DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
Journal For Immunotherapy Of Cancer
Muik, Alexander A; Adams 3rd, Homer C HC; Gieseke, Friederike F; Altintas, Isil I; Schoedel, Kristina B KB; Blum, Jordan M JM; Sänger, Bianca B; Burm, Saskia M SM; Stanganello, Eliana E; Verzijl, Dennis D; Spires, Vanessa M VM; Vascotto, Fulvia F; Toker, Aras A; Quinkhardt, Juliane J; Fereshteh, Mark M; Diken, Mustafa M; Satijn, David P E DPE; Kreiter, Sebastian S; Ahmadi, Tahamtan T; Breij, Esther C W ECW; Türeci, Özlem Ö; Sasser, Kate K; Sahin, Ugur U; Jure-Kunkel, Maria M
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Cancer Discovery
Muik, Alexander A; Garralda, Elena E; Altintas, Isil I; Gieseke, Friederike F; Geva, Ravit R; Ben-Ami, Eytan E; Maurice-Dror, Corinne C; Calvo, Emiliano E; LoRusso, Patricia M PM; Alonso, Guzman G; Rodriguez-Ruiz, Maria E ME; Schoedel, Kristina B KB; Blum, Jordan M JM; Sänger, Bianca B; Salcedo, Theodora W TW; Burm, Saskia M SM; Stanganello, Eliana E; Verzijl, Dennis D; Vascotto, Fulvia F; Sette, Angelica A; Quinkhardt, Juliane J; Plantinga, Theo S TS; Toker, Aras A; van den Brink, Edward N EN; Fereshteh, Mark M; Diken, Mustafa M; Satijn, David D; Kreiter, Sebastian S; Breij, Esther C W ECW; Bajaj, Gaurav G; Lagkadinou, Eleni E; Sasser, Kate K; Türeci, Özlem Ö; Forssmann, Ulf U; Ahmadi, Tahamtan T; Şahin, Uğur U; Jure-Kunkel, Maria M; Melero, Ignacio I
Potent preclinical activity of HexaBody-DR5/DR5 in relapsed and/or refractory multiple myeloma.
Blood Advances
van der Horst, Hilma J HJ; Gelderloos, Anne T AT; Chamuleau, Martine E D MED; Breij, Esther C W ECW; Zweegman, Sonja S; Nijhof, Inger S IS; Overdijk, Marije B MB; Mutis, Tuna T