Publications:

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: TET2: 1771C>T; Q591*

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia

Jahn, Nikolaus N; Jahn, Ekaterina E; Saadati, Maral M; Bullinger, Lars L; Larson, Richard A RA; Ottone, Tiziana T; Amadori, Sergio S; Prior, Thomas W TW; Brandwein, Joseph M JM; Appelbaum, Frederick R FR; Medeiros, Bruno C BC; Tallman, Martin S MS; Ehninger, Gerhard G; Heuser, Michael M; Ganser, Arnold A; Pallaud, Celine C; Gathmann, Insa I; Krzykalla, Julia J; Benner, Axel A; Bloomfield, Clara D CD; Thiede, Christian C; Stone, Richard M RM; Döhner, Hartmut H; Döhner, Konstanze K

Publication Date: 2022-09

Variant appearance in text: TET2: Q591X

PubMed Link: 35922444

Variant Present in the following documents:

• 41375_2022_1650_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic and immunohistochemical profiling of NK/T-cell Lymphomas reveals prognostically relevant BCOR-MYC association.

Blood Advances

Oishi, Naoki N; Satou, Akira A; Miyaoka, Masashi M; Kawashima, Ichiro I; Segawa, Takahiro T; Miyake, Kunio K; Mochizuki, Kunio K; Kirito, Keita K; Feldman, Andrew A; Nakamura, Naoya N; Kondo, Tetsuo T

Publication Date: 2022-07-26

Variant appearance in text: TET2: 1771C>T; Q591X

PubMed Link: 35882439

Variant Present in the following documents:

• BLOODA_ADV-2022-007541-mmc2.xlsx, sheet 1

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: TET2: Q591*

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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The longitudinal dynamics and natural history of clonal haematopoiesis.

Nature

Fabre, Margarete A MA; de Almeida, José Guilherme JG; Fiorillo, Edoardo E; Mitchell, Emily E; Damaskou, Aristi A; Rak, Justyna J; Orrù, Valeria V; Marongiu, Michele M; Chapman, Michael Spencer MS; Vijayabaskar, M S MS; Baxter, Joanna J; Hardy, Claire C; Abascal, Federico F; Williams, Nicholas N; Nangalia, Jyoti J; Martincorena, Iñigo I; Campbell, Peter J PJ; McKinney, Eoin F EF; Cucca, Francesco F; Gerstung, Moritz M; Vassiliou, George S GS

Publication Date: 2022-06

Variant appearance in text: TET2: Q591X

PubMed Link: 35650444

Variant Present in the following documents:

• 41586_2022_4785_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models.

Elife

Chalabi Hajkarim, Morteza M; Karjalainen, Ella E; Osipovitch, Mikhail M; Dimopoulos, Konstantinos K; Gordon, Sandra L SL; Ambri, Francesca F; Rasmussen, Kasper Dindler KD; Grønbæk, Kirsten K; Helin, Kristian K; Wennerberg, Krister K; Won, Kyoung-Jae KJ

Publication Date: 2022-02-15

Variant appearance in text: TET2: 1771C>T; Gln591*

PubMed Link: 35166670

Variant Present in the following documents:

• elife-73760-supp3.xlsx, sheet 1

View BVdb publication page

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Association of clonal hematopoiesis with chronic obstructive pulmonary disease.

Blood

Miller, Peter G PG; Qiao, Dandi D; Rojas-Quintero, Joselyn J; Honigberg, Michael C MC; Sperling, Adam S AS; Gibson, Christopher J CJ; Bick, Alexander G AG; Niroula, Abhishek A; McConkey, Marie E ME; Sandoval, Brittany B; Miller, Brian C BC; Shi, Weiwei W; Viswanathan, Kaushik K; Leventhal, Matthew M; Werner, Lillian L; Moll, Matthew M; Cade, Brian E BE; Barr, R Graham RG; Correa, Adolfo A; Cupples, L Adrienne LA; Gharib, Sina A SA; Jain, Deepti D; Gogarten, Stephanie M SM; Lange, Leslie A LA; London, Stephanie J SJ; Manichaikul, Ani A; O'Connor, George T GT; Oelsner, Elizabeth C EC; Redline, Susan S; Rich, Stephen S SS; Rotter, Jerome I JI; Ramachandran, Vasan V; Yu, Bing B; Sholl, Lynette L; Neuberg, Donna D; Jaiswal, Siddhartha S; Levy, Bruce D BD; Owen, Caroline A CA; Natarajan, Pradeep P; Silverman, Edwin K EK; van Galen, Peter P; Tesfaigzi, Yohannes Y; Cho, Michael H MH; Ebert, Benjamin L BL; ,

Publication Date: 2022-01-20

Variant appearance in text: TET2: Q591X

PubMed Link: 34855941

Variant Present in the following documents:

• 10.1182-2021013531_bloodbld2021013531-suppl1.pdf
• bloodBLD2021013531-suppl1.pdf

View BVdb publication page

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Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Fangazio, Marco M; Ladewig, Erik E; Gomez, Karen K; Garcia-Ibanez, Laura L; Kumar, Rahul R; Teruya-Feldstein, Julie J; Rossi, Davide D; Filip, Ioan I; Pan-Hammarström, Qiang Q; Inghirami, Giorgio G; Boldorini, Renzo R; Ott, German G; Staiger, Annette M AM; Chapuy, Björn B; Gaidano, Gianluca G; Bhagat, Govind G; Basso, Katia K; Rabadan, Raul R; Pasqualucci, Laura L; Dalla-Favera, Riccardo R

Publication Date: 2021-06-01

Variant appearance in text: TET2: Q591*

PubMed Link: 34050029

Variant Present in the following documents:

• pnas.2104504118.sd02.xlsx, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TET2: 1771C>T; Q591*

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Clinical And Translational Medicine

Li, Ziyang Z; Huang, Wensou W; Yin, Jiani C JC; Na, Chenglong C; Wu, Xue X; Shao, Yang Y; Ding, Huaxin H; Li, Jinming J

Publication Date: 2020-11

Variant appearance in text: TET2: 1771C>T; Q591X

PubMed Link: 33252848

Variant Present in the following documents:

• CTM2-10-e222-s003.xlsx, sheet 1

View BVdb publication page

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Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.

Hemasphere

Fontana, Diletta D; Ramazzotti, Daniele D; Aroldi, Andrea A; Redaelli, Sara S; Magistroni, Vera V; Pirola, Alessandra A; Niro, Antonio A; Massimino, Luca L; Mastini, Cristina C; Brambilla, Virginia V; Bombelli, Silvia S; Bungaro, Silvia S; Morotti, Alessandro A; Rea, Delphine D; Stagno, Fabio F; Martino, Bruno B; Campiotti, Leonardo L; Caocci, Giovanni G; Usala, Emilio E; Merli, Michele M; Onida, Francesco F; Bregni, Marco M; Elli, Elena Maria EM; Fumagalli, Monica M; Ciceri, Fabio F; Perego, Roberto A RA; Pagni, Fabio F; Mologni, Luca L; Piazza, Rocco R; Gambacorti-Passerini, Carlo C

Publication Date: 2020-12

Variant appearance in text: TET2: 1771C>T; Gln591Ter

PubMed Link: 33196013

Variant Present in the following documents:

• hs9-4-e497-s004.xlsx, sheet 1

View BVdb publication page

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Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Nature

Bick, Alexander G AG; Weinstock, Joshua S JS; Nandakumar, Satish K SK; Fulco, Charles P CP; Bao, Erik L EL; Zekavat, Seyedeh M SM; Szeto, Mindy D MD; Liao, Xiaotian X; Leventhal, Matthew J MJ; Nasser, Joseph J; Chang, Kyle K; Laurie, Cecelia C; Burugula, Bala Bharathi BB; Gibson, Christopher J CJ; Lin, Amy E AE; Taub, Margaret A MA; Aguet, Francois F; Ardlie, Kristin K; Mitchell, Braxton D BD; Barnes, Kathleen C KC; Moscati, Arden A; Fornage, Myriam M; Redline, Susan S; Psaty, Bruce M BM; Silverman, Edwin K EK; Weiss, Scott T ST; Palmer, Nicholette D ND; Vasan, Ramachandran S RS; Burchard, Esteban G EG; Kardia, Sharon L R SLR; He, Jiang J; Kaplan, Robert C RC; Smith, Nicholas L NL; Arnett, Donna K DK; Schwartz, David A DA; Correa, Adolfo A; de Andrade, Mariza M; Guo, Xiuqing X; Konkle, Barbara A BA; Custer, Brian B; Peralta, Juan M JM; Gui, Hongsheng H; Meyers, Deborah A DA; McGarvey, Stephen T ST; Chen, Ida Yii-Der IY; Shoemaker, M Benjamin MB; Peyser, Patricia A PA; Broome, Jai G JG; Gogarten, Stephanie M SM; Wang, Fei Fei FF; Wong, Quenna Q; Montasser, May E ME; Daya, Michelle M; Kenny, Eimear E EE; North, Kari E KE; Launer, Lenore J LJ; Cade, Brian E BE; Bis, Joshua C JC; Cho, Michael H MH; Lasky-Su, Jessica J; Bowden, Donald W DW; Cupples, L Adrienne LA; Mak, Angel C Y ACY; Becker, Lewis C LC; Smith, Jennifer A JA; Kelly, Tanika N TN; Aslibekyan, Stella S; Heckbert, Susan R SR; Tiwari, Hemant K HK; Yang, Ivana V IV; Heit, John A JA; Lubitz, Steven A SA; Johnsen, Jill M JM; Curran, Joanne E JE; Wenzel, Sally E SE; Weeks, Daniel E DE; Rao, Dabeeru C DC; Darbar, Dawood D; Moon, Jee-Young JY; Tracy, Russell P RP; Buth, Erin J EJ; Rafaels, Nicholas N; Loos, Ruth J F RJF; Durda, Peter P; Liu, Yongmei Y; Hou, Lifang L; Lee, Jiwon J; Kachroo, Priyadarshini P; Freedman, Barry I BI; Levy, Daniel D; Bielak, Lawrence F LF; Hixson, James E JE; Floyd, James S JS; Whitsel, Eric A EA; Ellinor, Patrick T PT; Irvin, Marguerite R MR; Fingerlin, Tasha E TE; Raffield, Laura M LM; Armasu, Sebastian M SM; Wheeler, Marsha M MM; Sabino, Ester C EC; Blangero, John J; Williams, L Keoki LK; Levy, Bruce D BD; Sheu, Wayne Huey-Herng WH; Roden, Dan M DM; Boerwinkle, Eric E; Manson, JoAnn E JE; Mathias, Rasika A RA; Desai, Pinkal P; Taylor, Kent D KD; Johnson, Andrew D AD; , ; Auer, Paul L PL; Kooperberg, Charles C; Laurie, Cathy C CC; Blackwell, Thomas W TW; Smith, Albert V AV; Zhao, Hongyu H; Lange, Ethan E; Lange, Leslie L; Rich, Stephen S SS; Rotter, Jerome I JI; Wilson, James G JG; Scheet, Paul P; Kitzman, Jacob O JO; Lander, Eric S ES; Engreitz, Jesse M JM; Ebert, Benjamin L BL; Reiner, Alexander P AP; Jaiswal, Siddhartha S; Abecasis, Gonçalo G; Sankaran, Vijay G VG; Kathiresan, Sekar S; Natarajan, Pradeep P

Publication Date: 2020-10

Variant appearance in text: TET2: Q591X

PubMed Link: 33057201

Variant Present in the following documents:

• NIHMS1609346-supplement-1609346_SuppTables.xlsx, sheet 4

View BVdb publication page

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The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.

Nature Communications

Pinese, Mark M; Lacaze, Paul P; Rath, Emma M EM; Stone, Andrew A; Brion, Marie-Jo MJ; Ameur, Adam A; Nagpal, Sini S; Puttick, Clare C; Husson, Shane S; Degrave, Dmitry D; Cristina, Tina Navin TN; Kahl, Vivian F S VFS; Statham, Aaron L AL; Woods, Robyn L RL; McNeil, John J JJ; Riaz, Moeen M; Barr, Margo M; Nelson, Mark R MR; Reid, Christopher M CM; Murray, Anne M AM; Shah, Raj C RC; Wolfe, Rory R; Atkins, Joshua R JR; Fitzsimmons, Chantel C; Cairns, Heath M HM; Green, Melissa J MJ; Carr, Vaughan J VJ; Cowley, Mark J MJ; Pickett, Hilda A HA; James, Paul A PA; Powell, Joseph E JE; Kaplan, Warren W; Gibson, Greg G; Gyllensten, Ulf U; Cairns, Murray J MJ; McNamara, Martin M; Dinger, Marcel E ME; Thomas, David M DM

Publication Date: 2020-01-23

Variant appearance in text: TET2: Gln591Ter

PubMed Link: 31974348

Variant Present in the following documents:

• 41467_2019_14079_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes.

Nature Communications

Nagata, Yasunobu Y; Makishima, Hideki H; Kerr, Cassandra M CM; Przychodzen, Bartlomiej P BP; Aly, Mai M; Goyal, Abhinav A; Awada, Hassan H; Asad, Mohammad Fahad MF; Kuzmanovic, Teodora T; Suzuki, Hiromichi H; Yoshizato, Tetsuichi T; Yoshida, Kenichi K; Chiba, Kenichi K; Tanaka, Hiroko H; Shiraishi, Yuichi Y; Miyano, Satoru S; Mukherjee, Sudipto S; LaFramboise, Thomas T; Nazha, Aziz A; Sekeres, Mikkael A MA; Radivoyevitch, Tomas T; Haferlach, Torsten T; Ogawa, Seishi S; Maciejewski, Jaroslaw P JP

Publication Date: 2019-11-26

Variant appearance in text: TET2: Q591X

PubMed Link: 31772163

Variant Present in the following documents:

• 41467_2019_13001_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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The modular network structure of the mutational landscape of Acute Myeloid Leukemia.

Plos One

Ibáñez, Mariam M; Carbonell-Caballero, José J; Such, Esperanza E; García-Alonso, Luz L; Liquori, Alessandro A; López-Pavía, María M; Llop, Marta M; Alonso, Carmen C; Barragán, Eva E; Gómez-Seguí, Inés I; Neef, Alexander A; Hervás, David D; Montesinos, Pau P; Sanz, Guillermo G; Sanz, Miguel Angel MA; Dopazo, Joaquín J; Cervera, José J

Publication Date: 2018

Variant appearance in text: TET2: Gln591Ter

PubMed Link: 30303964

Variant Present in the following documents:

• pone.0202926.s006.pdf

View BVdb publication page

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Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.

Nature Communications

Wong, Terrence N TN; Miller, Christopher A CA; Jotte, Matthew R M MRM; Bagegni, Nusayba N; Baty, Jack D JD; Schmidt, Amy P AP; Cashen, Amanda F AF; Duncavage, Eric J EJ; Helton, Nichole M NM; Fiala, Mark M; Fulton, Robert S RS; Heath, Sharon E SE; Janke, Megan M; Luber, Kierstin K; Westervelt, Peter P; Vij, Ravi R; DiPersio, John F JF; Welch, John S JS; Graubert, Timothy A TA; Walter, Matthew J MJ; Ley, Timothy J TJ; Link, Daniel C DC

Publication Date: 2018-01-31

Variant appearance in text: TET2: Q591*

PubMed Link: 29386642

Variant Present in the following documents:

• 41467_2018_2858_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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Prognostic impact of gene mutations in myelodysplastic syndromes with ring sideroblasts.

Blood Cancer Journal

Martín, Iván I; Such, Esperanza E; Navarro, Blanca B; Villamón, Eva E; Vicente, Ana A; Mora, Elvira E; Pedrola, Laia L; Ibáñez, Mariam M; López-Pavía, María M; Tormo, Mar M; Serrano, Alicia A; Sanz, Miguel Ángel MÁ; Cervera, José J; Sanz, Guillermo G

Publication Date: 2017-11-20

Variant appearance in text: TET2: 1771C>T; Gln591Ter

PubMed Link: 29235468

Variant Present in the following documents:

• 41408_2017_16_MOESM1_ESM.pdf

View BVdb publication page

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A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors.

Scientific Reports

Katigbak, Alexandra A; Cencic, Regina R; Robert, Francis F; Sénécha, Patrick P; Scuoppo, Claudio C; Pelletier, Jerry J

Publication Date: 2016-12-16

Variant appearance in text: TET2: Q591*

PubMed Link: 27982060

Variant Present in the following documents:

• srep38968-s2.xls, sheet 1

View BVdb publication page

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Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing.

Plos One

Hiemenz, Matthew C MC; Kadauke, Stephan S; Lieberman, David B DB; Roth, David B DB; Zhao, Jianhua J; Watt, Christopher D CD; Daber, Robert D RD; Morrissette, Jennifer J D JJ

Publication Date: 2016

Variant appearance in text: TET2: 1771C>T; Q591X

PubMed Link: 27043212

Variant Present in the following documents:

• pone.0152851.s001.xlsx, sheet 5
• pone.0152851.s001.xlsx, sheet 4

View BVdb publication page

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Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.

The Journal Of Experimental Medicine

Muto, Tomoya T; Sashida, Goro G; Oshima, Motohiko M; Wendt, George R GR; Mochizuki-Kashio, Makiko M; Nagata, Yasunobu Y; Sanada, Masashi M; Miyagi, Satoru S; Saraya, Atsunori A; Kamio, Asuka A; Nagae, Genta G; Nakaseko, Chiaki C; Yokote, Koutaro K; Shimoda, Kazuya K; Koseki, Haruhiko H; Suzuki, Yutaka Y; Sugano, Sumio S; Aburatani, Hiroyuki H; Ogawa, Seishi S; Iwama, Atsushi A

Publication Date: 2013-11-18

Variant appearance in text: TET2: Q591X

PubMed Link: 24218139

Variant Present in the following documents:

• supp_jem.20131144_JEM_20131144_sm.pdf

View BVdb publication page

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