KIT c.1679_1735del ;(p.V560_Y578del)

Variant ID: 4-55593610-TTGTTGAGGAGATAAATGGAAACAATTATGTTTACATAGACCCAACACAACTTCCTTA-T

NM_000222.2(KIT):c.1679_1735del;(p.V560_Y578del)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells.

Scientific Reports
Rausch, Jessica L JL; Ali, Areej A AA; Lee, Donna M DM; Gebreyohannes, Yemarshet K YK; Mehalek, Keith R KR; Agha, Aya A; Patil, Sneha S SS; Tolstov, Yanis Y; Wellens, Jasmien J; Dhillon, Harbir S HS; Makielski, Kathleen R KR; Debiec-Rychter, Maria M; Schöffski, Patrick P; Wozniak, Agnieszka A; Duensing, Anette A
Publication Date: 2020-03-20

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 32198455
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_62088.pdf
View BVdb publication page



Anti-KIT DNA Aptamer for Targeted Labeling of Gastrointestinal Stromal Tumor.

Molecular Cancer Therapeutics
Banerjee, Sudeep S; Yoon, Hyunho H; Yebra, Mayra M; Tang, Chih-Min CM; Gilardi, Mara M; Shankara Narayanan, Jayanth S JS; White, Rebekah R RR; Sicklick, Jason K JK; Ray, Partha P
Publication Date: 2020-05

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 32127469
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors.

Bmc Cancer
Serrano, César C; Vivancos, Ana A; López-Pousa, Antonio A; Matito, Judit J; Mancuso, Francesco M FM; Valverde, Claudia C; Quiroga, Sergi S; Landolfi, Stefania S; Castro, Sandra S; Dopazo, Cristina C; Sebio, Ana A; Virgili, Anna C AC; Menso, María M MM; Martín-Broto, Javier J; Sansó, Miriam M; García-Valverde, Alfonso A; Rosell, Jordi J; Fletcher, Jonathan A JA; George, Suzanne S; Carles, Joan J; Arribas, Joaquín J
Publication Date: 2020-02-05

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 32024476
Variant Present in the following documents:
  • Main text
  • 12885_2020_Article_6597.pdf
View BVdb publication page



HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.

The Journal Of Pathology. Clinical Research
Angelika Ihle, Michaela M; Merkelbach-Bruse, Sabine S; Hartmann, Wolfgang W; Bauer, Sebastian S; Ratner, Nancy N; Sonobe, Hiroshi H; Nishio, Jun J; Larsson, Olle O; Åman, Pierre P; Pedeutour, Florence F; Taguchi, Takahiro T; Wardelmann, Eva E; Buettner, Reinhard R; Schildhaus, Hans-Ulrich HU
Publication Date: 2016-04

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 27499916
Variant Present in the following documents:
  • Main text
  • CJP2-2-059.pdf
View BVdb publication page



miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours.

Molecular Oncology
Ihle, Michaela Angelika MA; Trautmann, Marcel M; Kuenstlinger, Helen H; Huss, Sebastian S; Heydt, Carina C; Fassunke, Jana J; Wardelmann, Eva E; Bauer, Sebastian S; Schildhaus, Hans-Ulrich HU; Buettner, Reinhard R; Merkelbach-Bruse, Sabine S
Publication Date: 2015-08

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 25898773
Variant Present in the following documents:
  • Main text
View BVdb publication page



The HSP90 inhibitor, AT13387, is effective against imatinib-sensitive and -resistant gastrointestinal stromal tumor models.

Molecular Cancer Therapeutics
Smyth, Tomoko T; Van Looy, Thomas T; Curry, Jayne E JE; Rodriguez-Lopez, Ana M AM; Wozniak, Agnieszka A; Zhu, Meijun M; Donsky, Rachel R; Morgan, Jennifer G JG; Mayeda, Mark M; Fletcher, Jonathan A JA; Schöffski, Patrick P; Lyons, John J; Thompson, Neil T NT; Wallis, Nicola G NG
Publication Date: 2012-08

Variant appearance in text: KIT: V560_Y578del
PubMed Link: 22714264
Variant Present in the following documents:
  • Main text
View BVdb publication page