Publications:

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Tyrosine 136 phosphorylation of α-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2.

Acta Neuropathologica Communications

Sano, Kazunori K; Iwasaki, Yasushi Y; Yamashita, Yuta Y; Irie, Keiichi K; Hosokawa, Masato M; Satoh, Katsuya K; Mishima, Kenichi K

Publication Date: 2021-11-12

Variant appearance in text: SNCA: Y125F

PubMed Link: 34772466

Variant Present in the following documents:

• 40478_2021_Article_1281.pdf

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α-Synuclein Trafficking in Parkinson's Disease: Insights From Fly and Mouse Models.

Asn Neuro

Cheng, Jingjing J; Lu, Qingqing Q; Song, Li L; Ho, Margaret S MS

Publication Date: 2018

Variant appearance in text: SNCA: Y125F

PubMed Link: 30482039

Variant Present in the following documents:

• Main text
• 10.1177_1759091418812587.pdf

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α-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease.

The Embo Journal

Kang, Seong Su SS; Ahn, Eun Hee EH; Zhang, Zhentao Z; Liu, Xia X; Manfredsson, Fredric P FP; Sandoval, Ivette M IM; Dhakal, Susov S; Iuvone, P Michael PM; Cao, Xuebing X; Ye, Keqiang K

Publication Date: 2018-06-15

Variant appearance in text: SNCA: Y125F

PubMed Link: 29769405

Variant Present in the following documents:

• Main text

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TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Kang, Seong Su SS; Zhang, Zhentao Z; Liu, Xia X; Manfredsson, Fredric P FP; Benskey, Matthew J MJ; Cao, Xuebing X; Xu, Jun J; Sun, Yi E YE; Ye, Keqiang K

Publication Date: 2017-10-03

Variant appearance in text: SNCA: Y125F

PubMed Link: 28923922

Variant Present in the following documents:

• Main text

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Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease.

Nature Structural & Molecular Biology

Zhang, Zhentao Z; Kang, Seong Su SS; Liu, Xia X; Ahn, Eun Hee EH; Zhang, Zhaohui Z; He, Li L; Iuvone, P Michael PM; Duong, Duc M DM; Seyfried, Nicholas T NT; Benskey, Matthew J MJ; Manfredsson, Fredric P FP; Jin, Lingjing L; Sun, Yi E YE; Wang, Jian-Zhi JZ; Ye, Keqiang K

Publication Date: 2017-08

Variant appearance in text: SNCA: Y125F

PubMed Link: 28671665

Variant Present in the following documents:

• Main text

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α-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillation.

Bmc Biophysics

Bai, Jia J; Zhang, Zeting Z; Liu, Maili M; Li, Conggang C

Publication Date: 2015

Variant appearance in text: NACP: Y125F

PubMed Link: 26843956

Variant Present in the following documents:

• 13628_2016_Article_26.pdf

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Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

Plos Genetics

Lázaro, Diana F DF; Rodrigues, Eva F EF; Langohr, Ramona R; Shahpasandzadeh, Hedieh H; Ribeiro, Thales T; Guerreiro, Patrícia P; Gerhardt, Ellen E; Kröhnert, Katharina K; Klucken, Jochen J; Pereira, Marcos D MD; Popova, Blagovesta B; Kruse, Niels N; Mollenhauer, Brit B; Rizzoli, Silvio O SO; Braus, Gerhard H GH; Danzer, Karin M KM; Outeiro, Tiago F TF

Publication Date: 2014-11

Variant appearance in text: SNCA: Y125F

PubMed Link: 25393002

Variant Present in the following documents:

• Main text
• pgen.1004741.pdf

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c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.

Human Molecular Genetics

Mahul-Mellier, Anne-Laure AL; Fauvet, Bruno B; Gysbers, Amanda A; Dikiy, Igor I; Oueslati, Abid A; Georgeon, Sandrine S; Lamontanara, Allan J AJ; Bisquertt, Alejandro A; Eliezer, David D; Masliah, Eliezer E; Halliday, Glenda G; Hantschel, Oliver O; Lashuel, Hilal A HA

Publication Date: 2014-06-01

Variant appearance in text: SNCA: Y125F

PubMed Link: 24412932

Variant Present in the following documents:

• Main text

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