Publications:

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HaploCoV: unsupervised classification and rapid detection of novel emerging variants of SARS-CoV-2.

Communications Biology

Chiara, Matteo M; Horner, David S DS; Ferrandi, Erika E; Gissi, Carmela C; Pesole, Graziano G

Publication Date: 2023-04-22

Variant appearance in text: GC: 203T>C; V68A

PubMed Link: 37087497

Variant Present in the following documents:

• 42003_2023_4784_MOESM4_ESM.xlsx, sheet 1

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Rickettsia felis DNA recovered from a child who lived in southern Africa 2000 years ago.

Communications Biology

Rifkin, Riaan F RF; Vikram, Surendra S; Alcorta, Jaime J; Ramond, Jean-Baptiste JB; Cowan, Don A DA; Jakobsson, Mattias M; Schlebusch, Carina M CM; Lombard, Marlize M

Publication Date: 2023-03-03

Variant appearance in text: GC: 203T>C

PubMed Link: 36869137

Variant Present in the following documents:

• 42003_2023_4582_MOESM4_ESM.xlsx, sheet 10
• 42003_2023_4582_MOESM4_ESM.xlsx, sheet 9

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Enantioselective Single and Dual α-C-H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer.

Journal Of The American Chemical Society

Ren, Xinkun X; Couture, Bo M BM; Liu, Ningyu N; Lall, Manjinder S MS; Kohrt, Jeffrey T JT; Fasan, Rudi R

Publication Date: 2022-12-21

Variant appearance in text: GC: V68A

PubMed Link: 36542059

Variant Present in the following documents:

• Main text
• ja2c10775_si_001.pdf
• ja2c10775.pdf

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Endothelial alpha globin is a nitrite reductase.

Nature Communications

Keller, T C Stevenson TCS; Lechauve, Christophe C; Keller, Alexander S AS; Broseghini-Filho, Gilson Brás GB; Butcher, Joshua T JT; Askew Page, Henry R HR; Islam, Aditi A; Tan, Zhe Yin ZY; DeLalio, Leon J LJ; Brooks, Steven S; Sharma, Poonam P; Hong, Kwangseok K; Xu, Wenhao W; Padilha, Alessandra Simão AS; Ruddiman, Claire A CA; Best, Angela K AK; Macal, Edgar E; Kim-Shapiro, Daniel B DB; Christ, George G; Yan, Zhen Z; Cortese-Krott, Miriam M MM; Ricart, Karina K; Patel, Rakesh R; Bender, Timothy P TP; Sonkusare, Swapnil K SK; Weiss, Mitchell J MJ; Ackerman, Hans H; Columbus, Linda L; Isakson, Brant E BE

Publication Date: 2022-10-27

Variant appearance in text: GC: 203T>C

PubMed Link: 36302779

Variant Present in the following documents:

• 41467_2022_34154_MOESM3_ESM.xlsx, sheet 10
• 41467_2022_34154_MOESM3_ESM.xlsx, sheet 11

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Highly stereoselective and enantiodivergent synthesis of cyclopropylphosphonates with engineered carbene transferases.

Chemical Science

Ren, Xinkun X; Chandgude, Ajay L AL; Carminati, Daniela M DM; Shen, Zhuofan Z; Khare, Sagar D SD; Fasan, Rudi R

Publication Date: 2022-07-29

Variant appearance in text: GC: V68A

PubMed Link: 35974764

Variant Present in the following documents:

• Main text
• SC-013-D2SC01965E.pdf
• SC-013-D2SC01965E-s001.pdf

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: GC: 203T>C

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

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Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization.

Biochemistry

Iannuzzelli, Jacob A JA; Bacik, John-Paul JP; Moore, Eric J EJ; Shen, Zhuofan Z; Irving, Ellen M EM; Vargas, David A DA; Khare, Sagar D SD; Ando, Nozomi N; Fasan, Rudi R

Publication Date: 2022-05-25

Variant appearance in text: GC: V68A

PubMed Link: 35612958

Variant Present in the following documents:

• Main text
• bi2c00033.pdf

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K-Ras-Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated.

Molecules And Cells

Lee, You-Soub YS; Lee, Ja-Yeol JY; Song, Soo-Hyun SH; Kim, Da-Mi DM; Lee, Jung-Won JW; Chi, Xin-Zi XZ; Ito, Yoshiaki Y; Bae, Suk-Chul SC

Publication Date: 2020-10-31

Variant appearance in text: GC: 203T>C; Val68Ala

PubMed Link: 33115981

Variant Present in the following documents:

• molce-43-889_Supple.xlsx, sheet 1

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An Enzymatic Platform for the Highly Enantioselective and Stereodivergent Construction of Cyclopropyl-δ-lactones.

Angewandte Chemie (International Ed. In English)

Ren, Xinkun X; Liu, Ningyu N; Chandgude, Ajay L AL; Fasan, Rudi R

Publication Date: 2020-11-23

Variant appearance in text: GC: V68A

PubMed Link: 32667122

Variant Present in the following documents:

• Main text

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Highly Stereoselective Synthesis of Fused Cyclopropane-γ-Lactams via Biocatalytic Iron-Catalyzed Intramolecular Cyclopropanation.

Acs Catalysis

Ren, Xinkun X; Chandgude, Ajay L AL; Fasan, Rudi R

Publication Date: 2020-02-07

Variant appearance in text: GC: V68A

PubMed Link: 32257580

Variant Present in the following documents:

• Main text

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Selective Functionalization of Aliphatic Amines via Myoglobin-catalyzed Carbene N-H Insertion.

Synlett : Accounts And Rapid Communications In Synthetic Organic Chemistry

Steck, Viktoria V; Sreenilayam, Gopeekrishnan G; Fasan, Rudi R

Publication Date: 2020-02

Variant appearance in text: GC: V68A

PubMed Link: 32255925

Variant Present in the following documents:

• Main text

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Semi-Rationally Designed Short Peptides Self-Assemble and Bind Hemin to Promote Cyclopropanation.

Angewandte Chemie (International Ed. In English)

Zozulia, Oleksii O; Korendovych, Ivan V IV

Publication Date: 2020-05-18

Variant appearance in text: GC: V68A

PubMed Link: 32128962

Variant Present in the following documents:

• Main text

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Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe.

G3 (Bethesda, Md.)

Hoyos-Manchado, Rafael R; Villa-Consuegra, Sergio S; Berraquero, Modesto M; Jiménez, Juan J; Tallada, Víctor A VA

Publication Date: 2020-03-05

Variant appearance in text: GC: Val68Ala

PubMed Link: 31900332

Variant Present in the following documents:

• Main text
• 917.pdf

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Origin of high stereocontrol in olefin cyclopropanation catalyzed by an engineered carbene transferase.

Acs Catalysis

Tinoco, Antonio A; Wei, Yang Y; Bacik, John-Paul JP; Carminati, Daniela M DM; Moore, Eric J EJ; Ando, Nozomi N; Zhang, Yong Y; Fasan, Rudi R

Publication Date: 2019-02-01

Variant appearance in text: GC: V68A

PubMed Link: 31134138

Variant Present in the following documents:

• Main text

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Biocatalytic Strategy for Highly Diastereo- and Enantioselective Synthesis of 2,3-Dihydrobenzofuran-Based Tricyclic Scaffolds.

Angewandte Chemie (International Ed. In English)

Vargas, David A DA; Khade, Rahul L RL; Zhang, Yong Y; Fasan, Rudi R

Publication Date: 2019-07-22

Variant appearance in text: GC: V68A

PubMed Link: 31099936

Variant Present in the following documents:

• Main text

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Stereodivergent Intramolecular Cyclopropanation Enabled by Engineered Carbene Transferases.

Journal Of The American Chemical Society

Chandgude, Ajay L AL; Ren, Xinkun X; Fasan, Rudi R

Publication Date: 2019-06-12

Variant appearance in text: GC: V68A

PubMed Link: 31099569

Variant Present in the following documents:

• Main text

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Human gastric cancer modelling using organoids.

Gut

Seidlitz, Therese T; Merker, Sebastian R SR; Rothe, Alexander A; Zakrzewski, Falk F; von Neubeck, Cläre C; Grützmann, Konrad K; Sommer, Ulrich U; Schweitzer, Christine C; Schölch, Sebastian S; Uhlemann, Heike H; Gaebler, Anne-Marlene AM; Werner, Kristin K; Krause, Mechthild M; Baretton, Gustavo B GB; Welsch, Thilo T; Koo, Bon-Kyoung BK; Aust, Daniela E DE; Klink, Barbara B; Weitz, Jürgen J; Stange, Daniel E DE

Publication Date: 2019-02

Variant appearance in text: GC: Val68Ala

PubMed Link: 29703791

Variant Present in the following documents:

• gutjnl-2017-314549supp010.xlsx, sheet 3

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Metal Substitution Modulates the Reactivity and Extends the Reaction Scope of Myoglobin Carbene Transfer Catalysts.

Advanced Synthesis & Catalysis

Sreenilayam, Gopeekrishnan G; Moore, Eric J EJ; Steck, Viktoria V; Fasan, Rudi R

Publication Date: 2017-06-19

Variant appearance in text: GC: V68A

PubMed Link: 29606929

Variant Present in the following documents:

• Main text

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Comparative analysis of primary versus relapse/refractory DLBCL identifies shifts in mutation spectrum.

Oncotarget

Greenawalt, Danielle M DM; Liang, Winnie S WS; Saif, Sakina S; Johnson, Justin J; Todorov, Petar P; Dulak, Austin A; Enriquez, Daniel D; Halperin, Rebecca R; Ahmed, Ambar A; Saveliev, Vladislav V; Carpten, John J; Craig, David D; Barrett, J Carl JC; Dougherty, Brian B; Zinda, Michael M; Fawell, Stephen S; Dry, Jonathan R JR; Byth, Kate K

Publication Date: 2017-11-21

Variant appearance in text: GC: 203T>C

PubMed Link: 29245897

Variant Present in the following documents:

• oncotarget-08-99237-s002.xlsx, sheet 1

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Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene.

Journal Of The American Chemical Society

Tinoco, Antonio A; Steck, Viktoria V; Tyagi, Vikas V; Fasan, Rudi R

Publication Date: 2017-04-19

Variant appearance in text: GC: V68A

PubMed Link: 28366001

Variant Present in the following documents:

• Main text

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Variant discovery in the sheep milk transcriptome using RNA sequencing.

Bmc Genomics

Suárez-Vega, Aroa A; Gutiérrez-Gil, Beatriz B; Klopp, Christophe C; Tosser-Klopp, Gwenola G; Arranz, Juan José JJ

Publication Date: 2017-02-15

Variant appearance in text: GC: 203T>C

PubMed Link: 28202015

Variant Present in the following documents:

• 12864_2017_3581_MOESM1_ESM.xlsx, sheet 1

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Gram-Scale Synthesis of Chiral Cyclopropane-Containing Drugs and Drug Precursors with Engineered Myoglobin Catalysts Featuring Complementary Stereoselectivity.

Angewandte Chemie (International Ed. In English)

Bajaj, Priyanka P; Sreenilayam, Gopeekrishnan G; Tyagi, Vikas V; Fasan, Rudi R

Publication Date: 2016-12-23

Variant appearance in text: GC: V68A

PubMed Link: 27885768

Variant Present in the following documents:

• Main text

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Efficient conversion of primary azides to aldehydes catalyzed by active site variants of myoglobin.

Chemical Science

Giovani, Simone S; Singh, Ritesh R; Fasan, Rudi R

Publication Date: 2016

Variant appearance in text: GC: V68A

PubMed Link: 26900445

Variant Present in the following documents:

• Main text
• SC-007-C5SC02857D.pdf

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Myoglobin-Catalyzed Olefination of Aldehydes.

Angewandte Chemie (International Ed. In English)

Tyagi, Vikas V; Fasan, Rudi R

Publication Date: 2016-02-12

Variant appearance in text: GC: V68A

PubMed Link: 26765247

Variant Present in the following documents:

• Main text

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Intermolecular carbene S-H insertion catalysed by engineered myoglobin-based catalysts†.

Chemical Science

Tyagi, Vikas V; Bonn, Rachel B RB; Fasan, Rudi R

Publication Date: 2015-04-01

Variant appearance in text: GC: V68A

PubMed Link: 26101581

Variant Present in the following documents:

• Main text
• SC-006-C5SC00080G.pdf

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Highly diastereoselective and enantioselective olefin cyclopropanation using engineered myoglobin-based catalysts.

Angewandte Chemie (International Ed. In English)

Bordeaux, Melanie M; Tyagi, Vikas V; Fasan, Rudi R

Publication Date: 2015-02-02

Variant appearance in text: GC: V68A

PubMed Link: 25538035

Variant Present in the following documents:

• Main text

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The genetic landscape of high-risk neuroblastoma.

Nature Genetics

Pugh, Trevor J TJ; Morozova, Olena O; Attiyeh, Edward F EF; Asgharzadeh, Shahab S; Wei, Jun S JS; Auclair, Daniel D; Carter, Scott L SL; Cibulskis, Kristian K; Hanna, Megan M; Kiezun, Adam A; Kim, Jaegil J; Lawrence, Michael S MS; Lichenstein, Lee L; McKenna, Aaron A; Pedamallu, Chandra Sekhar CS; Ramos, Alex H AH; Shefler, Erica E; Sivachenko, Andrey A; Sougnez, Carrie C; Stewart, Chip C; Ally, Adrian A; Birol, Inanc I; Chiu, Readman R; Corbett, Richard D RD; Hirst, Martin M; Jackman, Shaun D SD; Kamoh, Baljit B; Khodabakshi, Alireza Hadj AH; Krzywinski, Martin M; Lo, Allan A; Moore, Richard A RA; Mungall, Karen L KL; Qian, Jenny J; Tam, Angela A; Thiessen, Nina N; Zhao, Yongjun Y; Cole, Kristina A KA; Diamond, Maura M; Diskin, Sharon J SJ; Mosse, Yael P YP; Wood, Andrew C AC; Ji, Lingyun L; Sposto, Richard R; Badgett, Thomas T; London, Wendy B WB; Moyer, Yvonne Y; Gastier-Foster, Julie M JM; Smith, Malcolm A MA; Guidry Auvil, Jaime M JM; Gerhard, Daniela S DS; Hogarty, Michael D MD; Jones, Steven J M SJ; Lander, Eric S ES; Gabriel, Stacey B SB; Getz, Gad G; Seeger, Robert C RC; Khan, Javed J; Marra, Marco A MA; Meyerson, Matthew M; Maris, John M JM

Publication Date: 2013-03

Variant appearance in text: GC: 203T>C; V68A

PubMed Link: 23334666

Variant Present in the following documents:

• NIHMS474900-supplement-3.xlsx, sheet 1

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