FAT1 c.10510A>T ;(p.K3504*)

Variant ID: 4-187525569-T-A

NM_005245.3(FAT1):c.10510A>T;(p.K3504*)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma.

Bmc Medicine
Gu, Ziyue Z; Shi, Chaoji C; Li, Jiayi J; Han, Yong Y; Sun, Bao B; Zhang, Wuchang W; Wu, Jing J; Zhou, Guoyu G; Ye, Weimin W; Li, Jiang J; Zhang, Zhiyuan Z; Zhou, Rong R
Publication Date: 2022-05-12

Variant appearance in text: FAT1: 10510A>T; K3504X
PubMed Link: 35546399
Variant Present in the following documents:
  • 12916_2022_2373_MOESM2_ESM.xlsx, sheet 5
View BVdb publication page



EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1.

Communications Biology
Ando, Toshinori T; Arang, Nadia N; Wang, Zhiyong Z; Costea, Daniela Elena DE; Feng, Xiaodong X; Goto, Yusuke Y; Izumi, Hiroki H; Gilardi, Mara M; Ando, Kazuyo K; Gutkind, J Silvio JS
Publication Date: 2021-11-01

Variant appearance in text: FAT1: K3504X
PubMed Link: 34725466
Variant Present in the following documents:
  • Main text
  • 42003_2021_Article_2744.pdf
View BVdb publication page



Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Nature Communications
Martin, Daniel D; Degese, Maria S MS; Vitale-Cross, Lynn L; Iglesias-Bartolome, Ramiro R; Valera, Juan Luis Callejas JLC; Wang, Zhiyong Z; Feng, Xiaodong X; Yeerna, Huwate H; Vadmal, Vachan V; Moroishi, Toshiro T; Thorne, Rick F RF; Zaida, Moraima M; Siegele, Bradford B; Cheong, Sok C SC; Molinolo, Alfredo A AA; Samuels, Yardena Y; Tamayo, Pablo P; Guan, Kun Liang KL; Lippman, Scott M SM; Lyons, J Guy JG; Gutkind, J Silvio JS
Publication Date: 2018-07-09

Variant appearance in text: FAT1: K3504X
PubMed Link: 29985391
Variant Present in the following documents:
  • Main text
  • 41467_2018_Article_4590.pdf
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: FAT1: 10510A>T; K3504*
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 3
View BVdb publication page