Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.
Nature Genetics
Zhou, Xueya X; Feliciano, Pamela P; Shu, Chang C; Wang, Tianyun T; Astrovskaya, Irina I; Hall, Jacob B JB; Obiajulu, Joseph U JU; Wright, Jessica R JR; Murali, Shwetha C SC; Xu, Simon Xuming SX; Brueggeman, Leo L; Thomas, Taylor R TR; Marchenko, Olena O; Fleisch, Christopher C; Barns, Sarah D SD; Snyder, LeeAnne Green LG; Han, Bing B; Chang, Timothy S TS; Turner, Tychele N TN; Harvey, William T WT; Nishida, Andrew A; O'Roak, Brian J BJ; Geschwind, Daniel H DH; , ; Michaelson, Jacob J JJ; Volfovsky, Natalia N; Eichler, Evan E EE; Shen, Yufeng Y; Chung, Wendy K WK
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
Nature Genetics
Dulak, Austin M AM; Stojanov, Petar P; Peng, Shouyong S; Lawrence, Michael S MS; Fox, Cameron C; Stewart, Chip C; Bandla, Santhoshi S; Imamura, Yu Y; Schumacher, Steven E SE; Shefler, Erica E; McKenna, Aaron A; Carter, Scott L SL; Cibulskis, Kristian K; Sivachenko, Andrey A; Saksena, Gordon G; Voet, Douglas D; Ramos, Alex H AH; Auclair, Daniel D; Thompson, Kristin K; Sougnez, Carrie C; Onofrio, Robert C RC; Guiducci, Candace C; Beroukhim, Rameen R; Zhou, Zhongren Z; Lin, Lin L; Lin, Jules J; Reddy, Rishindra R; Chang, Andrew A; Landrenau, Rodney R; Pennathur, Arjun A; Ogino, Shuji S; Luketich, James D JD; Golub, Todd R TR; Gabriel, Stacey B SB; Lander, Eric S ES; Beer, David G DG; Godfrey, Tony E TE; Getz, Gad G; Bass, Adam J AJ
Functional roles of the pre-sensor I insertion sequence in an AAA+ bacterial enhancer binding protein.
Molecular Microbiology
Burrows, Patricia C PC; Schumacher, Jörg J; Amartey, Samuel S; Ghosh, Tamaswati T; Burgis, Timothy A TA; Zhang, Xiaodong X; Nixon, B Tracy BT; Buck, Martin M
Coupling sigma factor conformation to RNA polymerase reorganisation for DNA melting.
Journal Of Molecular Biology
Burrows, Patricia C PC; Joly, Nicolas N; Cannon, Wendy V WV; Cámara, Beatriz P BP; Rappas, Mathieu M; Zhang, Xiaodong X; Dawes, Kathleen K; Nixon, B Tracy BT; Wigneshweraraj, Siva R SR; Buck, Martin M
Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action.
Genes & Development
Chaney, M M; Grande, R R; Wigneshweraraj, S R SR; Cannon, W W; Casaz, P P; Gallegos, M T MT; Schumacher, J J; Jones, S S; Elderkin, S S; Dago, A E AE; Morett, E E; Buck, M M