APC c.176_177inv ;(p.A59E)

Variant ID: 5-112102063-CT-AG

NM_000038.5(APC):c.176_177inv;(p.A59E)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer.

Cell Death And Differentiation
Ramesh, Prashanthi P; Lannagan, Tamsin R M TRM; Jackstadt, Rene R; Atencia Taboada, Lidia L; Lansu, Nico N; Wirapati, Pratyaksha P; van Hooff, Sander R SR; Dekker, Danielle D; Pritchard, Jessica J; Kirov, Aleksandar B AB; van Neerven, Sanne M SM; Tejpar, Sabine S; Kops, Geert J P L GJPL; Sansom, Owen J OJ; Medema, Jan Paul JP
Publication Date: 2021-12

Variant appearance in text: APC: A59E
PubMed Link: 34117376
Variant Present in the following documents:
  • Main text
View BVdb publication page



Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.

Genome Research
Maher, Geoffrey J GJ; Ralph, Hannah K HK; Ding, Zhihao Z; Koelling, Nils N; Mlcochova, Hana H; Giannoulatou, Eleni E; Dhami, Pawan P; Paul, Dirk S DS; Stricker, Stefan H SH; Beck, Stephan S; McVean, Gilean G; Wilkie, Andrew O M AOM; Goriely, Anne A
Publication Date: 2018-12

Variant appearance in text: APC: Ala59Glu
PubMed Link: 30355600
Variant Present in the following documents:
  • 1779.pdf
View BVdb publication page



Identification of genomic and molecular traits that present therapeutic vulnerability to HGF-targeted therapy in glioblastoma.

Neuro-Oncology
Sa, Jason K JK; Kim, Sung Heon SH; Lee, Jin-Ku JK; Cho, Hee Jin HJ; Shin, Yong Jae YJ; Shin, Hyemi H; Koo, Harim H; Kim, Donggeon D; Lee, Mijeong M; Kang, Wonyoung W; Hong, Sung Hee SH; Kim, Jung Yong JY; Park, Young-Whan YW; Song, Seong-Won SW; Lee, Song-Jae SJ; Joo, Kyeung Min KM; Nam, Do-Hyun DH
Publication Date: 2019-02-14

Variant appearance in text: APC: A59E
PubMed Link: 29939324
Variant Present in the following documents:
  • Main text
View BVdb publication page