Publications:

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Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.

Nature Genetics

Schlosser, Pascal P; Scherer, Nora N; Grundner-Culemann, Franziska F; Monteiro-Martins, Sara S; Haug, Stefan S; Steinbrenner, Inga I; Uluvar, Burulça B; Wuttke, Matthias M; Cheng, Yurong Y; Ekici, Arif B AB; Gyimesi, Gergely G; Karoly, Edward D ED; Kotsis, Fruzsina F; Mielke, Johanna J; Gomez, Maria F MF; Yu, Bing B; Grams, Morgan E ME; Coresh, Josef J; Boerwinkle, Eric E; Köttgen, Michael M; Kronenberg, Florian F; Meiselbach, Heike H; Mohney, Robert P RP; Akilesh, Shreeram S; , ; Schmidts, Miriam M; Hediger, Matthias A MA; Schultheiss, Ulla T UT; Eckardt, Kai-Uwe KU; Oefner, Peter J PJ; Sekula, Peggy P; Li, Yong Y; Köttgen, Anna A

Publication Date: 2023-06-05

Variant appearance in text: ABCG2: 421C>A; Gln141Lys; rs2231142

PubMed Link: 37277652

Variant Present in the following documents:

• Main text
• 41588_2023_1409_MOESM4_ESM.pdf
• 41588_2023_1409_MOESM6_ESM.xlsx, sheet 17
• 41588_2023_Article_1409.pdf
• 41588_2023_1409_MOESM5_ESM.pdf

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Genetic polymorphisms influencing deferasirox pharmacokinetics, efficacy, and adverse drug reactions: a systematic review and meta-analysis.

Frontiers In Pharmacology

Yampayon, Kittika K; Anantachoti, Puree P; Chongmelaxme, Bunchai B; Yodsurang, Varalee V

Publication Date: 2023

Variant appearance in text: rs2231142

PubMed Link: 37261288

Variant Present in the following documents:

• Main text
• DataSheet1.pdf
• fphar-14-1069854.pdf

View BVdb publication page

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Impact of Hyper- and Hypo-Uricemia on Kidney Function.

Biomedicines

Miake, Junichiro J; Hisatome, Ichiro I; Tomita, Katsuyuki K; Isoyama, Tadahiro T; Sugihara, Shinobu S; Kuwabara, Masanari M; Ogino, Kazuhide K; Ninomiya, Haruaki H

Publication Date: 2023-04-24

Variant appearance in text: ABCG2: Q141K

PubMed Link: 37238929

Variant Present in the following documents:

• Main text
• biomedicines-11-01258.pdf

View BVdb publication page

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Case report: Hepatotoxicity and nephrotoxicity induced by methotrexate in a paediatric patient, what is the role of precision medicine in 2023?

Frontiers In Pharmacology

El Masri, Ali El Rida AER; Tobler, Caroline C; Willemijn, Breunis B; Von Bueren, Andre O AO; Ansari, Marc M; Samer, Caroline Flora CF

Publication Date: 2023

Variant appearance in text: ABCG2: 421C>A; rs2231142

PubMed Link: 37201023

Variant Present in the following documents:

• Main text
• fphar-14-1130548.pdf

View BVdb publication page

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Cannabis Pharmacogenomics: A Path to Personalized Medicine.

Current Issues In Molecular Biology

Babayeva, Mariana M; Loewy, Zvi G ZG

Publication Date: 2023-04-17

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 37185752

Variant Present in the following documents:

• Main text
• cimb-45-00228.pdf

View BVdb publication page

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A nomogram based on genotypic and clinicopathologic factors to predict the non-sentinel lymph node metastasis in Chinese women breast cancer patients.

Frontiers In Oncology

Zhu, Liling L; Liu, Ke K; Bao, Baoshi B; Li, Fengyun F; Liang, Wentao W; Jiang, Zhaoyun Z; Hao, Xiaopeng X; Wang, Jiandong J

Publication Date: 2023

Variant appearance in text: rs2231142

PubMed Link: 37152050

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

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Laboratory Findings of Benign Convulsions With Mild Gastroenteritis: A Meta-Analysis.

Cureus

Miyagi, Yoshifumi Y; Sasano, Tomoyuki T; Kin, Kentoku K

Publication Date: 2023-03

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 37123782

Variant Present in the following documents:

• Main text
• cureus-0015-00000036784.pdf

View BVdb publication page

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A Comprehensive Analysis of 21 Actionable Pharmacogenes in the Spanish Population: From Genetic Characterisation to Clinical Impact.

Pharmaceutics

Nunez-Torres, Rocio R; Pita, Guillermo G; Peña-Chilet, María M; López-López, Daniel D; Zamora, Jorge J; Roldán, Gema G; Herráez, Belén B; Álvarez, Nuria N; Alonso, María Rosario MR; Dopazo, Joaquín J; Gonzalez-Neira, Anna A

Publication Date: 2023-04-19

Variant appearance in text: rs2231142

PubMed Link: 37111771

Variant Present in the following documents:

• Main text
• pharmaceutics-15-01286.pdf

View BVdb publication page

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ABCG2 in Acute Myeloid Leukemia: Old and New Perspectives.

International Journal Of Molecular Sciences

Damiani, Daniela D; Tiribelli, Mario M

Publication Date: 2023-04-12

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 37108308

Variant Present in the following documents:

• Main text
• ijms-24-07147.pdf

View BVdb publication page

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Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans.

Pharmacogenetics And Genomics

Mateza, Somila S; Bradford, Yuki Y; Maartens, Gary G; Sokhela, Simiso S; Chandiwana, Nomathemba C NC; Venter, Willem D F WDF; Post, Frank A FA; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P

Publication Date: 2023-04-24

Variant appearance in text: rs2231142

PubMed Link: 37099271

Variant Present in the following documents:

• Main text
• pgen-33-91.pdf

View BVdb publication page

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A meta-analysis and experimental data for multidrug resistance genes in breast cancer.

African Health Sciences

Zaib, Shumaila S; Tahir, Sammia S; Masood, Nosheen N; Hameed, Abdul A; Azra, Yasmin Y

Publication Date: 2022-12

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 37092084

Variant Present in the following documents:

• AFHS2204-0001.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: ABCG2: Q141K

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3

View BVdb publication page

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Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance.

Clinical Pharmacokinetics

Hovd, Markus M; Robertsen, Ida I; Johnson, Line Kristin LK; Krogstad, Veronica V; Wegler, Christine C; Kvitne, Kine Eide KE; Kringen, Marianne Kristiansen MK; Skovlund, Eva E; Karlsson, Cecilia C; Andersson, Shalini S; Artursson, Per P; Sandbu, Rune R; Hjelmesæth, Jøran J; Åsberg, Anders A; Jansson-Löfmark, Rasmus R; Christensen, Hege H

Publication Date: 2023-03-29

Variant appearance in text: BCRP: Q141K

PubMed Link: 36988826

Variant Present in the following documents:

• Main text
• 40262_2023_Article_1235.pdf
• 40262_2023_1235_MOESM1_ESM.pdf

View BVdb publication page

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Pilot Study on the Impact of Polymorphisms Linked to Multi-Kinase Inhibitor Metabolism on Lenvatinib Side Effects in Patients with Advanced Thyroid Cancer.

International Journal Of Molecular Sciences

Cantara, Silvia S; Dalmiglio, Cristina C; Marzocchi, Carlotta C; Sagnella, Alfonso A; Brilli, Lucia L; Trimarchi, Andrea A; Maino, Fabio F; Valerio, Laura L; Castagna, Maria Grazia MG

Publication Date: 2023-03-13

Variant appearance in text: rs2231142

PubMed Link: 36982571

Variant Present in the following documents:

• Main text

View BVdb publication page

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The ABCG2 rs2231142 polymorphism and the risk of nephrolithiasis: A case-control study from the Taiwan biobank.

Frontiers In Endocrinology

Lin, Ching-Tsai CT; Chen, I-Chieh IC; Chen, Yen-Ju YJ; Lin, Ying-Cheng YC; Chang, Jui-Chun JC; Wang, Tsai-Jung TJ; Huang, Wen-Nan WN; Chen, Yi-Hsing YH; Chen, Yi-Huei YH; Lin, Ching-Heng CH; Chen, Yi-Ming YM

Publication Date: 2023

Variant appearance in text: rs2231142

PubMed Link: 36967798

Variant Present in the following documents:

• Main text
• fendo-14-1074012.pdf

View BVdb publication page

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Integrative proteogenomic characterization of early esophageal cancer.

Nature Communications

Li, Lingling L; Jiang, Dongxian D; Zhang, Qiao Q; Liu, Hui H; Xu, Fujiang F; Guo, Chunmei C; Qin, Zhaoyu Z; Wang, Haixing H; Feng, Jinwen J; Liu, Yang Y; Chen, Weijie W; Zhang, Xue X; Bai, Lin L; Tian, Sha S; Tan, Subei S; Xu, Chen C; Song, Qi Q; Liu, Yalan Y; Zhong, Yunshi Y; Chen, Tianyin T; Zhou, Pinghong P; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C

Publication Date: 2023-03-25

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 36966136

Variant Present in the following documents:

• 41467_2023_37440_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Personalized Dose of Adjuvant Imatinib in Patients with Gastrointestinal Stromal Tumors: Results from a Population Pharmacokinetic Analysis.

Drug Design, Development And Therapy

Jiang, Xuehui X; Fu, Qun Q; Jing, Yan Y; Kong, Ying Y; Liu, Hong H; Peng, Hongwei H; Rexiti, Kaisaner K; Wei, Xiaohua X

Publication Date: 2023

Variant appearance in text: rs2231142

PubMed Link: 36942304

Variant Present in the following documents:

• Main text
• dddt-17-809.pdf

View BVdb publication page

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Hmong microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C): A phase II clinical study protocol.

Plos One

Wen, Ya-Feng YF; Culhane-Pera, Kathleen A KA; Pergament, Shannon L SL; Moua, Yeng Y; Vue, Bai B; Yang, Toua T; Lo, Muaj M; Sun, Boguang B; Knights, Dan D; Straka, Robert J RJ

Publication Date: 2023

Variant appearance in text: rs2231142

PubMed Link: 36724193

Variant Present in the following documents:

• pone.0279830.s002.pdf

View BVdb publication page

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Pharmacogenomic variabilities in geo-ancestral subpopulations and their clinical implications: Results of collaborations with Hmong in the United States.

Frontiers In Genetics

Sun, Boguang B; Wen, Ya-Feng YF; Culhane-Pera, Kathleen A KA; Lo, Muaj M; Straka, Robert J RJ

Publication Date: 2022

Variant appearance in text: rs2231142

PubMed Link: 36685861

Variant Present in the following documents:

• Main text
• fgene-13-1070236.pdf

View BVdb publication page

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Antiretroviral Levels in the Cerebrospinal Fluid: The Effect of Inflammation and Genetic Variants.

Diagnostics (Basel, Switzerland)

Cusato, Jessica J; Avataneo, Valeria V; Antonucci, Miriam M; Trunfio, Mattia M; Marinaro, Letizia L; Palermiti, Alice A; Manca, Alessandra A; Di Perri, Giovanni G; Mula, Jacopo J; Bonora, Stefano S; D'Avolio, Antonio A; Calcagno, Andrea A

Publication Date: 2023-01-12

Variant appearance in text: rs2231142

PubMed Link: 36673105

Variant Present in the following documents:

• Main text
• diagnostics-13-00295.pdf

View BVdb publication page

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Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine

Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA

Publication Date: 2023-01-17

Variant appearance in text: ABCG2: Q141K

PubMed Link: 36652909

Variant Present in the following documents:

• mmc3.xlsx, sheet 32

View BVdb publication page

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Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients.

Scientific Reports

Ohashi, Yuki Y; Toyoda, Masao M; Saito, Nobumichi N; Koizumi, Masahiro M; Kanai, Genta G; Komaba, Hirotaka H; Kimura, Moritsugu M; Wada, Takehiko T; Takahashi, Hiroo H; Takahashi, Yuichiro Y; Ishida, Naoto N; Kakuta, Takatoshi T; Fukagawa, Masafumi M; Ichida, Kimiyoshi K

Publication Date: 2023-01-13

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 36639673

Variant Present in the following documents:

• Main text
• 41598_2022_Article_26519.pdf
• 41598_2022_26519_MOESM1_ESM.pdf

View BVdb publication page

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Population Pharmacokinetics, Pharmacogenomics, and Adverse Events of Osimertinib and its Two Active Metabolites, AZ5104 and AZ7550, in Japanese Patients with Advanced Non-small Cell Lung Cancer: a Prospective Observational Study.

Investigational New Drugs

Ishikawa, Emi E; Yokoyama, Yuta Y; Chishima, Haruna H; Kasai, Hidefumi H; Kuniyoshi, Ouki O; Kimura, Motonori M; Hakamata, Jun J; Nakada, Hideo H; Suehiro, Naoya N; Nakaya, Naoki N; Nakajima, Hideo H; Ikemura, Shinnosuke S; Kawada, Ichiro I; Yasuda, Hiroyuki H; Terai, Hideki H; Jibiki, Aya A; Kawazoe, Hitoshi H; Soejima, Kenzo K; Muramatsu, Hiroshi H; Suzuki, Sayo S; Nakamura, Tomonori T

Publication Date: 2023-01-13

Variant appearance in text: rs2231142

PubMed Link: 36637703

Variant Present in the following documents:

• Main text
• 10637_2023_Article_1328.pdf

View BVdb publication page

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Gene polymorphisms and prognosis of head and neck squamous cell carcinoma: a systematic review.

Reports Of Practical Oncology And Radiotherapy : Journal Of Greatpoland Cancer Center In Poznan And Polish Society Of Radiation Oncology

Rajabi-Moghaddam, Mahdieh M; Abbaszadeh, Hamid H

Publication Date: 2022

Variant appearance in text: rs2231142

PubMed Link: 36632296

Variant Present in the following documents:

• rpor-27-6-1045.pdf

View BVdb publication page

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Should we test for SLCO1B1 genotype before prescribing statins?-a discussion of clinical trial results.

Annals Of Translational Medicine

Zhou, Yitian Y; Lauschke, Volker M VM

Publication Date: 2022-12

Variant appearance in text: rs2231142

PubMed Link: 36618803

Variant Present in the following documents:

• Main text
• atm-10-23-1293.pdf

View BVdb publication page

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Assessment of causal associations between uric acid and 25-hydroxyvitamin D levels.

Frontiers In Endocrinology

Han, Yingdong Y; Zhang, Yun Y; Zeng, Xuejun X

Publication Date: 2022

Variant appearance in text: rs2231142

PubMed Link: 36583002

Variant Present in the following documents:

• Main text
• fendo-13-1024675.pdf

View BVdb publication page

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Circulating messenger RNA variants as a potential biomarker for surveillance of hepatocellular carcinoma.

Frontiers In Oncology

Block, Timothy T; Zezulinski, Daniel D; Kaplan, David E DE; Lu, Jingqiao J; Zanine, Samantha S; Zhan, Tingting T; Doria, Cataldo C; Sayeed, Aejaz A

Publication Date: 2022

Variant appearance in text: rs2231142

PubMed Link: 36582804

Variant Present in the following documents:

• Table_6.xlsx, sheet 1

View BVdb publication page

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A Pan-Cancer Landscape of ABCG2 across Human Cancers: Friend or Foe?

International Journal Of Molecular Sciences

Lyu, Chen C; Wang, Lili L; Stadlbauer, Birgit B; Buchner, Alexander A; Pohla, Heike H

Publication Date: 2022-12-15

Variant appearance in text: ABCG2: Q141K

PubMed Link: 36555598

Variant Present in the following documents:

• Main text
• ijms-23-15955.pdf

View BVdb publication page

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Hyperuricemia and Endothelial Function: Is It a Simple Association or Do Gender Differences Play a Role in This Binomial?

Biomedicines

Ciarambino, Tiziana T; Crispino, Pietro P; Giordano, Mauro M

Publication Date: 2022-11-29

Variant appearance in text: ABCG2: Q141K

PubMed Link: 36551823

Variant Present in the following documents:

• biomedicines-10-03067.pdf

View BVdb publication page

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Pharmacogenetics of chemotherapy treatment response and -toxicities in patients with osteosarcoma: a systematic review.

Bmc Cancer

Hurkmans, Evelien G E EGE; Brand, Annouk C A M ACAM; Verdonschot, Job A J JAJ; Te Loo, D Maroeska W M DMWM; Coenen, Marieke J H MJH

Publication Date: 2022-12-19

Variant appearance in text: rs2231142

PubMed Link: 36536332

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10434.pdf

View BVdb publication page

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Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia.

Frontiers In Pharmacology

Xu, Meng M; Wu, Shuangshuang S; Wang, Yue Y; Zhao, Yundong Y; Wang, Ximin X; Wei, Changhong C; Liu, Xueying X; Hao, Feng F; Hu, Cheng C

Publication Date: 2022

Variant appearance in text: rs2231142

PubMed Link: 36532750

Variant Present in the following documents:

• Main text
• fphar-13-1003812.pdf

View BVdb publication page

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New insight into the management of renal excretion and hyperuricemia: Potential therapeutic strategies with natural bioactive compounds.

Frontiers In Pharmacology

Yang, Bendong B; Xin, Meiling M; Liang, Shufei S; Xu, Xiaoxue X; Cai, Tianqi T; Dong, Ling L; Wang, Chao C; Wang, Meng M; Cui, Yuting Y; Song, Xinhua X; Sun, Jinyue J; Sun, Wenlong W

Publication Date: 2022

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 36483739

Variant Present in the following documents:

• Main text
• fphar-13-1026246.pdf

View BVdb publication page

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Genetic variations in relation to bleeding and pharmacodynamics of dabigatran in Chinese patients with nonvalvular atrial fibrillation: A nationwide multicentre prospective cohort study.

Clinical And Translational Medicine

Xiang, Qian Q; Xie, Qiufen Q; Liu, Zhiyan Z; Mu, Guangyan G; Zhang, Hanxu H; Zhou, Shuang S; Wang, Zhe Z; Wang, Zining Z; Zhang, Yatong Y; Zhao, Zinan Z; Yuan, Dongdong D; Guo, Liping L; Wang, Na N; Xiang, Jing J; Song, Hongtao H; Sun, Jianjun J; Jiang, Jie J; Cui, Yimin Y

Publication Date: 2022-12

Variant appearance in text: rs2231142

PubMed Link: 36453946

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacokinetics of gefitinib in elderly patients with EGFR-mutated advanced non-small cell lung cancer: a prospective study.

Bmc Pulmonary Medicine

Nio, Yuta Y; Ishida, Hiroo H; Matsumoto, Natsumi N; Kusumoto, Sojiro S; Kubota, Yutaro Y; Tsunoda, Takuya T; Sasaki, Yasutsuna Y; Fujita, Ken-Ichi KI

Publication Date: 2022-11-30

Variant appearance in text: ABCG2: Q141K; rs2231142

PubMed Link: 36451169

Variant Present in the following documents:

• Main text
• 12890_2022_Article_2249.pdf

View BVdb publication page

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