TET2 c.2474del ;(p.S825*)

Variant ID: 4-106157573-TC-T

NM_001127208.2(TET2):c.2474del;(p.S825*)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology
,
Publication Date: 2022-11-24

Variant appearance in text: TET2: 2474del; S825*
PubMed Link: 36436542
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum.

Blood Advances
Calvo, Xavier X; Roman-Bravo, David D; Garcia-Gisbert, Nieves N; Rodriguez-Sevilla, Juan Jose JJ; Garcia-Avila, Sara S; Florensa, Lourdes L; Gibert, Joan J; Fernández-Rodríguez, Concepción C; Salido, Marta M; Puiggros, Anna A; Espinet, Blanca B; Colomo, Luis L; Bellosillo, Beatriz B; Ferrer, Ana A; Arenillas, Leonor L
Publication Date: 2022-07-12

Variant appearance in text: TET2: 2474delC; Ser825Ter
PubMed Link: 35709473
Variant Present in the following documents:
  • advancesADV2022007359-suppl1.pdf
View BVdb publication page



Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease.

Leukemia
Dawoud, Ahmed A Z AAZ; Gilbert, Rodney D RD; Tapper, William J WJ; Cross, Nicholas C P NCP
Publication Date: 2022-02

Variant appearance in text: TET2: 2474delC; S825*
PubMed Link: 34413458
Variant Present in the following documents:
  • 41375_2021_1382_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Hereditary cancer syndrome-associated pathogenic variants are common in patients with hematologic malignancies subsequent to primary solid cancer.

Journal Of Cancer
Oh, Joowon J; Kim, Yu Ri YR; Kim, Yoonjung Y; Kim, Boyeon B; Park, Kyung Sun KS; Nam, Seong-Hyeuk SH; Lee, Kyung-A KA
Publication Date: 2021

Variant appearance in text: TET2: 2474del
PubMed Link: 34093829
Variant Present in the following documents:
  • jcav12p4288s2.xlsx, sheet 3
View BVdb publication page



Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Clinical And Translational Medicine
Li, Ziyang Z; Huang, Wensou W; Yin, Jiani C JC; Na, Chenglong C; Wu, Xue X; Shao, Yang Y; Ding, Huaxin H; Li, Jinming J
Publication Date: 2020-11

Variant appearance in text: TET2: 2474delC; S825X
PubMed Link: 33252848
Variant Present in the following documents:
  • CTM2-10-e222-s003.xlsx, sheet 1
View BVdb publication page



Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance.

Haematologica
Mikkelsen, Stine U SU; Safavi, Setareh S; Dimopoulos, Konstantinos K; O'Rourke, Colm J CJ; Andersen, Mette K MK; Holm, Mette S MS; Marcher, Claus W CW; Andersen, Jesper B JB; Hansen, Jakob W JW; Grønbæk, Kirsten K
Publication Date: 2021-06-01

Variant appearance in text: TET2: 2474_2474delC; Ser825fs
PubMed Link: 33179473
Variant Present in the following documents:
  • 2020_263319_MIKKELSEN_SUPPL.pdf
View BVdb publication page



Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19.

Cancers
Duployez, Nicolas N; Demonchy, Jordane J; Berthon, Céline C; Goutay, Julien J; Caplan, Morgan M; Moreau, Anne-Sophie AS; Bignon, Anne A; Marceau-Renaut, Alice A; Garrigue, Delphine D; Raczkiewicz, Imelda I; Geffroy, Sandrine S; Bucci, Maxime M; Alidjinou, Kazali K; Demaret, Julie J; Labalette, Myriam M; Brousseau, Thierry T; Dupont, Annabelle A; Rauch, Antoine A; Poissy, Julien J; Susen, Sophie S; Preudhomme, Claude C; Quesnel, Bruno B
Publication Date: 2020-07-21

Variant appearance in text: TET2: 2474del; S825X
PubMed Link: 32708264
Variant Present in the following documents:
  • cancers-12-01992-s001.pdf
View BVdb publication page



Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design.

Plos One
Aguilera-Diaz, Almudena A; Vazquez, Iria I; Ariceta, Beñat B; Mañú, Amagoia A; Blasco-Iturri, Zuriñe Z; Palomino-Echeverría, Sara S; Larrayoz, María José MJ; García-Sanz, Ramón R; Prieto-Conde, María Isabel MI; Del Carmen Chillón, María M; Alfonso-Pierola, Ana A; Prosper, Felipe F; Fernandez-Mercado, Marta M; Calasanz, María José MJ
Publication Date: 2020

Variant appearance in text: TET2: 2474delC
PubMed Link: 31978184
Variant Present in the following documents:
  • pone.0227986.pdf
View BVdb publication page



Functional genomic landscape of acute myeloid leukaemia.

Nature
Tyner, Jeffrey W JW; Tognon, Cristina E CE; Bottomly, Daniel D; Wilmot, Beth B; Kurtz, Stephen E SE; Savage, Samantha L SL; Long, Nicola N; Schultz, Anna Reister AR; Traer, Elie E; Abel, Melissa M; Agarwal, Anupriya A; Blucher, Aurora A; Borate, Uma U; Bryant, Jade J; Burke, Russell R; Carlos, Amy A; Carpenter, Richie R; Carroll, Joseph J; Chang, Bill H BH; Coblentz, Cody C; d'Almeida, Amanda A; Cook, Rachel R; Danilov, Alexey A; Dao, Kim-Hien T KT; Degnin, Michie M; Devine, Deirdre D; Dibb, James J; Edwards, David K DK; Eide, Christopher A CA; English, Isabel I; Glover, Jason J; Henson, Rachel R; Ho, Hibery H; Jemal, Abdusebur A; Johnson, Kara K; Johnson, Ryan R; Junio, Brian B; Kaempf, Andy A; Leonard, Jessica J; Lin, Chenwei C; Liu, Selina Qiuying SQ; Lo, Pierrette P; Loriaux, Marc M MM; Luty, Samuel S; Macey, Tara T; MacManiman, Jason J; Martinez, Jacqueline J; Mori, Motomi M; Nelson, Dylan D; Nichols, Ceilidh C; Peters, Jill J; Ramsdill, Justin J; Rofelty, Angela A; Schuff, Robert R; Searles, Robert R; Segerdell, Erik E; Smith, Rebecca L RL; Spurgeon, Stephen E SE; Sweeney, Tyler T; Thapa, Aashis A; Visser, Corinne C; Wagner, Jake J; Watanabe-Smith, Kevin K; Werth, Kristen K; Wolf, Joelle J; White, Libbey L; Yates, Amy A; Zhang, Haijiao H; Cogle, Christopher R CR; Collins, Robert H RH; Connolly, Denise C DC; Deininger, Michael W MW; Drusbosky, Leylah L; Hourigan, Christopher S CS; Jordan, Craig T CT; Kropf, Patricia P; Lin, Tara L TL; Martinez, Micaela E ME; Medeiros, Bruno C BC; Pallapati, Rachel R RR; Pollyea, Daniel A DA; Swords, Ronan T RT; Watts, Justin M JM; Weir, Scott J SJ; Wiest, David L DL; Winters, Ryan M RM; McWeeney, Shannon K SK; Druker, Brian J BJ
Publication Date: 2018-10

Variant appearance in text: TET2: 2474delC; Ser825Ter
PubMed Link: 30333627
Variant Present in the following documents:
  • NIHMS1504008-supplement-Supplementary_Tables_S1-S22.xlsx, sheet 7
  • NIHMS1504008-supplement-Supplementary_Tables_S1-S22.xlsx, sheet 16
View BVdb publication page



Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.

Oncotarget
Tarlock, Katherine K; Zhong, Shan S; He, Yuting Y; Ries, Rhonda R; Severson, Eric E; Bailey, Mark M; Morley, Samantha S; Balasubramanian, Sohail S; Erlich, Rachel R; Lipson, Doron D; Otto, Geoff A GA; Vergillo, Jo-Anne JA; Kolb, E Anders EA; Ross, Jeffrey S JS; Mughal, Tariq T; Stephens, Philip J PJ; Miller, Vincent V; Meshinchi, Soheil S; He, Jie J
Publication Date: 2018-05-29

Variant appearance in text: TET2: 2474_2474delC; S825fs*1
PubMed Link: 29899868
Variant Present in the following documents:
  • oncotarget-09-26417-s005.xlsx, sheet 1
View BVdb publication page



Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial.

Oncotarget
Renneville, Aline A; Abdelali, Raouf Ben RB; Chevret, Sylvie S; Nibourel, Olivier O; Cheok, Meyling M; Pautas, Cécile C; Duléry, Rémy R; Boyer, Thomas T; Cayuela, Jean-Michel JM; Hayette, Sandrine S; Raffoux, Emmanuel E; Farhat, Hassan H; Boissel, Nicolas N; Terre, Christine C; Dombret, Hervé H; Castaigne, Sylvie S; Preudhomme, Claude C
Publication Date: 2014-02-28

Variant appearance in text: TET2: 2474delC; S825X
PubMed Link: 24659740
Variant Present in the following documents:
  • oncotarget-05-916-s001.pdf
View BVdb publication page