Publications:

Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson's disease.

Bmb Reports

Yoo, Hajung H; Lee, Jeongmin J; Kim, Bokwang B; Moon, Heechang H; Jeong, Huisu H; Lee, Kyungmi K; Song, Woo Jeung WJ; Hur, Junho K JK; Oh, Yohan Y

Publication Date: 2022-07

Variant appearance in text: SNCA: S87A

PubMed Link: 35733294

Variant Present in the following documents:

• bmb-55-7-323.pdf

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Death-associated Protein Kinase 1 Phosphorylates α-Synuclein at Ser129 and Exacerbates Rotenone-induced Toxic Aggregation of α-Synuclein in Dopaminergic SH-SY5Y Cells.

Experimental Neurobiology

Shin, Woo Hyun WH; Chung, Kwang Chul KC

Publication Date: 2020-06-30

Variant appearance in text: SNCA: S87A

PubMed Link: 32624505

Variant Present in the following documents:

• Main text
• EN-29-207.pdf

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Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

Plos Genetics

Lázaro, Diana F DF; Rodrigues, Eva F EF; Langohr, Ramona R; Shahpasandzadeh, Hedieh H; Ribeiro, Thales T; Guerreiro, Patrícia P; Gerhardt, Ellen E; Kröhnert, Katharina K; Klucken, Jochen J; Pereira, Marcos D MD; Popova, Blagovesta B; Kruse, Niels N; Mollenhauer, Brit B; Rizzoli, Silvio O SO; Braus, Gerhard H GH; Danzer, Karin M KM; Outeiro, Tiago F TF

Publication Date: 2014-11

Variant appearance in text: SNCA: S87A

PubMed Link: 25393002

Variant Present in the following documents:

• Main text
• pgen.1004741.pdf

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Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

The Journal Of Biological Chemistry

Paleologou, Katerina E KE; Schmid, Adrian W AW; Rospigliosi, Carla C CC; Kim, Hai-Young HY; Lamberto, Gonzalo R GR; Fredenburg, Ross A RA; Lansbury, Peter T PT; Fernandez, Claudio O CO; Eliezer, David D; Zweckstetter, Markus M; Lashuel, Hilal A HA

Publication Date: 2008-06-13

Variant appearance in text: SNCA: S87A

PubMed Link: 18343814

Variant Present in the following documents:

• Main text

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