Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.
Translational Neurodegeneration
Drobny, Alice A; Boros, Fanni Annamária FA; Balta, Denise D; Prieto Huarcaya, Susy S; Caylioglu, Deniz D; Qazi, Niyeti N; Vandrey, Julia J; Schneider, Yanni Y; Dobert, Jan Philipp JP; Pitcairn, Caleb C; Mazzulli, Joseph Robert JR; Zunke, Friederike F
Analysis of rare Parkinson's disease variants in millions of people.
Research Square
Pitz, Vanessa V; Makarious, Mary M; Bandrés-Ciga, Sara S; Iwaki, Hirotaka H; Singleton, Andrew A; Nalls, Mike M; Heilbron, Karl K; Blauwendraat, Cornelis C
Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Shum, Andrew A; Zaichick, Sofia S; McElroy, Gregory S GS; D'Alessandro, Karis K; Alasady, Milad J MJ; Novakovic, Michaela M; Peng, Wesley W; Grebenik, Ekaterina A EA; Chung, Daayun D; Flanagan, Margaret E ME; Smith, Roger R; Morales, Alejandro A; Stumpf, Laetitia L; McGrath, Kaitlyn K; Krainc, Dimitri D; Mendillo, Marc L ML; Prakriya, Murali M; Chandel, Navdeep S NS; Caraveo, Gabriela G
Genetics of Neurogenic Orthostatic Hypotension in Parkinson's Disease, Results from a Cross-Sectional In Silico Study.
Brain Sciences
Chevalier, Guenson G; Udovin, Lucas L; Otero-Losada, Matilde M; Bordet, Sofia S; Capani, Francisco F; Luo, Sheng S; Goetz, Christopher G CG; Perez-Lloret, Santiago S
Determining the Location of the α-Synuclein Dimer Interface Using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry.
Journal Of The American Society For Mass Spectrometry
Jeacock, Kiani K; Chappard, Alexandre A; Gallagher, Kelly J KJ; Mackay, C Logan CL; Kilgour, David P A DPA; Horrocks, Mathew H MH; Kunath, Tilo T; Clarke, David J DJ
The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism.
Cell Genomics
Bressan, Elisangela E; Reed, Xylena X; Bansal, Vikas V; Hutchins, Elizabeth E; Cobb, Melanie M MM; Webb, Michelle G MG; Alsop, Eric E; Grenn, Francis P FP; Illarionova, Anastasia A; Savytska, Natalia N; Violich, Ivo I; Broeer, Stefanie S; Fernandes, Noémia N; Sivakumar, Ramiyapriya R; Beilina, Alexandra A; Billingsley, Kimberley J KJ; Berghausen, Joos J; Pantazis, Caroline B CB; Pitz, Vanessa V; Patel, Dhairya D; Daida, Kensuke K; Meechoovet, Bessie B; Reiman, Rebecca R; Courtright-Lim, Amanda A; Logemann, Amber A; Antone, Jerry J; Barch, Mariya M; Kitchen, Robert R; Li, Yan Y; Dalgard, Clifton L CL; , ; Rizzu, Patrizia P; Hernandez, Dena G DG; Hjelm, Brooke E BE; Nalls, Mike M; Gibbs, J Raphael JR; Finkbeiner, Steven S; Cookson, Mark R MR; Van Keuren-Jensen, Kendall K; Craig, David W DW; Singleton, Andrew B AB; Heutink, Peter P; Blauwendraat, Cornelis C
Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synuclein.
Croft, Cara L CL; Paterno, Giavanna G; Vause, Ava R AR; Rowe, Lyla A LA; Ryu, Daniel H DH; Goodwin, Marshall S MS; Moran, Corey A CA; Cruz, Pedro E PE; Giasson, Benoit I BI; Golde, Todd E TE