APC c.375T>A ;(p.N125K)

Variant ID: 5-112103040-T-A

NM_000038.5(APC):c.375T>A;(p.N125K)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth.

Science Advances
Shin, Seung-Min SM; Kim, Ji-Sun JS; Park, Seong-Wook SW; Jun, Sei-Yong SY; Kweon, Hye-Jin HJ; Choi, Dong-Ki DK; Lee, Dakeun D; Cho, Yong Beom YB; Kim, Yong-Sung YS
Publication Date: 2020-01

Variant appearance in text: APC: N125K
PubMed Link: 31998840
Variant Present in the following documents:
  • aay2174_SM.pdf
View BVdb publication page



A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.

Scientific Reports
Menon, Malini M; Elliott, Richard R; Bowers, Leandra L; Balan, Nicolae N; Rafiq, Rumana R; Costa-Cabral, Sara S; Munkonge, Felix F; Trinidade, Ines I; Porter, Roderick R; Campbell, Andrew D AD; Johnson, Emma R ER; Esdar, Christina C; Buchstaller, Hans-Peter HP; Leuthner, Birgitta B; Rohdich, Felix F; Schneider, Richard R; Sansom, Owen O; Wienke, Dirk D; Ashworth, Alan A; Lord, Christopher J CJ
Publication Date: 2019-01-17

Variant appearance in text: APC: N125K
PubMed Link: 30655555
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_36447.pdf
View BVdb publication page