TET2 c.4977T>G ;(p.Y1659*)

Variant ID: 4-106196644-T-G

NM_001127208.2(TET2):c.4977T>G;(p.Y1659*)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: TET2: Y1659*
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease.

Leukemia
Dawoud, Ahmed A Z AAZ; Gilbert, Rodney D RD; Tapper, William J WJ; Cross, Nicholas C P NCP
Publication Date: 2022-02

Variant appearance in text: TET2: Y1659X
PubMed Link: 34413458
Variant Present in the following documents:
  • 41375_2021_1382_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



CEOP/IVE/GDP alternating regimen compared with CEOP as the first-line therapy for newly diagnosed patients with peripheral T cell lymphoma: results from a phase 2, multicenter, randomized, controlled clinical trial.

Genome Medicine
Cai, Ming-Ci MC; Cheng, Shu S; Wang, Xin X; Hu, Jian-Da JD; Song, Yong-Ping YP; Huang, Yao-Hui YH; Yan, Zi-Xun ZX; Jiang, Yu-Jie YJ; Fang, Xiao-Sheng XS; Zheng, Xiao-Yun XY; Dong, Li-Hua LH; Ji, Meng-Meng MM; Wang, Li L; Xu, Peng-Peng PP; Zhao, Wei-Li WL
Publication Date: 2020-04-30

Variant appearance in text: TET2: Y1659X
PubMed Link: 32349779
Variant Present in the following documents:
  • 13073_2020_739_MOESM1_ESM.pdf
View BVdb publication page



Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes.

Nature Communications
Nagata, Yasunobu Y; Makishima, Hideki H; Kerr, Cassandra M CM; Przychodzen, Bartlomiej P BP; Aly, Mai M; Goyal, Abhinav A; Awada, Hassan H; Asad, Mohammad Fahad MF; Kuzmanovic, Teodora T; Suzuki, Hiromichi H; Yoshizato, Tetsuichi T; Yoshida, Kenichi K; Chiba, Kenichi K; Tanaka, Hiroko H; Shiraishi, Yuichi Y; Miyano, Satoru S; Mukherjee, Sudipto S; LaFramboise, Thomas T; Nazha, Aziz A; Sekeres, Mikkael A MA; Radivoyevitch, Tomas T; Haferlach, Torsten T; Ogawa, Seishi S; Maciejewski, Jaroslaw P JP
Publication Date: 2019-11-26

Variant appearance in text: TET2: Y1659X
PubMed Link: 31772163
Variant Present in the following documents:
  • 41467_2019_13001_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis.

Leukemia
Tefferi, A A; Pardanani, A A; Lim, K-H KH; Abdel-Wahab, O O; Lasho, T L TL; Patel, J J; Gangat, N N; Finke, C M CM; Schwager, S S; Mullally, A A; Li, C-Y CY; Hanson, C A CA; Mesa, R R; Bernard, O O; Delhommeau, F F; Vainchenker, W W; Gilliland, D G DG; Levine, R L RL
Publication Date: 2009-05

Variant appearance in text: TET2: Y1659X
PubMed Link: 19262601
Variant Present in the following documents:
  • Main text
View BVdb publication page