TET2 c.295_296delinsGC ;(p.S99A)

Variant ID: 4-106155394-AG-GC

NM_001127208.2(TET2):c.295_296delinsGC;(p.S99A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation.

The Journal Of Biological Chemistry
Kundu, Anirban A; Shelar, Sandeep S; Ghosh, Arindam P AP; Ballestas, Mary M; Kirkman, Richard R; Nam, Hyeyoung H; Brinkley, Garrett J GJ; Karki, Suman S; Mobley, James A JA; Bae, Sejong S; Varambally, Sooryanarayana S; Sudarshan, Sunil S
Publication Date: 2020-02-07

Variant appearance in text: TET2: S99A
PubMed Link: 31901078
Variant Present in the following documents:
  • Main text
View BVdb publication page



TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer.

Cell Research
Chen, Hao H; Yu, Dingdang D; Fang, Rui R; Rabidou, Kimberlie K; Wu, Di D; Hu, Di D; Jia, Peilin P; Zhao, Zhongming Z; Wu, Zhiping Z; Peng, Junmin J; Shi, Yang Y; Shi, Yujiang Geno YG
Publication Date: 2019-03

Variant appearance in text: TET2: S99A
PubMed Link: 30607016
Variant Present in the following documents:
  • Main text
View BVdb publication page



Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.

Nature
Wu, Di D; Hu, Di D; Chen, Hao H; Shi, Guoming G; Fetahu, Irfete S IS; Wu, Feizhen F; Rabidou, Kimberlie K; Fang, Rui R; Tan, Li L; Xu, Shuyun S; Liu, Hang H; Argueta, Christian C; Zhang, Lei L; Mao, Fei F; Yan, Guoquan G; Chen, Jiajia J; Dong, Zhaoru Z; Lv, Ruitu R; Xu, Yufei Y; Wang, Mei M; Ye, Yong Y; Zhang, Shike S; Duquette, Danielle D; Geng, Songmei S; Yin, Clark C; Lian, Christine Guo CG; Murphy, George F GF; Adler, Gail K GK; Garg, Rajesh R; Lynch, Lydia L; Yang, Pengyuan P; Li, Yiming Y; Lan, Fei F; Fan, Jia J; Shi, Yang Y; Shi, Yujiang Geno YG
Publication Date: 2018-07

Variant appearance in text: TET2: S99A
PubMed Link: 30022161
Variant Present in the following documents:
  • Main text
View BVdb publication page