SNCA c.385_386delinsGG ;(p.S129G)

Variant ID: 4-90650349-GA-CC

NM_000345.3(SNCA):c.385_386delinsGG;(p.S129G)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein.

Plos One
Elfarrash, Sara S; Jensen, Nanna Møller NM; Ferreira, Nelson N; Schmidt, Sissel Ida SI; Gregersen, Emil E; Vestergaard, Marie Vibeke MV; Nabavi, Sadegh S; Meyer, Morten M; Jensen, Poul Henning PH
Publication Date: 2021

Variant appearance in text: SNCA: S129G
PubMed Link: 34613964
Variant Present in the following documents:
  • Main text
  • pone.0252635.pdf
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Organotypic hippocampal slices, an emerging tool to model synucleinopathies.

Neural Regeneration Research
Elfarrash, Sara S; Jensen, Poul Henning PH
Publication Date: 2021-05

Variant appearance in text: SNCA: S129G
PubMed Link: 33229751
Variant Present in the following documents:
  • Main text
  • NRR-16-999.pdf
View BVdb publication page



Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates.

Acta Neuropathologica Communications
Elfarrash, Sara S; Jensen, Nanna Møller NM; Ferreira, Nelson N; Betzer, Cristine C; Thevathasan, Jervis Vermal JV; Diekmann, Robin R; Adel, Mohamed M; Omar, Nisreen Mansour NM; Boraie, Mohamed Z MZ; Gad, Sabry S; Ries, Jonas J; Kirik, Deniz D; Nabavi, Sadegh S; Jensen, Poul Henning PH
Publication Date: 2019-12-19

Variant appearance in text: SNCA: S129G
PubMed Link: 31856920
Variant Present in the following documents:
  • Main text
  • 40478_2019_Article_865.pdf
View BVdb publication page



The role of lipids in α-synuclein misfolding and neurotoxicity.

The Journal Of Biological Chemistry
Ugalde, Cathryn L CL; Lawson, Victoria A VA; Finkelstein, David I DI; Hill, Andrew F AF
Publication Date: 2019-06-07

Variant appearance in text: SNCA: S129G
PubMed Link: 31064841
Variant Present in the following documents:
  • Main text
View BVdb publication page



Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast.

Biomolecules
Popova, Blagovesta B; Kleinknecht, Alexandra A; Braus, Gerhard H GH
Publication Date: 2015-04-23

Variant appearance in text: SNCA: S129G
PubMed Link: 25915624
Variant Present in the following documents:
  • Main text
View BVdb publication page



Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

Plos Genetics
Lázaro, Diana F DF; Rodrigues, Eva F EF; Langohr, Ramona R; Shahpasandzadeh, Hedieh H; Ribeiro, Thales T; Guerreiro, Patrícia P; Gerhardt, Ellen E; Kröhnert, Katharina K; Klucken, Jochen J; Pereira, Marcos D MD; Popova, Blagovesta B; Kruse, Niels N; Mollenhauer, Brit B; Rizzoli, Silvio O SO; Braus, Gerhard H GH; Danzer, Karin M KM; Outeiro, Tiago F TF
Publication Date: 2014-11

Variant appearance in text: SNCA: S129G
PubMed Link: 25393002
Variant Present in the following documents:
  • Main text
  • pgen.1004741.pdf
View BVdb publication page