SCN5A c.1546_1548delinsGAG ;(p.S516E)

Variant ID: 3-38645545-GCT-CTC

NM_000335.4(SCN5A):c.1546_1548delinsGAG;(p.S516E)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


CaMKII-dependent regulation of cardiac Na(+) homeostasis.

Frontiers In Pharmacology
Grandi, Eleonora E; Herren, Anthony W AW
Publication Date: 2014

Variant appearance in text: SCN5A: S516E
PubMed Link: 24653702
Variant Present in the following documents:
  • Main text
  • fphar-05-00041.pdf
View BVdb publication page



Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias.

American Journal Of Physiology. Heart And Circulatory Physiology
Herren, Anthony W AW; Bers, Donald M DM; Grandi, Eleonora E
Publication Date: 2013-08-15

Variant appearance in text: SCN5A: S516E
PubMed Link: 23771687
Variant Present in the following documents:
  • Main text
View BVdb publication page



Na(+) channel I-II loop mediates parallel genetic and phosphorylation-dependent gating changes.

Circulation
Bers, Donald M DM; Herren, Anthony W AW
Publication Date: 2012-10-23

Variant appearance in text: SCN5A: S516E
PubMed Link: 23091083
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.

The Journal Of Biological Chemistry
Ashpole, Nicole M NM; Herren, Anthony W AW; Ginsburg, Kenneth S KS; Brogan, Joseph D JD; Johnson, Derrick E DE; Cummins, Theodore R TR; Bers, Donald M DM; Hudmon, Andy A
Publication Date: 2012-06-08

Variant appearance in text: Nav1.5: S516E
PubMed Link: 22514276
Variant Present in the following documents:
  • Main text
View BVdb publication page