APC c.646-3774T>G

Variant ID: 5-112124369-T-G

NM_000038.5(APC):c.646-3774T>G

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway.

Oncotarget
Li, Fei-Feng FF; Zhao, Zhi-Xun ZX; Yan, Peng P; Wang, Song S; Liu, Zheng Z; Zhang, Qiong Q; Zhang, Xiao-Ning XN; Sun, Chang-Hao CH; Wang, Xi-Shan XS; Wang, Gui-Yu GY; Liu, Shu-Lin SL
Publication Date: 2017-09-19

Variant appearance in text: rs2431238
PubMed Link: 29050326
Variant Present in the following documents:
  • Main text
  • oncotarget-08-70854.pdf
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Inherited Variants in Wnt Pathway Genes Influence Outcomes of Prostate Cancer Patients Receiving Androgen Deprivation Therapy.

International Journal Of Molecular Sciences
Geng, Jiun-Hung JH; Lin, Victor C VC; Yu, Chia-Cheng CC; Huang, Chao-Yuan CY; Yin, Hsin-Ling HL; Chang, Ta-Yuan TY; Lu, Te-Ling TL; Huang, Shu-Pin SP; Bao, Bo-Ying BY
Publication Date: 2016-11-26

Variant appearance in text: rs2431238
PubMed Link: 27898031
Variant Present in the following documents:
  • Main text
  • ijms-17-01970.pdf
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Germline Genetic Variants in the Wnt/β-Catenin Pathway as Predictors of Colorectal Cancer Risk.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Hildebrandt, Michelle A T MA; Reyes, Monica E ME; Lin, Moubin M; He, Yonggang Y; Nguyen, Son V SV; Hawk, Ernest T ET; Wu, Xifeng X
Publication Date: 2016-03

Variant appearance in text: rs2431238
PubMed Link: 26809274
Variant Present in the following documents:
  • Main text
View BVdb publication page



Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Plos One
Wang, Jingbo J; Wang, Xu X; Zhao, Mingjue M; Choo, Su Pin SP; Ong, Sin Jen SJ; Ong, Simon Y K SY; Chong, Samuel S SS; Teo, Yik Ying YY; Lee, Caroline G L CG
Publication Date: 2014

Variant appearance in text: rs2431238
PubMed Link: 25372392
Variant Present in the following documents:
  • Main text
  • pone.0111694.pdf
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Targeted re-sequencing identified rs3106189 at the 5' UTR of TAPBP and rs1052918 at the 3' UTR of TCF3 to be associated with the overall survival of colorectal cancer patients.

Plos One
Shao, Jiaofang J; Lou, Xiaoyan X; Wang, Jun J; Zhang, Jing J; Chen, Chen C; Hua, Dasong D; Mo, Fan F; Han, Xu X; Zheng, Shu S; Lin, Biaoyang B
Publication Date: 2013

Variant appearance in text: rs2431238
PubMed Link: 23940558
Variant Present in the following documents:
  • pone.0070307.s002.xlsx, sheet 1
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Interaction of polymorphisms in mitotic regulator genes with cigarette smoking and pancreatic cancer risk.

Molecular Carcinogenesis
Jang, Ji-Hyun JH; Cotterchio, Michelle M; Borgida, Ayelet A; Liu, Geoffrey G; Gallinger, Steven S; Cleary, Sean P SP
Publication Date: 2013-11

Variant appearance in text: rs2431238
PubMed Link: 23908141
Variant Present in the following documents:
  • Main text
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A replication study and genome-wide scan of single-nucleotide polymorphisms associated with pancreatic cancer risk and overall survival.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Willis, Jason A JA; Olson, Sara H SH; Orlow, Irene I; Mukherjee, Semanti S; McWilliams, Robert R RR; Kurtz, Robert C RC; Klein, Robert J RJ
Publication Date: 2012-07-15

Variant appearance in text: rs2431238
PubMed Link: 22665904
Variant Present in the following documents:
  • Main text
View BVdb publication page



Increased variance in germline allele-specific expression of APC associates with colorectal cancer.

Gastroenterology
Curia, Maria Cristina MC; De Iure, Sabrina S; De Lellis, Laura L; Veschi, Serena S; Mammarella, Sandra S; White, Marquitta J MJ; Bartlett, Jacquelaine J; Di Iorio, Angelo A; Amatetti, Cristina C; Lombardo, Marco M; Di Gregorio, Patrizia P; Battista, Pasquale P; Mariani-Costantini, Renato R; Williams, Scott M SM; Cama, Alessandro A
Publication Date: 2012-01

Variant appearance in text: rs2431238
PubMed Link: 21995949
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Couch, Fergus J FJ; Wang, Xianshu X; Bamlet, William R WR; de Andrade, Mariza M; Petersen, Gloria M GM; McWilliams, Robert R RR
Publication Date: 2010-01

Variant appearance in text: rs2431238
PubMed Link: 20056645
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Wang, Xianshu X; Goode, Ellen L EL; Fredericksen, Zachary S ZS; Vierkant, Robert A RA; Pankratz, V Shane VS; Liu-Mares, Wen W; Rider, David N DN; Vachon, Celine M CM; Cerhan, James R JR; Olson, Janet E JE; Couch, Fergus J FJ
Publication Date: 2008-08

Variant appearance in text: rs2431238
PubMed Link: 18708403
Variant Present in the following documents:
  • Main text
View BVdb publication page