM.xlsx
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



Potential Biomarkers of Skin Melanoma Resistance to Targeted Therapy-Present State and Perspectives.

Cancers
Olbryt, Magdalena M
Publication Date: 2022-05-06

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35565444
Variant Present in the following documents:
  • cancers-14-02315.pdf
View BVdb publication page



Clinical Significance of Molecular Alterations and Systemic Therapy for Meningiomas: Where Do We Stand?

Cancers
Pellerino, Alessia A; Bruno, Francesco F; Palmiero, Rosa R; Pronello, Edoardo E; Bertero, Luca L; Soffietti, Riccardo R; Rudà, Roberta R
Publication Date: 2022-04-30

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35565385
Variant Present in the following documents:
  • cancers-14-02256.pdf
View BVdb publication page



Tumour Stem Cells in Breast Cancer.

International Journal Of Molecular Sciences
Ibragimova, Marina M; Tsyganov, Matvey M; Litviakov, Nikolai N
Publication Date: 2022-05-02

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35563449
Variant Present in the following documents:
  • ijms-23-05058.pdf
View BVdb publication page



CfDNA Measurement as a Diagnostic Tool for the Detection of Brain Somatic Mutations in Refractory Epilepsy.

International Journal Of Molecular Sciences
Mayo, Sonia S; Gómez-Manjón, Irene I; Fernández-Martínez, Francisco Javier FJ; Camacho, Ana A; Martínez, Francisco F; Benito-León, Julián J
Publication Date: 2022-04-28

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35563270
Variant Present in the following documents:
  • ijms-23-04879.pdf
View BVdb publication page



Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma.

Bmc Medicine
Gu, Ziyue Z; Shi, Chaoji C; Li, Jiayi J; Han, Yong Y; Sun, Bao B; Zhang, Wuchang W; Wu, Jing J; Zhou, Guoyu G; Ye, Weimin W; Li, Jiang J; Zhang, Zhiyuan Z; Zhou, Rong R
Publication Date: 2022-05-12

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35546399
Variant Present in the following documents:
  • 12916_2022_2373_MOESM2_ESM.xlsx
View BVdb publication page



Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))
Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L
Publication Date: 2022-05-10

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35509869
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA.

Plos One
Poh, Jonathan J; Ngeow, Kao Chin KC; Pek, Michelle M; Tan, Kian-Hin KH; Lim, Jing Shan JS; Chen, Hao H; Ong, Choon Kiat CK; Lim, Jing Quan JQ; Lim, Soon Thye ST; Lim, Chwee Ming CM; Goh, Boon Cher BC; Choudhury, Yukti Y
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35486650
Variant Present in the following documents:
  • pone.0267389.pdf
  • pone.0267389.s008.xlsx
View BVdb publication page



Distinct clinical and somatic mutational features of breast tumors with high-, low-, or non-expressing human epidermal growth factor receptor 2 status.

Bmc Medicine
Zhang, Guochun G; Ren, Chongyang C; Li, Cheukfai C; Wang, Yulei Y; Chen, Bo B; Wen, Lingzhu L; Jia, Minghan M; Li, Kai K; Mok, Hsiaopei H; Cao, Li L; Chen, Xiaoqing X; Lin, Jiali J; Wei, Guangnan G; Li, Yingzhi Y; Zhang, Yuchen Y; Balch, Charles M CM; Liao, Ning N
Publication Date: 2022-04-29

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35484593
Variant Present in the following documents:
  • 12916_2022_Article_2346.pdf
View BVdb publication page



Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.

Nature Medicine
Chandran, Smita S SS; Ma, Jiaqi J; Klatt, Martin G MG; Dündar, Friederike F; Bandlamudi, Chaitanya C; Razavi, Pedram P; Wen, Hannah Y HY; Weigelt, Britta B; Zumbo, Paul P; Fu, Si Ning SN; Banks, Lauren B LB; Yi, Fei F; Vercher, Enric E; Etxeberria, Inaki I; Bestman, Watchain D WD; Da Cruz Paula, Arnaud A; Aricescu, Ilinca S IS; Drilon, Alexander A; Betel, Doron D; Scheinberg, David A DA; Baker, Brian M BM; Klebanoff, Christopher A CA
Publication Date: 2022-04-28

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35484264
Variant Present in the following documents:
  • 41591_2022_Article_1786.pdf
View BVdb publication page



The utility of cerebrospinal fluid-derived cell-free DNA in molecular diagnostics for the PIK3CA-related megalencephaly-capillary malformation (MCAP) syndrome: a case report.

Cold Spring Harbor Molecular Case Studies
Chen, Wei-Liang WL; Pao, Emily E; Owens, James J; Glass, Ian I; Pritchard, Colin C; Shirts, Brain H BH; Lockwood, Christina C; Mirzaa, Ghayda M GM
Publication Date: 2022-04

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35483878
Variant Present in the following documents:
  • MCS006188Che.pdf
View BVdb publication page



Baseline Mutations and Up-Regulation of PI3K-AKT Pathway Serve as Potential Indicators of Lack of Response to Neoadjuvant Chemotherapy in Stage II/III Breast Cancer.

Frontiers In Oncology
Dong, Menghao M; Shan, Benjie B; Han, Xinghua X; Zhao, Xiaotian X; Wang, Fufeng F; Zhu, Liuqing L; Ou, Qiuxiang Q; Ma, Xiaopeng X; Pan, Yueyin Y
Publication Date: 2021

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35480699
Variant Present in the following documents:
  • fonc-11-784985.pdf
View BVdb publication page



Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.

American Journal Of Human Genetics
Palles, Claire C; West, Hannah D HD; Chew, Edward E; Galavotti, Sara S; Flensburg, Christoffer C; Grolleman, Judith E JE; Jansen, Erik A M EAM; Curley, Helen H; Chegwidden, Laura L; Arbe-Barnes, Edward H EH; Lander, Nicola N; Truscott, Rebekah R; Pagan, Judith J; Bajel, Ashish A; Sherwood, Kitty K; Martin, Lynn L; Thomas, Huw H; Georgiou, Demetra D; Fostira, Florentia F; Goldberg, Yael Y; Adams, David J DJ; van der Biezen, Simone A M SAM; Christie, Michael M; Clendenning, Mark M; Thomas, Laura E LE; Deltas, Constantinos C; Dimovski, Aleksandar J AJ; Dymerska, Dagmara D; Lubinski, Jan J; Mahmood, Khalid K; van der Post, Rachel S RS; Sanders, Mathijs M; Weitz, Jürgen J; Taylor, Jenny C JC; Turnbull, Clare C; Vreede, Lilian L; van Wezel, Tom T; Whalley, Celina C; Arnedo-Pac, Claudia C; Caravagna, Giulio G; Cross, William W; Chubb, Daniel D; Frangou, Anna A; Gruber, Andreas J AJ; Kinnersley, Ben B; Noyvert, Boris B; Church, David D; Graham, Trevor T; Houlston, Richard R; Lopez-Bigas, Nuria N; Sottoriva, Andrea A; Wedge, David D; , ; , ; , ; Jenkins, Mark A MA; Kuiper, Roland P RP; Roberts, Andrew W AW; Cheadle, Jeremy P JP; Ligtenberg, Marjolijn J L MJL; Hoogerbrugge, Nicoline N; Koelzer, Viktor H VH; Rivas, Andres Dacal AD; Winship, Ingrid M IM; Ponte, Clara Ruiz CR; Buchanan, Daniel D DD; Power, Derek G DG; Green, Andrew A; Tomlinson, Ian P M IPM; Sampson, Julian R JR; Majewski, Ian J IJ; de Voer, Richarda M RM
Publication Date: 2022-04-20

Variant appearance in text: PIK3CA: 3140A>G; His1047Arg
PubMed Link: 35460607
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



A Systematic Review of Atypical Endometriosis-Associated Biomarkers.

International Journal Of Molecular Sciences
Bartiromo, Ludovica L; Schimberni, Matteo M; Villanacci, Roberta R; Mangili, Giorgia G; Ferrari, Stefano S; Ottolina, Jessica J; Salmeri, Noemi N; Dolci, Carolina C; Tandoi, Iacopo I; Candiani, Massimo M
Publication Date: 2022-04-17

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35457244
Variant Present in the following documents:
  • ijms-23-04425.pdf
View BVdb publication page



KRAS: A Druggable Target in Colon Cancer Patients.

International Journal Of Molecular Sciences
Negri, Francesca F; Bottarelli, Lorena L; de'Angelis, Gian Luigi GL; Gnetti, Letizia L
Publication Date: 2022-04-08

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35456940
Variant Present in the following documents:
  • ijms-23-04120.pdf
View BVdb publication page



Acquired Mechanisms of Resistance to Osimertinib-The Next Challenge.

Cancers
Ríos-Hoyo, Alejandro A; Moliner, Laura L; Arriola, Edurne E
Publication Date: 2022-04-12

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35454838
Variant Present in the following documents:
  • cancers-14-01931.pdf
View BVdb publication page



Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients.

Npj Breast Cancer
Hu, Li L; Sun, Jie J; Li, Zhongwu Z; Qu, Ziwei Z; Liu, Yan Y; Wan, Qiting Q; Liu, Jiaming J; Ding, Xinyun X; Zang, Fan F; Zhang, Juan J; Yao, Lu L; Xu, Ye Y; Wang, Yin Y; Xie, Yuntao Y
Publication Date: 2022-04-21

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35449176
Variant Present in the following documents:
  • 41523_2022_417_MOESM3_ESM.xlsx
View BVdb publication page



Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

Plos One
Shi, Zonggao Z; Lopez, Jacqueline J; Kalliney, William W; Sutton, Bobbie B; Simpson, Joyce J; Maggert, Kevin K; Liu, Sheng S; Wan, Jun J; Stack, M Sharon MS
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35446881
Variant Present in the following documents:
  • pone.0266914.pdf
View BVdb publication page



Nuclear translocation of p85β promotes tumorigenesis of PIK3CA helical domain mutant cancer.

Nature Communications
Hao, Yujun Y; He, Baoyu B; Wu, Liping L; Li, Yamu Y; Wang, Chao C; Wang, Ting T; Sun, Longci L; Zhang, Yanhua Y; Zhan, Yangyang Y; Zhao, Yiqing Y; Markowitz, Sanford S; Veigl, Martina M; Conlon, Ronald A RA; Wang, Zhenghe Z
Publication Date: 2022-04-13

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35418124
Variant Present in the following documents:
  • 41467_2022_Article_29585.pdf
  • 41467_2022_29585_MOESM1_ESM.pdf
  • 41467_2022_29585_MOESM2_ESM.pdf
View BVdb publication page



TMT-Based Multiplexed Quantitation of N-Glycopeptides Reveals Glycoproteome Remodeling Induced by Oncogenic Mutations.

Acs Omega
Saraswat, Mayank M; Mangalaparthi, Kiran Kumar KK; Garapati, Kishore K; Pandey, Akhilesh A
Publication Date: 2022-04-05

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35415375
Variant Present in the following documents:
  • ao1c06970.pdf
View BVdb publication page



COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2.

International Journal Of Biological Sciences
Zhang, Lianmei L; Wei, Chunli C; Li, Dabing D; He, Jiayue J; Liu, Shuguang S; Deng, Haoyue H; Cheng, Jingliang J; Du, Jiaman J; Liu, Xiaoyan X; Chen, Hanchun H; Sun, Suan S; Yu, Hong H; Fu, Junjiang J
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35414771
Variant Present in the following documents:
  • ijbsv18p2362.pdf
View BVdb publication page



Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies.

International Journal Of Molecular Sciences
Shetu, Shaila A SA; Bandyopadhyay, Debasish D
Publication Date: 2022-03-28

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35409064
Variant Present in the following documents:
  • ijms-23-03706.pdf
View BVdb publication page



Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Frontiers In Oncology
Kyrochristos, Ioannis D ID; Glantzounis, Georgios K GK; Goussia, Anna A; Eliades, Alexia A; Achilleos, Achilleas A; Tsangaras, Kyriakos K; Hadjidemetriou, Irene I; Elpidorou, Marilena M; Ioannides, Marios M; Koumbaris, George G; Mitsis, Michail M; Patsalis, Philippos C PC; Roukos, Dimitrios D
Publication Date: 2022

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35402285
Variant Present in the following documents:
  • Table_1.xlsx
View BVdb publication page



PI3K/Akt/mTOR Pathway and Its Role in Cancer Therapeutics: Are We Making Headway?

Frontiers In Oncology
Peng, Yan Y; Wang, Yuanyuan Y; Zhou, Cheng C; Mei, Wuxuan W; Zeng, Changchun C
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35402264
Variant Present in the following documents:
  • fonc-12-819128.pdf
View BVdb publication page



Clinicopathologic and Genomic Features in Triple-Negative Breast Cancer Between Special and No-Special Morphologic Pattern.

Frontiers In Oncology
Li, Ying-Zi YZ; Chen, Bo B; Lin, Xiao-Yi XY; Zhang, Guo-Chun GC; Lai, Jian-Guo JG; Li, Cheukfai C; Lin, Jia-Li JL; Guo, Li-Ping LP; Xiao, Wei-Kai WK; Mok, Hsiaopei H; Ren, Chong-Yang CY; Wen, Ling-Zhu LZ; Cao, Fang-Rong FR; Lin, Xin X; Qi, Xiao-Fang XF; Liu, Yang Y; Liao, Ning N
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35402236
Variant Present in the following documents:
  • fonc-12-830124.pdf
View BVdb publication page



Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)
Zhu, Haichuan H; Dong, Bingjie B; Zhang, Yingchi Y; Wang, Mei M; Rao, Jianan J; Cui, Bowen B; Liu, Yu Y; Jiang, Qian Q; Wang, Weitao W; Yang, Lu L; Yu, Anqi A; Li, Zongru Z; Liu, Chao C; Zhang, Leping L; Huang, Xiaojun X; Zhu, Xiaofan X; Wu, Hong H
Publication Date: 2022-01

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35399540
Variant Present in the following documents:
  • bls-4-16-s005.xlsx
View BVdb publication page



A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets.

Frontiers In Oncology
Zhou, Si S; Liu, Songming S; Zhao, Lijian L; Sun, Hai-Xi HX
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35387130
Variant Present in the following documents:
  • fonc-12-786438.pdf
  • Table_2.xlsx
View BVdb publication page



Genomic clonal evolution correlated with phenotype and prognosis in gastric cancer.

Clinical And Translational Medicine
Ge, Jie J; Li, Xuan X; Deng, Zhenghao Z; Gao, Xuan X; Liu, Yaoyao Y; Xiong, Xingui X; Zhao, Xianhui X; Peng, Huan H; Yi, Xin X; Xia, Xuefeng X; Chen, Zihua Z; Li, Lifeng L; Zhou, Haiyan H; Liu, Heli H
Publication Date: 2022-04

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35384329
Variant Present in the following documents:
  • CTM2-12-e799-s006.xlsx
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Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells.

Bmc Cancer
Chauvin, Anaïs A; Bergeron, Danny D; Vencic, Jean J; Lévesque, Dominique D; Paquette, Benoit B; Scott, Michelle S MS; Boisvert, François-Michel FM
Publication Date: 2022-04-04

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35379199
Variant Present in the following documents:
  • 12885_2022_Article_9417.pdf
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Somatic activating BRAF variants cause isolated lymphatic malformations.

Hgg Advances
Zenner, Kaitlyn K; Jensen, Dana M DM; Dmyterko, Victoria V; Shivaram, Giridhar M GM; Myers, Candace T CT; Paschal, Cate R CR; Rudzinski, Erin R ER; Pham, Minh-Hang M MM; Cheng, V Chi VC; Manning, Scott C SC; Bly, Randall A RA; Ganti, Sheila S; Perkins, Jonathan A JA; Bennett, James T JT
Publication Date: 2022-04-14

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35373151
Variant Present in the following documents:
  • mmc1.pdf
  • main.pdf
  • mmc2.pdf
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Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.

Breast Cancer Research : Bcr
Heynen, Guus J J E GJJE; Lisek, Kamil K; Vogel, Regina R; Wulf-Goldenberg, Annika A; Alcaniz, Joshua J; Montaudon, Elodie E; Marangoni, Elisabetta E; Birchmeier, Walter W
Publication Date: 2022-04-01

Variant appearance in text: PI3K: H1047R
PubMed Link: 35365185
Variant Present in the following documents:
  • 13058_2022_Article_1521.pdf
  • 13058_2022_1521_MOESM1_ESM.pdf
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Nanomaterial-Based Immunocapture Platforms for the Recognition, Isolation, and Detection of Circulating Tumor Cells.

Frontiers In Bioengineering And Biotechnology
Liu, Yichao Y; Li, Rui R; Zhang, Lingling L; Guo, Shishang S
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35360401
Variant Present in the following documents:
  • fbioe-10-850241.pdf
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Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One
Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35358259
Variant Present in the following documents:
  • pone.0266112.pdf
  • pone.0266112.s001.xlsx
View BVdb publication page



PIK3CA Mutations Drive Therapeutic Resistance in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.

Jco Precision Oncology
Rasti, Aryana R AR; Guimaraes-Young, Amy A; Datko, Farrah F; Borges, Virginia F VF; Aisner, Dara L DL; Shagisultanova, Elena E
Publication Date: 2022-03

Variant appearance in text: PI3K: H1047R
PubMed Link: 35357905
Variant Present in the following documents:
  • po-6-e2100370.pdf
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Drug Discovery of Plausible Lead Natural Compounds That Target the Insulin Signaling Pathway: Bioinformatics Approaches.

Evidence-Based Complementary And Alternative Medicine : Ecam
Shanak, Siba S; Bassalat, Najlaa N; Barghash, Ahmad A; Kadan, Sleman S; Ardah, Mahmoud M; Zaid, Hilal H
Publication Date: 2022

Variant appearance in text: PI3K: H1047R
PubMed Link: 35356248
Variant Present in the following documents:
  • ECAM2022-2832889.pdf
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Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα.

Journal Of The American Chemical Society
Borsari, Chiara C; Keles, Erhan E; McPhail, Jacob A JA; Schaefer, Alexander A; Sriramaratnam, Rohitha R; Goch, Wojciech W; Schaefer, Thorsten T; De Pascale, Martina M; Bal, Wojciech W; Gstaiger, Matthias M; Burke, John E JE; Wymann, Matthias P MP
Publication Date: 2022-03-30

Variant appearance in text: PIK3CA: His1047Arg
PubMed Link: 35353516
Variant Present in the following documents:
  • ja1c13568.pdf
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The PIK3CA H1047R Mutation Confers Resistance to BRAF and MEK Inhibitors in A375 Melanoma Cells through the Cross-Activation of MAPK and PI3K-Akt Pathways.

Pharmaceutics
Candido, Saverio S; Salemi, Rossella R; Piccinin, Sara S; Falzone, Luca L; Libra, Massimo M
Publication Date: 2022-03-08

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35335966
Variant Present in the following documents:
  • pharmaceutics-14-00590.pdf
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Evolution of Protein Functional Annotation: Text Mining Study.

Journal Of Personalized Medicine
Ilgisonis, Ekaterina V EV; Pogodin, Pavel V PV; Kiseleva, Olga I OI; Tarbeeva, Svetlana N SN; Ponomarenko, Elena A EA
Publication Date: 2022-03-16

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35330478
Variant Present in the following documents:
  • jpm-12-00479.pdf
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Systemic Treatments for Advanced Small Bowel Adenocarcinoma: A Systematic Review.

Cancers
Di Nardo, Paola P; Garattini, Silvio Ken SK; Torrisi, Elena E; Fanotto, Valentina V; Miolo, Gianmaria G; Buonadonna, Angela A; Puglisi, Fabio F
Publication Date: 2022-03-15

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35326652
Variant Present in the following documents:
  • cancers-14-01502.pdf
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Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

Plos One
Williams, Gareth G; Llewelyn, Alexander A; Thatcher, Robert R; Hardisty, Keeda-Marie KM; Loddo, Marco M
Publication Date: 2022

Variant appearance in text: PIK3CA: 3140A>G; His1047Arg; rs121913279
PubMed Link: 35324914
Variant Present in the following documents:
  • pone.0245817.s005.pdf
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Clinical significance of molecular subtypes of gastrointestinal tract adenocarcinoma.

World Journal Of Gastrointestinal Oncology
Ignatova, Ekaterina Olegovna EO; Kozlov, Evgenii E; Ivanov, Maxim M; Mileyko, Vladislav V; Menshikova, Sofia S; Sun, Henian H; Fedyanin, Mikhail M; Tryakin, Alexey A; Stilidi, Ivan I
Publication Date: 2022-03-15

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35321271
Variant Present in the following documents:
  • WJGO-14-628.pdf
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S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions.

Nature Communications
Jiang, Qiwei Q; Zhang, Xiaomei X; Dai, Xiaoming X; Han, Shiyao S; Wu, Xueji X; Wang, Lei L; Wei, Wenyi W; Zhang, Ning N; Xie, Wei W; Guo, Jianping J
Publication Date: 2022-03-22

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35318320
Variant Present in the following documents:
  • 41467_2022_28910_MOESM2_ESM.pdf
View BVdb publication page



AKT1 and PIK3CA activating mutations in Moroccan bladder cancer patients´ biopsies and matched urine.

The Pan African Medical Journal
El Ahanidi, Hajar H; El Azzouzi, Meryem M; Arrouchi, Housna H; Alaoui, Chaimae Hafidi CH; Tetou, Mohammed M; Bensaid, Mounia M; Oukabli, Mohamed M; Ameur, Ahmed A; Al Bouzidi, Abderrahmane A; El Mzibri, Mohammed M; Attaleb, Mohammed M
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35317488
Variant Present in the following documents:
  • PAMJ-41-59.pdf
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Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer.

Molecular Biomedicine
Ruan, Hang H; Leibowitz, Brian J BJ; Peng, Yingpeng Y; Shen, Lin L; Chen, Lujia L; Kuang, Charlie C; Schoen, Robert E RE; Lu, Xinghua X; Zhang, Lin L; Yu, Jian J
Publication Date: 2022-03-21

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35307764
Variant Present in the following documents:
  • 43556_2022_70_MOESM1_ESM.pdf
View BVdb publication page



Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine
Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J
Publication Date: 2022-03-17

Variant appearance in text: N/A
PubMed Link: 35306340
Variant Present in the following documents:
View BVdb publication page



Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer.

Scientific Reports
Tan, Winston W; Zheng, Tiantian T; Wang, Amy A; Roacho, Joanna J; Thao, Seng S; Du, Pan P; Jia, Shidong S; Yu, Jianjun J; King, Bonnie L BL; Kohli, Manish M
Publication Date: 2022-03-18

Variant appearance in text: PIK3CA: 3140A>G; His1047Arg
PubMed Link: 35304525
Variant Present in the following documents:
  • 41598_2022_8520_MOESM2_ESM.xlsx
View BVdb publication page



p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases.

Nature Communications
Ni, Jing J; Kabraji, Sheheryar S; Xie, Shaozhen S; Wang, Yanzhi Y; Pan, Peichen P; He, Xiaofang X; Liu, Zongming Z; Leone, Jose Palbo JP; Long, Henry W HW; Brown, Myles A MA; Winer, Eric P EP; Dillon, Deborah A R DAR; Lin, Nancy U NU; Zhao, Jean J JJ
Publication Date: 2022-03-18

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35304445
Variant Present in the following documents:
  • 41467_2022_29081_MOESM3_ESM.xlsx
View BVdb publication page



Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors.

Plos One
Milbury, Coren A CA; Creeden, James J; Yip, Wai-Ki WK; Smith, David L DL; Pattani, Varun V; Maxwell, Kristi K; Sawchyn, Bethany B; Gjoerup, Ole O; Meng, Wei W; Skoletsky, Joel J; Concepcion, Alvin D AD; Tang, Yanhua Y; Bai, Xiaobo X; Dewal, Ninad N; Ma, Pei P; Bailey, Shannon T ST; Thornton, James J; Pavlick, Dean C DC; Frampton, Garrett M GM; Lieber, Daniel D; White, Jared J; Burns, Christine C; Vietz, Christine C
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35294956
Variant Present in the following documents:
  • pone.0264138.pdf
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Genetics and Epigenetics of Parathyroid Carcinoma.

Frontiers In Endocrinology
Marini, Francesca F; Giusti, Francesca F; Palmini, Gaia G; Perigli, Giuliano G; Santoro, Roberto R; Brandi, Maria Luisa ML
Publication Date: 2022

Variant appearance in text: PIK3CA: His1047Arg
PubMed Link: 35282432
Variant Present in the following documents:
  • fendo-13-834362.pdf
View BVdb publication page



Multi-institutional Analysis of the Clinical and Genomic Characteristics of Black Patients with Metastatic Hormone-Sensitive Prostate Cancer.

The Oncologist
Freeman, Meredith N MN; Jang, Albert A; Zhu, Jason J; Sanati, Farhad F; Nandagopal, Lakshminarayanan L; Ravindranathan, Deepak D; Desai, Arpita A; Phone, Audrey A; Nussenzveig, Roberto R; Jaeger, Ellen E; Caputo, Sydney A SA; Koshkin, Vadim S VS; Swami, Umang U; Basu, Arnab A; Bilen, Mehmet A MA; Agarwal, Neeraj N; Sartor, Oliver O; Burgess, Earle F EF; Barata, Pedro C PC
Publication Date: 2022-03-11

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35274720
Variant Present in the following documents:
  • oyab057.pdf
View BVdb publication page



The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology
Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q
Publication Date: 2021

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35273907
Variant Present in the following documents:
  • Table_7.xlsx
  • fonc-11-751106.pdf
View BVdb publication page



Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation.

Communications Biology
Goldhammer, Nadine N; Kim, Jiyoung J; Villadsen, René R; Rønnov-Jessen, Lone L; Petersen, Ole William OW
Publication Date: 2022-03-10

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35273332
Variant Present in the following documents:
  • 42003_2022_Article_3161.pdf
  • 42003_2022_3161_MOESM1_ESM.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx
View BVdb publication page



PIK3CA Gene Mutations in HNSCC: Systematic Review and Correlations with HPV Status and Patient Survival.

Cancers
Cochicho, Daniela D; Esteves, Susana S; Rito, Miguel M; Silva, Fernanda F; Martins, Luís L; Montalvão, Pedro P; Cunha, Mário M; Magalhães, Miguel M; Gil da Costa, Rui M RM; Felix, Ana A
Publication Date: 2022-03-02

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35267596
Variant Present in the following documents:
  • cancers-14-01286.pdf
View BVdb publication page



Evaluation of the Clinical Utility of Genomic Profiling to Inform Selection of Clinical Trial Therapy in Salivary Gland Cancer.

Cancers
Rack, Samuel S; Feeney, Laura L; Hapuarachi, Brindley B; Adderley, Helen H; Woodhouse, Laura L; Betts, Guy G; Burghel, George J GJ; Harrington, Kevin J KJ; Metcalf, Robert R
Publication Date: 2022-02-23

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35267442
Variant Present in the following documents:
  • cancers-14-01133.pdf
View BVdb publication page



PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment.

Journal For Immunotherapy Of Cancer
Collins, Natalie B NB; Al Abosy, Rose R; Miller, Brian C BC; Bi, Kevin K; Zhao, Qihong Q; Quigley, Michael M; Ishizuka, Jeffrey J JJ; Yates, Kathleen B KB; Pope, Hans W HW; Manguso, Robert T RT; Shrestha, Yashaswi Y; Wadsworth, Marc M; Hughes, Travis T; Shalek, Alex K AK; Boehm, Jesse S JS; Hahn, William C WC; Doench, John G JG; Haining, W Nicholas WN
Publication Date: 2022-03

Variant appearance in text: PIK3CA: 3140A>G
PubMed Link: 35264433
Variant Present in the following documents:
  • jitc-2021-003402supp001.pdf
  • jitc-2021-003402.pdf
View BVdb publication page



The impact of whole genome and transcriptome analysis (WGTA) on predictive biomarker discovery and diagnostic accuracy of advanced malignancies.

The Journal Of Pathology. Clinical Research
Tessier-Cloutier, Basile B; Grewal, Jasleen K JK; Jones, Martin R MR; Pleasance, Erin E; Shen, Yaoqing Y; Cai, Ellen E; Dunham, Chris C; Hoang, Lynn L; Horst, Basil B; Huntsman, David G DG; Ionescu, Diana D; Karnezis, Anthony N AN; Lee, Anna F AF; Lee, Cheng Han CH; Lee, Tae Hoon TH; Twa, David Dw DD; Mungall, Andrew J AJ; Mungall, Karen K; Naso, Julia R JR; Ng, Tony T; Schaeffer, David F DF; Sheffield, Brandon S BS; Skinnider, Brian B; Smith, Tyler T; Williamson, Laura L; Zhong, Ellia E; Regier, Dean A DA; Laskin, Janessa J; Marra, Marco A MA; Gilks, C Blake CB; Jones, Steven Jm SJ; Yip, Stephen S
Publication Date: 2022-03-08

Variant appearance in text: PIK3CA: 3140A>G; H1047R
PubMed Link: 35257510
Variant Present in the following documents:
  • CJP2-8-395-s002.xlsx
View BVdb publication page



Molecular landscape of osimertinib resistance in patients and patient-derived preclinical models.

Therapeutic Advances In Medical Oncology
Lim, Sun Min SM; Yang, San-Duk SD; Lim, Sangbin S; Heo, Seong Gu SG; Daniel, Stetson S; Markovets, Aleksandra A; Minoo, Rafati R; Pyo, Kyoung-Ho KH; Yun, Mi Ran MR; Hong, Min Hee MH; Kim, Hye Ryun HR; Cho, Byoung Chul BC
Publication Date: 2022

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35251316
Variant Present in the following documents:
  • 10.1177_17588359221079125.pdf
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In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.

Journal For Immunotherapy Of Cancer
Ieranò, Caterina C; Righelli, Dario D; D'Alterio, Crescenzo C; Napolitano, Maria M; Portella, Luigi L; Rea, Giuseppina G; Auletta, Federica F; Santagata, Sara S; Trotta, Anna Maria AM; Guardascione, Giuseppe G; Liotti, Federica F; Prevete, Nella N; Maiolino, Piera P; Luciano, Antonio A; Barbieri, Antonio A; Di Mauro, Annabella A; Roma, Cristin C; Esposito Abate, Riziero R; Tatangelo, Fabiana F; Pacelli, Roberto R; Normanno, Nicola N; Melillo, Rosa Marina RM; Scala, Stefania S
Publication Date: 2022-03

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35246475
Variant Present in the following documents:
  • jitc-2021-004032supp001.pdf
View BVdb publication page



Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis.

Cellular & Molecular Biology Letters
Homayoonfal, Mina M; Asemi, Zatollah Z; Yousefi, Bahman B
Publication Date: 2022-03-02

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35236304
Variant Present in the following documents:
  • 11658_2022_Article_320.pdf
View BVdb publication page



In vitro anticancer effects of alpelisib against PIK3CA‑mutated canine hemangiosarcoma cell lines.

Oncology Reports
Maeda, Marika M; Ochiai, Kazuhiko K; Michishita, Masaki M; Morimatsu, Masami M; Sakai, Hiroki H; Kinoshita, Nayuta N; Sakaue, Motoharu M; Onozawa, Eri E; Azakami, Daigo D; Yamamoto, Masami M; Ishioka, Katsumi K; Sadahira, Takuya T; Watanabe, Masami M; Tanaka, Yoshikazu Y
Publication Date: 2022-04

Variant appearance in text: PIK3CA: H1047R
PubMed Link: 35234262
Variant Present in the following documents:
  • Supplementary_Data2.pdf
View BVdb publication page