Monitoring Treatment Response, Early Recurrence, and Survival in Uterine Serous Carcinoma and Carcinosarcoma Patients Using Personalized Circulating Tumor DNA Biomarkers.
International Journal Of Molecular Sciences
Bellone, Stefania S; McNamara, Blair B; Mutlu, Levent L; Demirkiran, Cem C; Hartwich, Tobias Max Philipp TMP; Harold, Justin J; Yang-Hartwich, Yang Y; Siegel, Eric R ER; Santin, Alessandro D AD
Genome-wide analysis toward the epigenetic aetiology of myelodysplastic syndrome disease progression and pharmacoepigenomic basis of hypomethylating agents drug treatment response.
Human Genomics
Siamoglou, Stavroula S; Boers, Ruben R; Koromina, Maria M; Boers, Joachim J; Tsironi, Anna A; Chatzilygeroudi, Theodora T; Lazaris, Vasileios V; Verigou, Evgenia E; Kourakli, Alexandra A; van IJcken, Wilfred F J WFJ; Gribnau, Joost J; Symeonidis, Argiris A; Patrinos, George P GP
Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning.
Nature Communications
de Jong, Anouk C AC; Danyi, Alexandra A; van Riet, Job J; de Wit, Ronald R; Sjöström, Martin M; Feng, Felix F; de Ridder, Jeroen J; Lolkema, Martijn P MP
Publication Date: 2023-04-08
Variant appearance in text: CTNNB1: S45F; rs121913409
The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.
Research Square
Murphy, Andrew J AJ; Cheng, Changde C; Williams, Justin J; Shaw, Timothy I TI; Pinto, Emilia M EM; Dieseldorff-Jones, Karissa K; Brzezinski, Jack J; Renfro, Lindsay A LA; Tornwall, Brett B; Huff, Vicki V; Hong, Andrew L AL; Mullen, Elizabeth A EA; Crompton, Brian B; Dome, Jeffrey S JS; Fernandez, Conrad V CV; Geller, James I JI; Ehrlich, Peter F PF; Mulder, Heather H; Oak, Ninad N; Maciezsek, Jamie J; Jablonowski, Carolyn C; Fleming, Andrew M AM; Pichavaram, Prahalathan P; Morton, Christopher L CL; Easton, John J; Nichols, Kim E KE; Clay, Michael R MR; Santiago, Teresa T; Zhang, Jinghui J; Yang, Jun J; Zambetti, Gerard P GP; Wang, Zhaoming Z; Davidoff, Andrew M AM; Chen, Xiang X
Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09
Variant appearance in text: CTNNB1: 134C>T; Ser45Phe; rs121913409
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: CTNNB1: 134C>T; Ser45Phe
Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Unexplained mismatch repair deficiency: Case closed.
Hgg Advances
Eikenboom, Ellis L EL; Moen, Sarah S; van Leeuwen, Lotte L; Geurts-Giele, Willemina R R WRR; Tops, Carli M J CMJ; van Ham, Tjakko J TJ; Dinjens, Winand N M WNM; Dubbink, Hendrikus J HJ; Spaander, Manon C W MCW; Wagner, Anja A
Therapeutic Implications of TGF-β Pathway in Desmoid Tumor Based on Comprehensive Molecular Profiling and Clinicopathological Properties.
Cancers
Yun, Kum-Hee KH; Park, Changhee C; Ryu, Hyang Joo HJ; Ock, Chan-Young CY; Lee, Young Han YH; Baek, Wooyeol W; Yoon, Hong In HI; Han, Yoon Dae YD; Kim, Sang Kyum SK; Lee, JooHee J; Kim, Seong-Jin SJ; Yang, Kyung-Min KM; Kim, Seung Hyun SH; Kim, Hyo Song HS
Diagnostic accuracy of mutational analysis along the Müllerian tract to detect ovarian cancer.
International Journal Of Gynecological Cancer : Official Journal Of The International Gynecological Cancer Society
van Bommel, Majke H D MHD; Pijnenborg, Johanna M A JMA; van der Putten, Louis J M LJM; Bulten, Johan J; Snijders, Marc P L M MPLM; Küsters-Vandevelde, Heidi V N HVN; Sweegers, Sanne S; Vos, M Caroline MC; Ligtenberg, Marjolein J L MJL; Eijkelenboom, Astrid A; de Hullu, Joanne A JA; Reijnen, Casper C
Publication Date: 2022-11-16
Variant appearance in text: CTNNB1: 134C>T; Ser45Phe
Challenges and opportunities associated with the MD Anderson IMPACT2 randomized study in precision oncology.
Npj Precision Oncology
Vo, Henry Hiep HH; Fu, Siqing S; Hong, David S DS; Karp, Daniel D DD; Piha-Paul, Sarina S; Subbiah, Vivek V; Janku, Filip F; Naing, Aung A; Yap, Timothy A TA; Rodon, Jordi J; Ajani, Jaffer A JA; Cartwright, Carrie C; Johnson, Amber A; Song, I-Wen IW; Beck, Jennifer J; Kahle, Michael M; Nogueras-Gonzalez, Graciela M GM; Miller, Vincent V; Chao, Calvin C; Vining, David J DJ; Berry, Donald A DA; Meric-Bernstam, Funda F; Tsimberidou, Apostolia-Maria AM
bMSAF is a prognostic predictor for advanced hepatocellular carcinoma patients treated with immune checkpoint inhibitor camrelizumab and anti-angiogenic agent apatinib combination therapy.
The mutational landscape of cancer's vulnerability to ionizing radiation.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME
Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.
The Journal Of Pathology
Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ
Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.
Pathobiology : Journal Of Immunopathology, Molecular And Cellular Biology
Haefliger, Simon S; Marston, Katharina K; Alborelli, Ilaria I; Stauffer, Edouard-Jean EJ; Gugger, Mathias M; Jermann, Philip M PM; Hoeller, Sylvia S; Tornillo, Luigi L; Terracciano, Luigi M LM; Bihl, Michel M; Matter, Matthias S MS
Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions.
Cancers
Zaremba, Anne A; Jansen, Philipp P; Murali, Rajmohan R; Mayakonda, Anand A; Riedel, Anna A; Krahl, Dieter D; Burkhardt, Hans H; John, Stefan S; Géraud, Cyrill C; Philip, Manuel M; Kretz, Julia J; Möller, Inga I; Stadtler, Nadine N; Sucker, Antje A; Paschen, Annette A; Ugurel, Selma S; Zimmer, Lisa L; Livingstone, Elisabeth E; Horn, Susanne S; Plass, Christoph C; Schadendorf, Dirk D; Hadaschik, Eva E; Lutsik, Pavlo P; Griewank, Klaus K
Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Nature Communications
Lenos, Kristiaan J KJ; Bach, Sander S; Ferreira Moreno, Leandro L; Ten Hoorn, Sanne S; Sluiter, Nina R NR; Bootsma, Sanne S; Vieira Braga, Felipe A FA; Nijman, Lisanne E LE; van den Bosch, Tom T; Miedema, Daniel M DM; van Dijk, Erik E; Ylstra, Bauke B; Kulicke, Ruth R; Davis, Fred P FP; Stransky, Nicolas N; Smolen, Gromoslaw A GA; Coebergh van den Braak, Robert R J RRJ; IJzermans, Jan N M JNM; Martens, John W M JWM; Hallam, Sally S; Beggs, Andrew D AD; Kops, Geert J P L GJPL; Lansu, Nico N; Bastiaenen, Vivian P VP; Klaver, Charlotte E L CEL; Lecca, Maria C MC; El Makrini, Khalid K; Elbers, Clara C CC; Dings, Mark P G MPG; van Noesel, Carel J M CJM; Kranenburg, Onno O; Medema, Jan Paul JP; Koster, Jan J; Koens, Lianne L; Punt, Cornelis J A CJA; Tanis, Pieter J PJ; de Hingh, Ignace H IH; Bijlsma, Maarten F MF; Tuynman, Jurriaan B JB; Vermeulen, Louis L
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Somatic targeted mutation profiling of colorectal cancer precursor lesions.
Bmc Medical Genomics
Dos Santos, Wellington W; Dos Reis, Mariana Bisarro MB; Porto, Jun J; de Carvalho, Ana Carolina AC; Matsushita, Marcus M; Oliveira, Gabriela G; Syrjänen, Kari K; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP
Publication Date: 2022-06-28
Variant appearance in text: CTNNB1: S45F; rs121913409
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.
Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes.
Genome Medicine
Goel, Anshita A; Ward, Douglas G DG; Noyvert, Boris B; Yu, Minghao M; Gordon, Naheema S NS; Abbotts, Ben B; Colbourne, John K JK; Kissane, Stephen S; James, Nicholas D ND; Zeegers, Maurice P MP; Cheng, Kar Keung KK; Cazier, Jean-Baptiste JB; Whalley, Celina M CM; Beggs, Andrew D AD; Palles, Claire C; Arnold, Roland R; Bryan, Richard T RT
Publication Date: 2022-06-03
Variant appearance in text: CTNNB1: 134C>T; Ser45Phe; rs121913409
Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.