Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.
Nature Communications
Shah, Jennifer B JB; Pueschl, Dana D; Wubbenhorst, Bradley B; Fan, Mengyao M; Pluta, John J; D'Andrea, Kurt K; Hubert, Anna P AP; Shilan, Jake S JS; Zhou, Wenting W; Kraya, Adam A AA; Llop Guevara, Alba A; Ruan, Catherine C; Serra, Violeta V; Balmaña, Judith J; Feldman, Michael M; Morin, Pat J PJ; Nayak, Anupma A; Maxwell, Kara N KN; Domchek, Susan M SM; Nathanson, Katherine L KL
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Cellular And Molecular Gastroenterology And Hepatology
Boos, Sophie L SL; Loevenich, Leon P LP; Vosberg, Sebastian S; Engleitner, Thomas T; Öllinger, Rupert R; Kumbrink, Jörg J; Rokavec, Matjaz M; Michl, Marlies M; Greif, Philipp A PA; Jung, Andreas A; Hermeking, Heiko H; Neumann, Jens J; Kirchner, Thomas T; Rad, Roland R; Jung, Peter P
Publication Date: 2022
Variant appearance in text: FAT1: 5383C>T; Arg1795Ter
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Cellular And Molecular Gastroenterology And Hepatology
Boos, Sophie L SL; Loevenich, Leon P LP; Vosberg, Sebastian S; Engleitner, Thomas T; Öllinger, Rupert R; Kumbrink, Jörg J; Rokavec, Matjaz M; Michl, Marlies M; Greif, Philipp A PA; Jung, Andreas A; Hermeking, Heiko H; Neumann, Jens J; Kirchner, Thomas T; Rad, Roland R; Jung, Peter P
Publication Date: 2021-10-23
Variant appearance in text: FAT1: 5383C>T; Arg1795Ter
A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.
Breast Cancer Research : Bcr
Kang, Taekyu T; Yau, Christina C; Wong, Christopher K CK; Sanborn, John Z JZ; Newton, Yulia Y; Vaske, Charlie C; Benz, Stephen C SC; Krings, Gregor G; Camarda, Roman R; Henry, Jill E JE; Stuart, Josh J; Powell, Mark M; Benz, Christopher C CC
Identification of relevant genetic alterations in cancer using topological data analysis.
Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM