Publications:

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: TET2: K1299N

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4

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The longitudinal dynamics and natural history of clonal haematopoiesis.

Nature

Fabre, Margarete A MA; de Almeida, José Guilherme JG; Fiorillo, Edoardo E; Mitchell, Emily E; Damaskou, Aristi A; Rak, Justyna J; Orrù, Valeria V; Marongiu, Michele M; Chapman, Michael Spencer MS; Vijayabaskar, M S MS; Baxter, Joanna J; Hardy, Claire C; Abascal, Federico F; Williams, Nicholas N; Nangalia, Jyoti J; Martincorena, Iñigo I; Campbell, Peter J PJ; McKinney, Eoin F EF; Cucca, Francesco F; Gerstung, Moritz M; Vassiliou, George S GS

Publication Date: 2022-06

Variant appearance in text: TET2: K1299N

PubMed Link: 35650444

Variant Present in the following documents:

• 41586_2022_4785_MOESM12_ESM.xlsx, sheet 1

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USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2.

Science Advances

Chen, Lei-Lei LL; Smith, Matthew D MD; Lv, Lei L; Nakagawa, Tadashi T; Li, Zhijun Z; Sun, Shao-Cong SC; Brown, Nicholas G NG; Xiong, Yue Y; Xu, Yan-Ping YP

Publication Date: 2020-09

Variant appearance in text: TET2: K1299N

PubMed Link: 32948596

Variant Present in the following documents:

• Main text
• abc9730.pdf
• abc9730_SM.pdf

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USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2.

Science Advances

Chen, Lei-Lei LL; Smith, Matthew D MD; Lv, Lei L; Nakagawa, Tadashi T; Li, Zhijun Z; Sun, Shao-Cong SC; Brown, Nicholas G NG; Xiong, Yue Y; Xu, Yan-Ping YP

Publication Date: 2020-09

Variant appearance in text: TET2: K1299N

PubMed Link: 32948596

Variant Present in the following documents:

• Main text
• abc9730_SM.pdf
• abc9730.pdf

View BVdb publication page

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TET2 missense variants in human neoplasia. A proposal of structural and functional classification.

Molecular Genetics & Genomic Medicine

Bussaglia, Elena E; Antón, Rosa R; Nomdedéu, Josep F JF; Fuentes-Prior, Pablo P

Publication Date: 2019-07

Variant appearance in text: TET2: 3897G>C; Lys1299Asn

PubMed Link: 31187595

Variant Present in the following documents:

View BVdb publication page

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DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor.

Journal Of Molecular Cell Biology

Schabla, N Max NM; Mondal, Koushik K; Swanson, Patrick C PC

Publication Date: 2019-09-19

Variant appearance in text: TET2: K1299N

PubMed Link: 30590706

Variant Present in the following documents:

• Main text
• mjy085.pdf

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Vpr Targets TET2 for Degradation by CRL4VprBP E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication.

Molecular Cell

Lv, Lei L; Wang, Qi Q; Xu, Yanping Y; Tsao, Li-Chung LC; Nakagawa, Tadashi T; Guo, Haitao H; Su, Lishan L; Xiong, Yue Y

Publication Date: 2018-06-07

Variant appearance in text: TET2: K1299N

PubMed Link: 29883611

Variant Present in the following documents:

• Main text

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TET2: K1299N

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 4

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The TET2 interactors and their links to hematological malignancies.

Iubmb Life

Pan, Feng F; Weeks, Ophelia O; Yang, Feng-Chun FC; Xu, Mingjiang M

Publication Date: 2015-06

Variant appearance in text: TET2: K1299N

PubMed Link: 26099018

Variant Present in the following documents:

• Main text

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CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.

Molecular Cell

Nakagawa, Tadashi T; Lv, Lei L; Nakagawa, Makiko M; Yu, Yanbao Y; Yu, Chao C; D'Alessio, Ana C AC; Nakayama, Keiko K; Fan, Heng-Yu HY; Chen, Xian X; Xiong, Yue Y

Publication Date: 2015-01-22

Variant appearance in text: TET2: K1299N

PubMed Link: 25557551

Variant Present in the following documents:

• Main text

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Feature-based classification of amino acid substitutions outside conserved functional protein domains.

Thescientificworldjournal

Gemovic, Branislava B; Perovic, Vladimir V; Glisic, Sanja S; Veljkovic, Nevena N

Publication Date: 2013

Variant appearance in text: TET2: K1299N

PubMed Link: 24348198

Variant Present in the following documents:

• 948617.f1.pdf

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Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms.

Blood

Jankowska, Anna M AM; Szpurka, Hadrian H; Tiu, Ramon V RV; Makishima, Hideki H; Afable, Manuel M; Huh, Jungwon J; O'Keefe, Christine L CL; Ganetzky, Rebecca R; McDevitt, Michael A MA; Maciejewski, Jaroslaw P JP

Publication Date: 2009-06-18

Variant appearance in text: TET2: K1299N

PubMed Link: 19372255

Variant Present in the following documents:

• Main text

View BVdb publication page

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