Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Publication Date: 2022-10-21
Variant appearance in text: ULK4: 1042A>G; Ser348Gly; rs35263917
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.
Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
Publication Date: 2022-06-29
Variant appearance in text: ULK4: S348G; rs35263917
Genomic insights in ascending aortic size and distensibility.
Ebiomedicine
Benjamins, Jan Walter JW; Yeung, Ming Wai MW; van de Vegte, Yordi J YJ; Said, M Abdullah MA; van der Linden, Thijs T; Ties, Daan D; Juarez-Orozco, Luis E LE; Verweij, Niek N; van der Harst, Pim P
Publication Date: 2022-01
Variant appearance in text: ULK4: S348G; rs35263917
Genomic insights in ascending aortic size and distensibility.
Ebiomedicine
Benjamins, Jan Walter JW; Yeung, Ming Wai MW; van de Vegte, Yordi J YJ; Said, M Abdullah MA; van der Linden, Thijs T; Ties, Daan D; Juarez-Orozco, Luis E LE; Verweij, Niek N; van der Harst, Pim P
Publication Date: 2021-12-27
Variant appearance in text: ULK4: S348G; rs35263917
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: ULK4: S348G; rs35263917
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: ULK4: S348G; rs35263917
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Publication Date: 2019-03-20
Variant appearance in text: ULK4: S348G; rs35263917
X-linked ADGRG2 mutation and obstructive azoospermia in a large Pakistani family.
Scientific Reports
Khan, Muhammad Jaseem MJ; Pollock, Nijole N; Jiang, Huaiyang H; Castro, Carlos C; Nazli, Rubina R; Ahmed, Jawad J; Basit, Sulman S; Rajkovic, Aleksandar A; Yatsenko, Alexander N AN
Publication Date: 2018-11-02
Variant appearance in text: ULK4: S348G; rs35263917
A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5.
Blood Cancer Journal
White, Brian S BS; Lanc, Irena I; O'Neal, Julie J; Gupta, Harshath H; Fulton, Robert S RS; Schmidt, Heather H; Fronick, Catrina C; Belter, Edward A EA; Fiala, Mark M; King, Justin J; Ahmann, Greg J GJ; DeRome, Mary M; Mardis, Elaine R ER; Vij, Ravi R; DiPersio, John F JF; Levy, Joan J; Auclair, Daniel D; Tomasson, Michael H MH
A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Rand, Kristin A KA; Song, Chi C; Dean, Eric E; Serie, Daniel J DJ; Curtin, Karen K; Sheng, Xin X; Hu, Donglei D; Huff, Carol Ann CA; Bernal-Mizrachi, Leon L; Tomasson, Michael H MH; Ailawadhi, Sikander S; Singhal, Seema S; Pawlish, Karen K; Peters, Edward S ES; Bock, Cathryn H CH; Stram, Alex A; Van Den Berg, David J DJ; Edlund, Christopher K CK; Conti, David V DV; Zimmerman, Todd T; Hwang, Amie E AE; Huntsman, Scott S; Graff, John J; Nooka, Ajay A; Kong, Yinfei Y; Pregja, Silvana L SL; Berndt, Sonja I SI; Blot, William J WJ; Carpten, John J; Casey, Graham G; Chu, Lisa L; Diver, W Ryan WR; Stevens, Victoria L VL; Lieber, Michael R MR; Goodman, Phyllis J PJ; Hennis, Anselm J M AJ; Hsing, Ann W AW; Mehta, Jayesh J; Kittles, Rick A RA; Kolb, Suzanne S; Klein, Eric A EA; Leske, Cristina C; Murphy, Adam B AB; Nemesure, Barbara B; Neslund-Dudas, Christine C; Strom, Sara S SS; Vij, Ravi R; Rybicki, Benjamin A BA; Stanford, Janet L JL; Signorello, Lisa B LB; Witte, John S JS; Ambrosone, Christine B CB; Bhatti, Parveen P; John, Esther M EM; Bernstein, Leslie L; Zheng, Wei W; Olshan, Andrew F AF; Hu, Jennifer J JJ; Ziegler, Regina G RG; Nyante, Sarah J SJ; Bandera, Elisa V EV; Birmann, Brenda M BM; Ingles, Sue A SA; Press, Michael F MF; Atanackovic, Djordje D; Glenn, Martha J MJ; Cannon-Albright, Lisa A LA; Jones, Brandt B; Tricot, Guido G; Martin, Thomas G TG; Kumar, Shaji K SK; Wolf, Jeffrey L JL; Deming Halverson, Sandra L SL; Rothman, Nathaniel N; Brooks-Wilson, Angela R AR; Rajkumar, S Vincent SV; Kolonel, Laurence N LN; Chanock, Stephen J SJ; Slager, Susan L SL; Severson, Richard K RK; Janakiraman, Nalini N; Terebelo, Howard R HR; Brown, Elizabeth E EE; De Roos, Anneclaire J AJ; Mohrbacher, Ann F AF; Colditz, Graham A GA; Giles, Graham G GG; Spinelli, John J JJ; Chiu, Brian C BC; Munshi, Nikhil C NC; Anderson, Kenneth C KC; Levy, Joan J; Zonder, Jeffrey A JA; Orlowski, Robert Z RZ; Lonial, Sagar S; Camp, Nicola J NJ; Vachon, Celine M CM; Ziv, Elad E; Stram, Daniel O DO; Hazelett, Dennis J DJ; Haiman, Christopher A CA; Cozen, Wendy W
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal Of Pathology
Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R
Publication Date: 2016-11
Variant appearance in text: ULK4: S348G; rs35263917
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: ULK4: S348G; rs35263917
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: ULK4: S348G; rs35263917
NCI-60 whole exome sequencing and pharmacological CellMiner analyses.
Plos One
Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y
Publication Date: 2014
Variant appearance in text: ULK4: S348G; rs35263917
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Nature
, ; Ehret, Georg B GB; Munroe, Patricia B PB; Rice, Kenneth M KM; Bochud, Murielle M; Johnson, Andrew D AD; Chasman, Daniel I DI; Smith, Albert V AV; Tobin, Martin D MD; Verwoert, Germaine C GC; Hwang, Shih-Jen SJ; Pihur, Vasyl V; Vollenweider, Peter P; O'Reilly, Paul F PF; Amin, Najaf N; Bragg-Gresham, Jennifer L JL; Teumer, Alexander A; Glazer, Nicole L NL; Launer, Lenore L; Zhao, Jing Hua JH; Aulchenko, Yurii Y; Heath, Simon S; Sõber, Siim S; Parsa, Afshin A; Luan, Jian'an J; Arora, Pankaj P; Dehghan, Abbas A; Zhang, Feng F; Lucas, Gavin G; Hicks, Andrew A AA; Jackson, Anne U AU; Peden, John F JF; Tanaka, Toshiko T; Wild, Sarah H SH; Rudan, Igor I; Igl, Wilmar W; Milaneschi, Yuri Y; Parker, Alex N AN; Fava, Cristiano C; Chambers, John C JC; Fox, Ervin R ER; Kumari, Meena M; Go, Min Jin MJ; van der Harst, Pim P; Kao, Wen Hong Linda WH; Sjögren, Marketa M; Vinay, D G DG; Alexander, Myriam M; Tabara, Yasuharu Y; Shaw-Hawkins, Sue S; Whincup, Peter H PH; Liu, Yongmei Y; Shi, Gang G; Kuusisto, Johanna J; Tayo, Bamidele B; Seielstad, Mark M; Sim, Xueling X; Nguyen, Khanh-Dung Hoang KD; Lehtimäki, Terho T; Matullo, Giuseppe G; Wu, Ying Y; Gaunt, Tom R TR; Onland-Moret, N Charlotte NC; Cooper, Matthew N MN; Platou, Carl G P CG; Org, Elin E; Hardy, Rebecca R; Dahgam, Santosh S; Palmen, Jutta J; Vitart, Veronique V; Braund, Peter S PS; Kuznetsova, Tatiana T; Uiterwaal, Cuno S P M CS; Adeyemo, Adebowale A; Palmas, Walter W; Campbell, Harry H; Ludwig, Barbara B; Tomaszewski, Maciej M; Tzoulaki, Ioanna I; Palmer, Nicholette D ND; , ; , ; , ; , ; , ; Aspelund, Thor T; Garcia, Melissa M; Chang, Yen-Pei C YP; O'Connell, Jeffrey R JR; Steinle, Nanette I NI; Grobbee, Diederick E DE; Arking, Dan E DE; Kardia, Sharon L SL; Morrison, Alanna C AC; Hernandez, Dena D; Najjar, Samer S; McArdle, Wendy L WL; Hadley, David D; Brown, Morris J MJ; Connell, John M JM; Hingorani, Aroon D AD; Day, Ian N M IN; Lawlor, Debbie A DA; Beilby, John P JP; Lawrence, Robert W RW; Clarke, Robert R; Hopewell, Jemma C JC; Ongen, Halit H; Dreisbach, Albert W AW; Li, Yali Y; Young, J Hunter JH; Bis, Joshua C JC; Kähönen, Mika M; Viikari, Jorma J; Adair, Linda S LS; Lee, Nanette R NR; Chen, Ming-Huei MH; Olden, Matthias M; Pattaro, Cristian C; Bolton, Judith A Hoffman JA; Köttgen, Anna A; Bergmann, Sven S; Mooser, Vincent V; Chaturvedi, Nish N; Frayling, Timothy M TM; Islam, Muhammad M; Jafar, Tazeen H TH; Erdmann, Jeanette J; Kulkarni, Smita R SR; Bornstein, Stefan R SR; Grässler, Jürgen J; Groop, Leif L; Voight, Benjamin F BF; Kettunen, Johannes J; Howard, Philip P; Taylor, Andrew A; Guarrera, Simonetta S; Ricceri, Fulvio F; Emilsson, Valur V; Plump, Andrew A; Barroso, Inês I; Khaw, Kay-Tee KT; Weder, Alan B AB; Hunt, Steven C SC; Sun, Yan V YV; Bergman, Richard N RN; Collins, Francis S FS; Bonnycastle, Lori L LL; Scott, Laura J LJ; Stringham, Heather M HM; Peltonen, Leena L; Perola, Markus M; Vartiainen, Erkki E; Brand, Stefan-Martin SM; Staessen, Jan A JA; Wang, Thomas J TJ; Burton, Paul R PR; Soler Artigas, Maria M; Dong, Yanbin Y; Snieder, Harold H; Wang, Xiaoling X; Zhu, Haidong H; Lohman, Kurt K KK; Rudock, Megan E ME; Heckbert, Susan R SR; Smith, Nicholas L NL; Wiggins, Kerri L KL; Doumatey, Ayo A; Shriner, Daniel D; Veldre, Gudrun G; Viigimaa, Margus M; Kinra, Sanjay S; Prabhakaran, Dorairaj D; Tripathy, Vikal V; Langefeld, Carl D CD; Rosengren, Annika A; Thelle, Dag S DS; Corsi, Anna Maria AM; Singleton, Andrew A; Forrester, Terrence T; Hilton, Gina G; McKenzie, Colin A CA; Salako, Tunde T; Iwai, Naoharu N; Kita, Yoshikuni Y; Ogihara, Toshio T; Ohkubo, Takayoshi T; Okamura, Tomonori T; Ueshima, Hirotsugu H; Umemura, Satoshi S; Eyheramendy, Susana S; Meitinger, Thomas T; Wichmann, H-Erich HE; Cho, Yoon Shin YS; Kim, Hyung-Lae HL; Lee, Jong-Young JY; Scott, James J; Sehmi, Joban S JS; Zhang, Weihua W; Hedblad, Bo B; Nilsson, Peter P; Smith, George Davey GD; Wong, Andrew A; Narisu, Narisu N; Stančáková, Alena A; Raffel, Leslie J LJ; Yao, Jie J; Kathiresan, Sekar S; O'Donnell, Christopher J CJ; Schwartz, Stephen M SM; Ikram, M Arfan MA; Longstreth, W T WT; Mosley, Thomas H TH; Seshadri, Sudha S; Shrine, Nick R G NR; Wain, Louise V LV; Morken, Mario A MA; Swift, Amy J AJ; Laitinen, Jaana J; Prokopenko, Inga I; Zitting, Paavo P; Cooper, Jackie A JA; Humphries, Steve E SE; Danesh, John J; Rasheed, Asif A; Goel, Anuj A; Hamsten, Anders A; Watkins, Hugh H; Bakker, Stephan J L SJ; van Gilst, Wiek H WH; Janipalli, Charles S CS; Mani, K Radha KR; Yajnik, Chittaranjan S CS; Hofman, Albert A; Mattace-Raso, Francesco U S FU; Oostra, Ben A BA; Demirkan, Ayse A; Isaacs, Aaron A; Rivadeneira, Fernando F; Lakatta, Edward G EG; Orru, Marco M; Scuteri, Angelo A; Ala-Korpela, Mika M; Kangas, Antti J AJ; Lyytikäinen, Leo-Pekka LP; Soininen, Pasi P; Tukiainen, Taru T; Würtz, Peter P; Ong, Rick Twee-Hee RT; Dörr, Marcus M; Kroemer, Heyo K HK; Völker, Uwe U; Völzke, Henry H; Galan, Pilar P; Hercberg, Serge S; Lathrop, Mark M; Zelenika, Diana D; Deloukas, Panos P; Mangino, Massimo M; Spector, Tim D TD; Zhai, Guangju G; Meschia, James F JF; Nalls, Michael A MA; Sharma, Pankaj P; Terzic, Janos J; Kumar, M V Kranthi MV; Denniff, Matthew M; Zukowska-Szczechowska, Ewa E; Wagenknecht, Lynne E LE; Fowkes, F Gerald R FG; Charchar, Fadi J FJ; Schwarz, Peter E H PE; Hayward, Caroline C; Guo, Xiuqing X; Rotimi, Charles C; Bots, Michiel L ML; Brand, Eva E; Samani, Nilesh J NJ; Polasek, Ozren O; Talmud, Philippa J PJ; Nyberg, Fredrik F; Kuh, Diana D; Laan, Maris M; Hveem, Kristian K; Palmer, Lyle J LJ; van der Schouw, Yvonne T YT; Casas, Juan P JP; Mohlke, Karen L KL; Vineis, Paolo P; Raitakari, Olli O; Ganesh, Santhi K SK; Wong, Tien Y TY; Tai, E Shyong ES; Cooper, Richard S RS; Laakso, Markku M; Rao, Dabeeru C DC; Harris, Tamara B TB; Morris, Richard W RW; Dominiczak, Anna F AF; Kivimaki, Mika M; Marmot, Michael G MG; Miki, Tetsuro T; Saleheen, Danish D; Chandak, Giriraj R GR; Coresh, Josef J; Navis, Gerjan G; Salomaa, Veikko V; Han, Bok-Ghee BG; Zhu, Xiaofeng X; Kooner, Jaspal S JS; Melander, Olle O; Ridker, Paul M PM; Bandinelli, Stefania S; Gyllensten, Ulf B UB; Wright, Alan F AF; Wilson, James F JF; Ferrucci, Luigi L; Farrall, Martin M; Tuomilehto, Jaakko J; Pramstaller, Peter P PP; Elosua, Roberto R; Soranzo, Nicole N; Sijbrands, Eric J G EJ; Altshuler, David D; Loos, Ruth J F RJ; Shuldiner, Alan R AR; Gieger, Christian C; Meneton, Pierre P; Uitterlinden, Andre G AG; Wareham, Nicholas J NJ; Gudnason, Vilmundur V; Rotter, Jerome I JI; Rettig, Rainer R; Uda, Manuela M; Strachan, David P DP; Witteman, Jacqueline C M JC; Hartikainen, Anna-Liisa AL; Beckmann, Jacques S JS; Boerwinkle, Eric E; Vasan, Ramachandran S RS; Boehnke, Michael M; Larson, Martin G MG; Järvelin, Marjo-Riitta MR; Psaty, Bruce M BM; Abecasis, Gonçalo R GR; Chakravarti, Aravinda A; Elliott, Paul P; van Duijn, Cornelia M CM; Newton-Cheh, Christopher C; Levy, Daniel D; Caulfield, Mark J MJ; Johnson, Toby T
Publication Date: 2011-09-11
Variant appearance in text: ULK4: S348G; rs35263917