APC c.700C>T ;(p.L234F)

Variant ID: 5-112128197-C-T

NM_000038.5(APC):c.700C>T;(p.L234F)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


The unique properties of IgG4 and its roles in health and disease.

Nature Reviews. Immunology
Rispens, Theo T; Huijbers, Maartje G MG
Publication Date: 2023-04-24

Variant appearance in text: APC: L234F
PubMed Link: 37095254
Variant Present in the following documents:
  • 41577_2023_Article_871.pdf
View BVdb publication page



DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.

Journal For Immunotherapy Of Cancer
Muik, Alexander A; Adams 3rd, Homer C HC; Gieseke, Friederike F; Altintas, Isil I; Schoedel, Kristina B KB; Blum, Jordan M JM; Sänger, Bianca B; Burm, Saskia M SM; Stanganello, Eliana E; Verzijl, Dennis D; Spires, Vanessa M VM; Vascotto, Fulvia F; Toker, Aras A; Quinkhardt, Juliane J; Fereshteh, Mark M; Diken, Mustafa M; Satijn, David P E DPE; Kreiter, Sebastian S; Ahmadi, Tahamtan T; Breij, Esther C W ECW; Türeci, Özlem Ö; Sasser, Kate K; Sahin, Ugur U; Jure-Kunkel, Maria M
Publication Date: 2022-06

Variant appearance in text: APC: L234F
PubMed Link: 35688554
Variant Present in the following documents:
  • Main text
  • jitc-2021-004322.pdf
  • jitc-2021-004322supp001.pdf
View BVdb publication page



Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.

Cancer Discovery
Muik, Alexander A; Garralda, Elena E; Altintas, Isil I; Gieseke, Friederike F; Geva, Ravit R; Ben-Ami, Eytan E; Maurice-Dror, Corinne C; Calvo, Emiliano E; LoRusso, Patricia M PM; Alonso, Guzman G; Rodriguez-Ruiz, Maria E ME; Schoedel, Kristina B KB; Blum, Jordan M JM; Sänger, Bianca B; Salcedo, Theodora W TW; Burm, Saskia M SM; Stanganello, Eliana E; Verzijl, Dennis D; Vascotto, Fulvia F; Sette, Angelica A; Quinkhardt, Juliane J; Plantinga, Theo S TS; Toker, Aras A; van den Brink, Edward N EN; Fereshteh, Mark M; Diken, Mustafa M; Satijn, David D; Kreiter, Sebastian S; Breij, Esther C W ECW; Bajaj, Gaurav G; Lagkadinou, Eleni E; Sasser, Kate K; Türeci, Özlem Ö; Forssmann, Ulf U; Ahmadi, Tahamtan T; Şahin, Uğur U; Jure-Kunkel, Maria M; Melero, Ignacio I
Publication Date: 2022-05-02

Variant appearance in text: APC: L234F
PubMed Link: 35176764
Variant Present in the following documents:
  • cd-21-1345_supplementary_figures_tables_and_methods_suppsm1.pdf
View BVdb publication page



The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.

International Journal Of Molecular Sciences
Gogesch, Patricia P; Dudek, Simone S; van Zandbergen, Ger G; Waibler, Zoe Z; Anzaghe, Martina M
Publication Date: 2021-08-19

Variant appearance in text: APC: L234F
PubMed Link: 34445651
Variant Present in the following documents:
  • Main text
  • ijms-22-08947.pdf
View BVdb publication page



Potent preclinical activity of HexaBody-DR5/DR5 in relapsed and/or refractory multiple myeloma.

Blood Advances
van der Horst, Hilma J HJ; Gelderloos, Anne T AT; Chamuleau, Martine E D MED; Breij, Esther C W ECW; Zweegman, Sonja S; Nijhof, Inger S IS; Overdijk, Marije B MB; Mutis, Tuna T
Publication Date: 2021-04-27

Variant appearance in text: APC: L234F
PubMed Link: 33885752
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment.

Antibodies (Basel, Switzerland)
Liu, Rena R; Oldham, Robert J RJ; Teal, Emma E; Beers, Stephen A SA; Cragg, Mark S MS
Publication Date: 2020-11-17

Variant appearance in text: APC: L234F
PubMed Link: 33212886
Variant Present in the following documents:
  • Main text
View BVdb publication page



Harnessing the immune system via FcγR function in immune therapy: a pathway to next-gen mAbs.

Immunology And Cell Biology
Chenoweth, Alicia M AM; Wines, Bruce D BD; Anania, Jessica C JC; Mark Hogarth, P P
Publication Date: 2020-04

Variant appearance in text: APC: L234F
PubMed Link: 32157732
Variant Present in the following documents:
  • IMCB-9999-na.pdf
View BVdb publication page