APC c.556_558delinsCAT ;(p.R186H)

Variant ID: 5-112116511-AGA-CAT

NM_000038.5(APC):c.556_558delinsCAT;(p.R186H)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Characterization of Clonal Evolution in Microsatellite Unstable Metastatic Cancers through Multiregional Tumor Sequencing.

Molecular Cancer Research : Mcr
Bonneville, Russell R; Paruchuri, Anoosha A; Wing, Michele R MR; Krook, Melanie A MA; Reeser, Julie W JW; Chen, Hui-Zi HZ; Dao, Thuy T; Samorodnitsky, Eric E; Smith, Amy M AM; Yu, Lianbo L; Nowacki, Nicholas N; Chen, Wei W; Roychowdhury, Sameek S
Publication Date: 2021-03

Variant appearance in text: APC: R186H
PubMed Link: 33229401
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of genetic alterations identifies the frequent mutation of GNAS in colorectal laterally spreading tumors.

Cancer Communications (London, England)
Nong, Yanying Y; Zhang, Yuru Y; Zhang, Yi Y; Pan, Lei L; Chen, Junsheng J; Zhu, Chaojun C; Han, Lu L; Li, Aimin A; Liu, Side S
Publication Date: 2020-11

Variant appearance in text: APC: R186H
PubMed Link: 32762003
Variant Present in the following documents:
  • Main text
View BVdb publication page



The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review.

Journal Of Cancer Research And Clinical Oncology
Lin, Yu-Lin YL; Ma, Ru R; Li, Yan Y
Publication Date: 2020-09

Variant appearance in text: APC: R186H
PubMed Link: 32700107
Variant Present in the following documents:
  • Main text
  • 432_2020_Article_3321.pdf
View BVdb publication page



Development and clinical application of an integrative genomic approach to personalized cancer therapy.

Genome Medicine
Uzilov, Andrew V AV; Ding, Wei W; Fink, Marc Y MY; Antipin, Yevgeniy Y; Brohl, Andrew S AS; Davis, Claire C; Lau, Chun Yee CY; Pandya, Chetanya C; Shah, Hardik H; Kasai, Yumi Y; Powell, James J; Micchelli, Mark M; Castellanos, Rafael R; Zhang, Zhongyang Z; Linderman, Michael M; Kinoshita, Yayoi Y; Zweig, Micol M; Raustad, Katie K; Cheung, Kakit K; Castillo, Diane D; Wooten, Melissa M; Bourzgui, Imane I; Newman, Leah C LC; Deikus, Gintaras G; Mathew, Bino B; Zhu, Jun J; Glicksberg, Benjamin S BS; Moe, Aye S AS; Liao, Jun J; Edelmann, Lisa L; Dudley, Joel T JT; Maki, Robert G RG; Kasarskis, Andrew A; Holcombe, Randall F RF; Mahajan, Milind M; Hao, Ke K; Reva, Boris B; Longtine, Janina J; Starcevic, Daniela D; Sebra, Robert R; Donovan, Michael J MJ; Li, Shuyu S; Schadt, Eric E EE; Chen, Rong R
Publication Date: 2016-06-01

Variant appearance in text: APC: R186H
PubMed Link: 27245685
Variant Present in the following documents:
  • 13073_2016_313_MOESM1_ESM.xlsx, sheet 5
View BVdb publication page



Deregulation of Rho GTPases in cancer.

Small Gtpases
Porter, Andrew P AP; Papaioannou, Alexandra A; Malliri, Angeliki A
Publication Date: 2016-07-02

Variant appearance in text: APC: R186H
PubMed Link: 27104658
Variant Present in the following documents:
  • Main text
  • ksgt-07-03-1173767.pdf
View BVdb publication page



Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.

Plos One
de Leng, Wendy W J WW; Gadellaa-van Hooijdonk, Christa G CG; Barendregt-Smouter, Françoise A S FA; Koudijs, Marco J MJ; Nijman, Ies I; Hinrichs, John W J JW; Cuppen, Edwin E; van Lieshout, Stef S; Loberg, Robert D RD; de Jonge, Maja M; Voest, Emile E EE; de Weger, Roel A RA; Steeghs, Neeltje N; Langenberg, Marlies H G MH; Sleijfer, Stefan S; Willems, Stefan M SM; Lolkema, Martijn P MP
Publication Date: 2016

Variant appearance in text: APC: R186H
PubMed Link: 26919633
Variant Present in the following documents:
  • pone.0149405.s010.xlsx, sheet 2
  • pone.0149405.s010.xlsx, sheet 1
View BVdb publication page