METTL14 c.893G>C ;(p.R298P)

Variant ID: 4-119626803-G-C

NM_020961.2(METTL14):c.893G>C;(p.R298P)

This variant was identified in 46 publications

View GRCh38 version.




Publications:


Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: METTL14: R298P
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 5
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
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RNA N6-methyladenosine modification in female reproductive biology and pathophysiology.

Cell Communication And Signaling : Ccs
Huang, Erqing E; Chen, Lijuan L
Publication Date: 2023-03-09

Variant appearance in text: METTL14: R298P
PubMed Link: 36894952
Variant Present in the following documents:
  • Main text
  • 12964_2023_Article_1078.pdf
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Opposing regulation of the Nα-trimethylase METTL11A by its family members METTL11B and METTL13.

The Journal Of Biological Chemistry
Parker, HaleyV H; Schaner Tooley, ChristineE C
Publication Date: 2023-03-06

Variant appearance in text: METTL14: R298P
PubMed Link: 36889590
Variant Present in the following documents:
  • Main text
  • main.pdf
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METTL14 modulates glycolysis to inhibit colorectal tumorigenesis in p53-wild-type cells.

Embo Reports
Hou, Yichao Y; Zhang, Xintian X; Yao, Han H; Hou, Lidan L; Zhang, Qingwei Q; Tao, Enwei E; Zhu, Xiaoqiang X; Jiang, Shanshan S; Ren, Yimeng Y; Hong, Xialu X; Lu, Shiyuan S; Leng, Xiaoxu X; Xie, Yile Y; Gao, Yaqi Y; Liang, Yu Y; Zhong, Ting T; Long, Bohan B; Fang, Jing-Yuan JY; Meng, Xiangjun X
Publication Date: 2023-02-16

Variant appearance in text: METTL14: R298P
PubMed Link: 36794620
Variant Present in the following documents:
  • Main text
  • EMBR-24-e56325.pdf
  • EMBR-24-e56325-s001.pdf
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METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma.

Ebiomedicine
Li, Hong-Bo HB; Huang, Gang G; Tu, Jian J; Lv, Dong-Ming DM; Jin, Qing-Lin QL; Chen, Jun-Kai JK; Zou, Yu-Tong YT; Lee, Dung-Fang DF; Shen, Jing-Nan JN; Xie, Xian-Biao XB
Publication Date: 2022-08

Variant appearance in text: METTL14: R298P
PubMed Link: 35810559
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.

The Journal Of Clinical Investigation
Lee, Patrick C PC; Klaeger, Susan S; Le, Phuong M PM; Korthauer, Keegan K; Cheng, Jingwei J; Ananthapadmanabhan, Varsha V; Frost, Thomas C TC; Stevens, Jonathan D JD; Wong, Alan Yl AY; Iorgulescu, J Bryan JB; Tarren, Anna Y AY; Chea, Vipheaviny A VA; Carulli, Isabel P IP; Lemvigh, Camilla K CK; Pedersen, Christina B CB; Gartin, Ashley K AK; Sarkizova, Siranush S; Wright, Kyle T KT; Li, Letitia W LW; Nomburg, Jason J; Li, Shuqiang S; Huang, Teddy T; Liu, Xiaoxi X; Pomerance, Lucas L; Doherty, Laura M LM; Apffel, Annie M AM; Wallace, Luke J LJ; Rachimi, Suzanna S; Felt, Kristen D KD; Wolff, Jacquelyn O JO; Witten, Elizabeth E; Zhang, Wandi W; Neuberg, Donna D; Lane, William J WJ; Zhang, Guanglan G; Olsen, Lars R LR; Thakuria, Manisha M; Rodig, Scott J SJ; Clauser, Karl R KR; Starrett, Gabriel J GJ; Doench, John G JG; Buhrlage, Sara J SJ; Carr, Steven A SA; DeCaprio, James A JA; Wu, Catherine J CJ; Keskin, Derin B DB
Publication Date: 2022-07-01

Variant appearance in text: METTL14: R298P
PubMed Link: 35775490
Variant Present in the following documents:
  • jci-132-151666-s199.xlsx, sheet 1
View BVdb publication page



Functions, mechanisms, and therapeutic implications of METTL14 in human cancer.

Journal Of Hematology & Oncology
Guan, Qian Q; Lin, Huiran H; Miao, Lei L; Guo, Huiqin H; Chen, Yongping Y; Zhuo, Zhenjian Z; He, Jing J
Publication Date: 2022-02-03

Variant appearance in text: METTL14: R298P
PubMed Link: 35115038
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functions, mechanisms, and therapeutic implications of METTL14 in human cancer.

Journal Of Hematology & Oncology
Guan, Qian Q; Lin, Huiran H; Miao, Lei L; Guo, Huiqin H; Chen, Yongping Y; Zhuo, Zhenjian Z; He, Jing J
Publication Date: 2022-02-03

Variant appearance in text: METTL14: R298P
PubMed Link: 35115038
Variant Present in the following documents:
  • Main text
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: METTL14: R298P
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 4
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: METTL14: R298P
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 4
View BVdb publication page



METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination.

Molecular Therapy. Nucleic Acids
Shen, Danyang D; Ding, Lifeng L; Lu, Zeyi Z; Wang, Ruyue R; Yu, Chenhao C; Wang, Huan H; Zheng, Qiming Q; Wang, Xuliang X; Xu, Wanjiang W; Yu, Haifeng H; Xu, Liwei L; Wang, Mingchao M; Yu, Shicheng S; Zhu, Shibin S; Qian, Jun J; Xia, Liqun L; Li, Gonghui G
Publication Date: 2022-03-08

Variant appearance in text: METTL14: R298P
PubMed Link: 35036065
Variant Present in the following documents:
  • Main text
  • mmc2.pdf
  • main.pdf
View BVdb publication page



Increased METTL3-mediated m6A methylation inhibits embryo implantation by repressing HOXA10 expression in recurrent implantation failure.

Reproductive Biology And Endocrinology : Rb&E
Xue, Pingping P; Zhou, Wenbo W; Fan, Wenqiang W; Jiang, Jianya J; Kong, Chengcai C; Zhou, Wei W; Zhou, Jianmei J; Huang, Xiaoyang X; Yang, Haiyan H; Han, Qian Q; Zhang, Bin B; Xu, Lingyun L; Yu, Bin B; Chen, Li L
Publication Date: 2021-12-14

Variant appearance in text: METTL14: R298P
PubMed Link: 34906165
Variant Present in the following documents:
  • Main text
  • 12958_2021_Article_872.pdf
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Increased METTL3-mediated m6A methylation inhibits embryo implantation by repressing HOXA10 expression in recurrent implantation failure.

Reproductive Biology And Endocrinology : Rb&E
Xue, Pingping P; Zhou, Wenbo W; Fan, Wenqiang W; Jiang, Jianya J; Kong, Chengcai C; Zhou, Wei W; Zhou, Jianmei J; Huang, Xiaoyang X; Yang, Haiyan H; Han, Qian Q; Zhang, Bin B; Xu, Lingyun L; Yu, Bin B; Chen, Li L
Publication Date: 2021-12-14

Variant appearance in text: METTL14: R298P
PubMed Link: 34906165
Variant Present in the following documents:
  • Main text
  • 12958_2021_Article_872.pdf
View BVdb publication page



Insights into roles of METTL14 in tumors.

Cell Proliferation
Liu, Xin X; Du, Yuping Y; Huang, Zhenghao Z; Qin, Honglei H; Chen, Jingwen J; Zhao, Yang Y
Publication Date: 2021-12-13

Variant appearance in text: METTL14: R298P
PubMed Link: 34904301
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2-dependent silencing of SLC7A11.

Journal Of Cellular And Molecular Medicine
Fan, Zhuoyang Z; Yang, Guowei G; Zhang, Wei W; Liu, Qian Q; Liu, Guangqin G; Liu, Pingping P; Xu, Ligang L; Wang, Jianhua J; Yan, Zhiping Z; Han, Hong H; Liu, Rong R; Shu, Minfeng M
Publication Date: 2021-11

Variant appearance in text: METTL14: R298P
PubMed Link: 34609072
Variant Present in the following documents:
  • Main text
  • JCMM-25-10197.pdf
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TNF-α-mediated m6A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis.

Nature Communications
Xie, Zhongyu Z; Yu, Wenhui W; Zheng, Guan G; Li, Jinteng J; Cen, Shuizhong S; Ye, Guiwen G; Li, Zhaofeng Z; Liu, Wenjie W; Li, Ming M; Lin, Jiajie J; Su, Zepeng Z; Che, Yunshu Y; Ye, Feng F; Wang, Peng P; Wu, Yanfeng Y; Shen, Huiyong H
Publication Date: 2021-09-10

Variant appearance in text: METTL14: R298P
PubMed Link: 34508078
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_25710.pdf
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Immune infiltration-related N6-methyladenosine RNA methylation regulators influence the malignancy and prognosis of endometrial cancer.

Aging
Ma, Jian J; Yang, Di D; Ma, Xiao-Xin XX
Publication Date: 2021-06-16

Variant appearance in text: METTL14: R298P
PubMed Link: 34230220
Variant Present in the following documents:
  • Main text
  • aging-13-203157.pdf
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Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N6 -methyladenosine Modification.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Qin, Fei F; Cai, Baoshan B; Zhao, Jian J; Zhang, Lei L; Zheng, Yi Y; Liu, Bingyu B; Gao, Chengjiang C
Publication Date: 2021-08

Variant appearance in text: METTL14: R298P
PubMed Link: 34047074
Variant Present in the following documents:
  • Main text
View BVdb publication page



N6 -methyladenosine Steers RNA Metabolism and Regulation in Cancer.

Cancer Communications (London, England)
Dong, Shenghua S; Wu, Yutong Y; Liu, Yadi Y; Weng, Hengyou H; Huang, Huilin H
Publication Date: 2021-07

Variant appearance in text: METTL14: R298P
PubMed Link: 33955720
Variant Present in the following documents:
  • Main text
View BVdb publication page



N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies.

Journal Of Experimental & Clinical Cancer Research : Cr
Tan, Fenghua F; Zhao, Mengyao M; Xiong, Fang F; Wang, Yumin Y; Zhang, Shanshan S; Gong, Zhaojian Z; Li, Xiayu X; He, Yi Y; Shi, Lei L; Wang, Fuyan F; Xiang, Bo B; Zhou, Ming M; Li, Xiaoling X; Li, Yong Y; Li, Guiyuan G; Zeng, Zhaoyang Z; Xiong, Wei W; Guo, Can C
Publication Date: 2021-04-29

Variant appearance in text: METTL14: R298P
PubMed Link: 33926508
Variant Present in the following documents:
  • Main text
View BVdb publication page



RNA Epigenetics: Fine-Tuning Chromatin Plasticity and Transcriptional Regulation, and the Implications in Human Diseases.

Genes
Willbanks, Amber A; Wood, Shaun S; Cheng, Jason X JX
Publication Date: 2021-04-22

Variant appearance in text: METTL14: R298P
PubMed Link: 33922187
Variant Present in the following documents:
  • Main text
View BVdb publication page



Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications
Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L
Publication Date: 2021-04-19

Variant appearance in text: METTL14: R298P
PubMed Link: 33875650
Variant Present in the following documents:
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis.

Molecular Cancer
Uddin, Mohammad Burhan MB; Wang, Zhishan Z; Yang, Chengfeng C
Publication Date: 2021-04-04

Variant appearance in text: METTL14: R298P
PubMed Link: 33814008
Variant Present in the following documents:
  • Main text
View BVdb publication page



m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype.

Nature Cell Biology
Liu, Pingyu P; Li, Fuming F; Lin, Jianhuang J; Fukumoto, Takeshi T; Nacarelli, Timothy T; Hao, Xue X; Kossenkov, Andrew V AV; Simon, M Celeste MC; Zhang, Rugang R
Publication Date: 2021-04

Variant appearance in text: METTL14: R298P
PubMed Link: 33795874
Variant Present in the following documents:
  • Main text
  • nihms-1678412.pdf
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Downregulated METTL14 Expression Correlates with Breast Cancer Tumor Grade and Molecular Classification.

Biomed Research International
Dong, Xiao-Fang XF; Wang, Yan Y; Huang, Bi-Fei BF; Hu, Gui-Nv GN; Shao, Jun-Kang JK; Wang, Qian Q; Tang, Chih-Hsin CH; Wang, Chao-Qun CQ
Publication Date: 2020

Variant appearance in text: METTL14: R298P
PubMed Link: 33134390
Variant Present in the following documents:
  • Main text
  • BMRI2020-8823270.pdf
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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Frontiers In Immunology
Punta, Marco M; Jennings, Victoria A VA; Melcher, Alan A AA; Lise, Stefano S
Publication Date: 2020

Variant appearance in text: METTL14: R298P
PubMed Link: 33133066
Variant Present in the following documents:
  • Table_6.xlsx, sheet 7
  • Table_6.xlsx, sheet 2
  • Table_1.xlsx, sheet 2
View BVdb publication page



The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma.

Peerj
Tang, Rong R; Zhang, Yiyin Y; Liang, Chen C; Xu, Jin J; Meng, Qingcai Q; Hua, Jie J; Liu, Jiang J; Zhang, Bo B; Yu, Xianjun X; Shi, Si S
Publication Date: 2020

Variant appearance in text: METTL14: R298P
PubMed Link: 33062408
Variant Present in the following documents:
  • Main text
View BVdb publication page



N6 -methyladenosine (m6 A) RNA modification in human cancer.

Cell Proliferation
Huo, Fu-Chun FC; Zhu, Zhi-Man ZM; Pei, Dong-Sheng DS
Publication Date: 2020-11

Variant appearance in text: METTL14: R298P
PubMed Link: 33029866
Variant Present in the following documents:
  • Main text
  • CPR-53-e12921.pdf
View BVdb publication page



N6 -methyladenosine (m6A) RNA modification in human cancer.

Cell Proliferation
Huo, Fu-Chun FC; Zhu, Zhi-Man ZM; Pei, Dong-Sheng DS
Publication Date: 2020-11

Variant appearance in text: METTL14: R298P
PubMed Link: 33029866
Variant Present in the following documents:
  • Main text
  • CPR-53-e12921.pdf
View BVdb publication page



The emerging roles of N6-methyladenosine RNA methylation in human cancers.

Biomarker Research
Shen, Huafei H; Lan, Yifen Y; Zhao, Yanchun Y; Shi, Yuanfei Y; Jin, Jie J; Xie, Wanzhuo W
Publication Date: 2020

Variant appearance in text: METTL14: R298P
PubMed Link: 32612834
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanism of RNA modification N6-methyladenosine in human cancer.

Molecular Cancer
Zhou, Zijian Z; Lv, Jiancheng J; Yu, Hao H; Han, Jie J; Yang, Xiao X; Feng, Dexiang D; Wu, Qikai Q; Yuan, Baorui B; Lu, Qiang Q; Yang, Haiwei H
Publication Date: 2020-06-08

Variant appearance in text: METTL14: R298P
PubMed Link: 32513173
Variant Present in the following documents:
  • Main text
  • 12943_2020_Article_1216.pdf
View BVdb publication page



m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer.

Cancer Cell
Huang, Huilin H; Weng, Hengyou H; Chen, Jianjun J
Publication Date: 2020-03-16

Variant appearance in text: METTL14: R298P
PubMed Link: 32183948
Variant Present in the following documents:
  • Main text
View BVdb publication page



N6-Methyladenosine: A Potential Breakthrough for Human Cancer.

Molecular Therapy. Nucleic Acids
Liu, Lina L; Wang, Yuwei Y; Wu, Jie J; Liu, Jingwen J; Qin, Zongchang Z; Fan, Hong H
Publication Date: 2020-03-06

Variant appearance in text: METTL14: R298P
PubMed Link: 31958696
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



RNA N6-methyladenosine modification in solid tumors: new therapeutic frontiers.

Cancer Gene Therapy
Melstrom, Laleh L; Chen, Jianjun J
Publication Date: 2020-09

Variant appearance in text: METTL14: R298P
PubMed Link: 31956264
Variant Present in the following documents:
  • Main text
View BVdb publication page



Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology
Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M
Publication Date: 2020-01-07

Variant appearance in text: METTL14: R298P
PubMed Link: 31925297
Variant Present in the following documents:
  • 42003_2019_736_MOESM13_ESM.xlsx, sheet 1
View BVdb publication page



A large peptidome dataset improves HLA class I epitope prediction across most of the human population.

Nature Biotechnology
Sarkizova, Siranush S; Klaeger, Susan S; Le, Phuong M PM; Li, Letitia W LW; Oliveira, Giacomo G; Keshishian, Hasmik H; Hartigan, Christina R CR; Zhang, Wandi W; Braun, David A DA; Ligon, Keith L KL; Bachireddy, Pavan P; Zervantonakis, Ioannis K IK; Rosenbluth, Jennifer M JM; Ouspenskaia, Tamara T; Law, Travis T; Justesen, Sune S; Stevens, Jonathan J; Lane, William J WJ; Eisenhaure, Thomas T; Lan Zhang, Guang G; Clauser, Karl R KR; Hacohen, Nir N; Carr, Steven A SA; Wu, Catherine J CJ; Keskin, Derin B DB
Publication Date: 2020-02

Variant appearance in text: METTL14: R298P
PubMed Link: 31844290
Variant Present in the following documents:
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 86
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 91
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 20
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 92
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 90
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Identification of 12 cancer types through genome deep learning.

Scientific Reports
Sun, Yingshuai Y; Zhu, Sitao S; Ma, Kailong K; Liu, Weiqing W; Yue, Yao Y; Hu, Gang G; Lu, Huifang H; Chen, Wenbin W
Publication Date: 2019-11-21

Variant appearance in text: METTL14: R298P
PubMed Link: 31754222
Variant Present in the following documents:
  • 41598_2019_53989_MOESM4_ESM.xlsx, sheet 12
View BVdb publication page



Epigenetic Dysregulation at the Crossroad of Women's Cancer.

Cancers
Kumar, Rakesh R; Paul, Aswathy Mary AM; Rameshwar, Pranela P; Pillai, M Radhakrishna MR
Publication Date: 2019-08-16

Variant appearance in text: METTL14: R298P
PubMed Link: 31426393
Variant Present in the following documents:
  • Main text
  • cancers-11-01193.pdf
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Detailed modeling of positive selection improves detection of cancer driver genes.

Nature Communications
Zhao, Siming S; Liu, Jun J; Nanga, Pranav P; Liu, Yuwen Y; Cicek, A Ercument AE; Knoblauch, Nicholas N; He, Chuan C; Stephens, Matthew M; He, Xin X
Publication Date: 2019-07-30

Variant appearance in text: METTL14: R298P
PubMed Link: 31363082
Variant Present in the following documents:
  • Main text
  • 41467_2019_Article_11284.pdf
View BVdb publication page



Systematic analysis of the intersection of disease mutations with protein modifications.

Bmc Medical Genomics
Simpson, Claire M CM; Zhang, Bin B; Hornbeck, Peter V PV; Gnad, Florian F
Publication Date: 2019-07-25

Variant appearance in text: METTL14: R298P
PubMed Link: 31345222
Variant Present in the following documents:
  • 12920_2019_543_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Scientific Reports
Collord, Grace G; Tarpey, Patrick P; Kurbatova, Natalja N; Martincorena, Inigo I; Moran, Sebastian S; Castro, Manuel M; Nagy, Tibor T; Bignell, Graham G; Maura, Francesco F; Young, Matthew D MD; Berna, Jorge J; Tubio, Jose M C JMC; McMurran, Chris E CE; Young, Adam M H AMH; Sanders, Mathijs M; Noorani, Imran I; Price, Stephen J SJ; Watts, Colin C; Leipnitz, Elke E; Kirsch, Matthias M; Schackert, Gabriele G; Pearson, Danita D; Devadass, Abel A; Ram, Zvi Z; Collins, V Peter VP; Allinson, Kieren K; Jenkinson, Michael D MD; Zakaria, Rasheed R; Syed, Khaja K; Hanemann, C Oliver CO; Dunn, Jemma J; McDermott, Michael W MW; Kirollos, Ramez W RW; Vassiliou, George S GS; Esteller, Manel M; Behjati, Sam S; Brazma, Alvis A; Santarius, Thomas T; McDermott, Ultan U
Publication Date: 2018-09-10

Variant appearance in text: METTL14: R298P
PubMed Link: 30202034
Variant Present in the following documents:
  • 41598_2018_31659_MOESM2_ESM.xlsx, sheet 30
View BVdb publication page



m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.

Nature Cell Biology
Liu, Jun J; Eckert, Mark A MA; Harada, Bryan T BT; Liu, Song-Mei SM; Lu, Zhike Z; Yu, Kangkang K; Tienda, Samantha M SM; Chryplewicz, Agnieszka A; Zhu, Allen C AC; Yang, Ying Y; Huang, Jing-Tao JT; Chen, Shao-Min SM; Xu, Zhi-Gao ZG; Leng, Xiao-Hua XH; Yu, Xue-Chen XC; Cao, Jie J; Zhang, Zezhou Z; Liu, Jianzhao J; Lengyel, Ernst E; He, Chuan C
Publication Date: 2018-09

Variant appearance in text: METTL14: R298P
PubMed Link: 30154548
Variant Present in the following documents:
  • Main text
  • nihms-1500485.pdf
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METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.

Cell Stem Cell
Weng, Hengyou H; Huang, Huilin H; Wu, Huizhe H; Qin, Xi X; Zhao, Boxuan Simen BS; Dong, Lei L; Shi, Hailing H; Skibbe, Jennifer J; Shen, Chao C; Hu, Chao C; Sheng, Yue Y; Wang, Yungui Y; Wunderlich, Mark M; Zhang, Bin B; Dore, Louis C LC; Su, Rui R; Deng, Xiaolan X; Ferchen, Kyle K; Li, Chenying C; Sun, Miao M; Lu, Zhike Z; Jiang, Xi X; Marcucci, Guido G; Mulloy, James C JC; Yang, Jianhua J; Qian, Zhijian Z; Wei, Minjie M; He, Chuan C; Chen, Jianjun J
Publication Date: 2018-02-01

Variant appearance in text: METTL14: R298P
PubMed Link: 29290617
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutations in RNA methylating enzymes in disease.

Current Opinion In Chemical Biology
Stojković, Vanja V; Fujimori, Danica Galonić DG
Publication Date: 2017-12

Variant appearance in text: METTL14: Arg298Pro
PubMed Link: 29059606
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human m6A writers: Two subunits, 2 roles.

Rna Biology
Wang, Xiang X; Huang, Jinbo J; Zou, Tingting T; Yin, Ping P
Publication Date: 2017-03-04

Variant appearance in text: METTL14: R298P
PubMed Link: 28121234
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: METTL14: 893G>C; R298P
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

Plos Computational Biology
Bendl, Jaroslav J; Musil, Miloš M; Štourač, Jan J; Zendulka, Jaroslav J; Damborský, Jiří J; Brezovský, Jan J
Publication Date: 2016-05

Variant appearance in text: METTL14: R298P
PubMed Link: 27224906
Variant Present in the following documents:
  • pcbi.1004962.s005.xlsx, sheet 3
View BVdb publication page