Publications:

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Genomic landscape and efficacy of HER2-targeted therapy in patients with HER2-mutant non-small cell lung cancer.

Frontiers In Oncology

Han, Yanjie Y; Xiong, Yuanyuan Y; Lu, Tao T; Chen, Rongrong R; Liu, Yuan Y; Tang, Hui H; Geng, Ruixuan R; Wang, Yingyi Y

Publication Date: 2023

Variant appearance in text: TET2: H1881R

PubMed Link: 37077822

Variant Present in the following documents:

• fonc-13-1121708.pdf

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: TET2: 5642A>G; H1881R

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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CNL and aCML should be considered as single entity based on molecular profiles and outcomes.

Blood Advances

Carreño-Tarragona, Gonzalo G; Alvarez-Larran, Alberto A; Harrison, Claire N CN; Martínez-Ávila, José Carlos JC; Hernandez-Boluda, Juan Carlos JC; Ferrer-Marin, Francisca F; Radia, Deepti H DH; Mora Casterá, Elvira E; Francis, Sebastian S; González-Martínez, Teresa T; Goddard, Kathryn K; Perez-Encinas, Manuel M; Narayanan, Srinivasan S; Raya, Jose Maria JM; Singh, Vikram V; Toth, Peter P; Gutiérrez, Xabier X; Amat Martinez, Paula P; McIlwaine, Louisa L; Alobaidi, Magda M; Mayani, Karan K; McGregor, Andrew A; Stuckey, Ruth R; Psaila, Bethan B; Segura, Adrian A; Alvares, Caroline L CL; Davidson, Kerri K; Osorio, Santiago S; Cutting, Robert R; Sweeney, Caroline P CP; Rufian, Laura L; Moreno, Laura L; Cuenca, Isabel I; Smith, Jeffrey J; Morales, María Luz ML; Gil-Manso, Rodrigo R; Koutsavlis, Ioannis I; Wang, Lihui L; Mead, Adam J AJ; Rozman, Maria M; Martínez-López, Joaquin J; Ayala, Rosa R; Cross, Nicholas Cp NC

Publication Date: 2022-11-14

Variant appearance in text: TET2: 5642A>G; H1881R

PubMed Link: 36375042

Variant Present in the following documents:

• BLOODA_ADV-2022-008204-mmc1.pdf

View BVdb publication page

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Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years.

Geroscience

Del Pozo-Valero, Marta M; Corton, Marta M; López-Rodríguez, Rosario R; Mahillo-Fernández, Ignacio I; Ruiz-Hornillos, Javier J; Minguez, Pablo P; Villaverde, Cristina C; Pérez-Tomás, María Elena ME; Barreda-Sánchez, María M; Mancebo, Esther E; , ; Paz-Artal, Estela E; Guillén-Navarro, Encarna E; Almoguera, Berta B; Ayuso, Carmen C

Publication Date: 2022-10-03

Variant appearance in text: TET2: 5642A>G; His1881Arg

PubMed Link: 36184726

Variant Present in the following documents:

• 11357_2022_666_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: TET2: H1881R

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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The longitudinal dynamics and natural history of clonal haematopoiesis.

Nature

Fabre, Margarete A MA; de Almeida, José Guilherme JG; Fiorillo, Edoardo E; Mitchell, Emily E; Damaskou, Aristi A; Rak, Justyna J; Orrù, Valeria V; Marongiu, Michele M; Chapman, Michael Spencer MS; Vijayabaskar, M S MS; Baxter, Joanna J; Hardy, Claire C; Abascal, Federico F; Williams, Nicholas N; Nangalia, Jyoti J; Martincorena, Iñigo I; Campbell, Peter J PJ; McKinney, Eoin F EF; Cucca, Francesco F; Gerstung, Moritz M; Vassiliou, George S GS

Publication Date: 2022-06

Variant appearance in text: TET2: H1881R

PubMed Link: 35650444

Variant Present in the following documents:

• 41586_2022_4785_MOESM11_ESM.xlsx, sheet 1
• 41586_2022_4785_MOESM9_ESM.xlsx, sheet 1
• 41586_2022_4785_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One

Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S

Publication Date: 2022

Variant appearance in text: TET2: H1881R

PubMed Link: 35358259

Variant Present in the following documents:

• pone.0266112.s001.xlsx, sheet 1

View BVdb publication page

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Next-generation sequencing in thyroid cancers: do targetable alterations lead to a therapeutic advantage?: A multicenter experience.

Medicine

Moore, Assaf A; Bar, Yael Y; Maurice-Dror, Corinne C; Finkel, Inbar I; Goldvaser, Hadar H; Dudnik, Elizabeth E; Goldstein, Daniel A DA; Gordon, Noa N; Billan, Salem S; Gutfeld, Orit O; Wolf, Ido I; Popovtzer, Aron A

Publication Date: 2021-06-25

Variant appearance in text: TET2: H1881R

PubMed Link: 34160418

Variant Present in the following documents:

• Main text
• medi-100-e26388.pdf

View BVdb publication page

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A noncanonical AR addiction drives enzalutamide resistance in prostate cancer.

Nature Communications

He, Yundong Y; Wei, Ting T; Ye, Zhenqing Z; Orme, Jacob J JJ; Lin, Dong D; Sheng, Haoyue H; Fazli, Ladan L; Jeffrey Karnes, R R; Jimenez, Rafael R; Wang, Liguo L; Wang, Liewei L; Gleave, Martin E ME; Wang, Yuzhuo Y; Shi, Lei L; Huang, Haojie H

Publication Date: 2021-03-09

Variant appearance in text: TET2: H1881R

PubMed Link: 33750801

Variant Present in the following documents:

• Main text
• 41467_2021_21860_MOESM1_ESM.pdf
• 41467_2021_Article_21860.pdf
• 41467_2021_21860_MOESM2_ESM.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TET2: 5642A>G; H1881R

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Kidney cancer PDOXs reveal patient-specific pro-malignant effects of antiangiogenics and its molecular traits.

Embo Molecular Medicine

Moserle, Lidia L; Pons, Roser R; Martínez-Lozano, Mar M; Jiménez-Valerio, Gabriela A GA; Vidal, August A; Suárez, Cristina C; Trilla, Enrique E; Jiménez, José J; de Torres, Inés I; Carles, Joan J; Senserrich, Jordi J; Aguilar, Susana S; Palomero, Luis L; Amadori, Alberto A; Casanovas, Oriol O

Publication Date: 2020-12-07

Variant appearance in text: TET2: 5642A>G; rs1417392445

PubMed Link: 33151035

Variant Present in the following documents:

• EMMM-12-e11889-s001.pdf

View BVdb publication page

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Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes.

Nature Communications

Nagata, Yasunobu Y; Makishima, Hideki H; Kerr, Cassandra M CM; Przychodzen, Bartlomiej P BP; Aly, Mai M; Goyal, Abhinav A; Awada, Hassan H; Asad, Mohammad Fahad MF; Kuzmanovic, Teodora T; Suzuki, Hiromichi H; Yoshizato, Tetsuichi T; Yoshida, Kenichi K; Chiba, Kenichi K; Tanaka, Hiroko H; Shiraishi, Yuichi Y; Miyano, Satoru S; Mukherjee, Sudipto S; LaFramboise, Thomas T; Nazha, Aziz A; Sekeres, Mikkael A MA; Radivoyevitch, Tomas T; Haferlach, Torsten T; Ogawa, Seishi S; Maciejewski, Jaroslaw P JP

Publication Date: 2019-11-26

Variant appearance in text: TET2: H1881R

PubMed Link: 31772163

Variant Present in the following documents:

• 41467_2019_13001_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias.

Mayo Clinic Proceedings

Mangaonkar, Abhishek A AA; Ferrer, Alejandro A; Pinto E Vairo, Filippo F; Cousin, Margot A MA; Kuisle, Ryan J RJ; Gangat, Naseema N; Hogan, William J WJ; Litzow, Mark R MR; McAllister, Tammy M TM; Klee, Eric W EW; Lazaridis, Konstantinos N KN; Stewart, A Keith AK; Patnaik, Mrinal M MM

Publication Date: 2019-09

Variant appearance in text: TET2: 5642A>G

PubMed Link: 31256854

Variant Present in the following documents:

• Main text

View BVdb publication page

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TET2 missense variants in human neoplasia. A proposal of structural and functional classification.

Molecular Genetics & Genomic Medicine

Bussaglia, Elena E; Antón, Rosa R; Nomdedéu, Josep F JF; Fuentes-Prior, Pablo P

Publication Date: 2019-07

Variant appearance in text: TET2: His1881Arg

PubMed Link: 31187595

Variant Present in the following documents:

• Main text
• MGG3-7-e00772.pdf

View BVdb publication page

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Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Coombs, Catherine C CC; Gillis, Nancy K NK; Tan, Xianming X; Berg, Jonathan S JS; Ball, Markus M; Balasis, Maria E ME; Montgomery, Nathan D ND; Bolton, Kelly L KL; Parker, Joel S JS; Mesa, Tania E TE; Yoder, Sean J SJ; Hayward, Michele C MC; Patel, Nirali M NM; Richards, Kristy L KL; Walko, Christine M CM; Knepper, Todd C TC; Soper, John T JT; Weiss, Jared J; Grilley-Olson, Juneko E JE; Kim, William Y WY; Earp, H Shelton HS; Levine, Ross L RL; Papaemmanuil, Elli E; Zehir, Ahmet A; Hayes, D Neil DN; Padron, Eric E

Publication Date: 2018-12-01

Variant appearance in text: TET2: H1881R

PubMed Link: 29866652

Variant Present in the following documents:

• Main text

View BVdb publication page

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The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.

Journal Of Biochemistry

Yamagata, Kazuyuki K; Kobayashi, Akira A

Publication Date: 2017-04-01

Variant appearance in text: TET2: H1881R

PubMed Link: 28130413

Variant Present in the following documents:

• Main text
• mvx004.pdf

View BVdb publication page

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Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

The Journal Of Biological Chemistry

Laukka, Tuomas T; Mariani, Christopher J CJ; Ihantola, Tuukka T; Cao, John Z JZ; Hokkanen, Juho J; Kaelin, William G WG; Godley, Lucy A LA; Koivunen, Peppi P

Publication Date: 2016-02-19

Variant appearance in text: TET2: H1881R

PubMed Link: 26703470

Variant Present in the following documents:

• Main text

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TET2: H1881R

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 4

View BVdb publication page

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Feature-based classification of amino acid substitutions outside conserved functional protein domains.

Thescientificworldjournal

Gemovic, Branislava B; Perovic, Vladimir V; Glisic, Sanja S; Veljkovic, Nevena N

Publication Date: 2013

Variant appearance in text: TET2: H1881R

PubMed Link: 24348198

Variant Present in the following documents:

• 948617.f1.pdf

View BVdb publication page

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Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.

Blood

Abdel-Wahab, Omar O; Mullally, Ann A; Hedvat, Cyrus C; Garcia-Manero, Guillermo G; Patel, Jay J; Wadleigh, Martha M; Malinge, Sebastien S; Yao, JinJuan J; Kilpivaara, Outi O; Bhat, Rukhmi R; Huberman, Kety K; Thomas, Sabrena S; Dolgalev, Igor I; Heguy, Adriana A; Paietta, Elisabeth E; Le Beau, Michelle M MM; Beran, Miloslav M; Tallman, Martin S MS; Ebert, Benjamin L BL; Kantarjian, Hagop M HM; Stone, Richard M RM; Gilliland, D Gary DG; Crispino, John D JD; Levine, Ross L RL

Publication Date: 2009-07-02

Variant appearance in text: TET2: H1881R

PubMed Link: 19420352

Variant Present in the following documents:

• Main text

View BVdb publication page

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Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates.

Leukemia

Tefferi, A A; Levine, R L RL; Lim, K-H KH; Abdel-Wahab, O O; Lasho, T L TL; Patel, J J; Finke, C M CM; Mullally, A A; Li, C-Y CY; Pardanani, A A; Gilliland, D G DG

Publication Date: 2009-05

Variant appearance in text: TET2: H1881R

PubMed Link: 19262599

Variant Present in the following documents:

• Main text

View BVdb publication page

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