Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.
Nature Genetics
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Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Evaluation of the role of STAP1 in Familial Hypercholesterolemia.
Scientific Reports
Danyel, Magdalena M; Ott, Claus-Eric CE; Grenkowitz, Thomas T; Salewsky, Bastian B; Hicks, Andrew A AA; Fuchsberger, Christian C; Steinhagen-Thiessen, Elisabeth E; Bobbert, Thomas T; Kassner, Ursula U; Demuth, Ilja I
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.
Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
Plos Genetics
Byars, Sean G SG; Huang, Qin Qin QQ; Gray, Lesley-Ann LA; Bakshi, Andrew A; Ripatti, Samuli S; Abraham, Gad G; Stearns, Stephen C SC; Inouye, Michael M
Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells.
Elife
Hogan, Nicholas T NT; Whalen, Michael B MB; Stolze, Lindsey K LK; Hadeli, Nizar K NK; Lam, Michael T MT; Springstead, James R JR; Glass, Christopher K CK; Romanoski, Casey E CE
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.
Genome Biology
Joehanes, Roby R; Zhang, Xiaoling X; Huan, Tianxiao T; Yao, Chen C; Ying, Sai-Xia SX; Nguyen, Quang Tri QT; Demirkale, Cumhur Yusuf CY; Feolo, Michael L ML; Sharopova, Nataliya R NR; Sturcke, Anne A; Schäffer, Alejandro A AA; Heard-Costa, Nancy N; Chen, Han H; Liu, Po-Ching PC; Wang, Richard R; Woodhouse, Kimberly A KA; Tanriverdi, Kahraman K; Freedman, Jane E JE; Raghavachari, Nalini N; Dupuis, Josée J; Johnson, Andrew D AD; O'Donnell, Christopher J CJ; Levy, Daniel D; Munson, Peter J PJ
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Nature Genetics
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Arteriosclerosis, Thrombosis, And Vascular Biology
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Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
Plos Genetics
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