Publications:

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A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Donehower, Lawrence A LA; Scheurer, Michael E ME; Creighton, Chad J CJ

Publication Date: 2021-02-10

Variant appearance in text: APC: Arg850Ter

PubMed Link: 33568653

Variant Present in the following documents:

• 41467_2021_21081_MOESM8_ESM.xlsx, sheet 3

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Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

Nature Communications

Zaidi, Syed H SH; Harrison, Tabitha A TA; Phipps, Amanda I AI; Steinfelder, Robert R; Trinh, Quang M QM; Qu, Conghui C; Banbury, Barbara L BL; Georgeson, Peter P; Grasso, Catherine S CS; Giannakis, Marios M; Adams, Jeremy B JB; Alwers, Elizabeth E; Amitay, Efrat L EL; Barfield, Richard T RT; Berndt, Sonja I SI; Borozan, Ivan I; Brenner, Hermann H; Brezina, Stefanie S; Buchanan, Daniel D DD; Cao, Yin Y; Chan, Andrew T AT; Chang-Claude, Jenny J; Connolly, Charles M CM; Drew, David A DA; Farris, Alton Brad AB; Figueiredo, Jane C JC; French, Amy J AJ; Fuchs, Charles S CS; Garraway, Levi A LA; Gruber, Steve S; Guinter, Mark A MA; Hamilton, Stanley R SR; Harlid, Sophia S; Heisler, Lawrence E LE; Hidaka, Akihisa A; Hopper, John L JL; Huang, Wen-Yi WY; Huyghe, Jeroen R JR; Jenkins, Mark A MA; Krzyzanowski, Paul M PM; Lemire, Mathieu M; Lin, Yi Y; Luo, Xuemei X; Mardis, Elaine R ER; McPherson, John D JD; Miller, Jessica K JK; Moreno, Victor V; Mu, Xinmeng Jasmine XJ; Nishihara, Reiko R; Papadopoulos, Nickolas N; Pasternack, Danielle D; Quist, Michael J MJ; Rafikova, Adilya A; Reid, Emma E G EEG; Shinbrot, Eve E; Shirts, Brian H BH; Stein, Lincoln D LD; Teney, Cherie D CD; Timms, Lee L; Um, Caroline Y CY; Van Guelpen, Bethany B; Van Tassel, Megan M; Wang, Xiaolong X; Wheeler, David A DA; Yung, Christina K CK; Hsu, Li L; Ogino, Shuji S; Gsur, Andrea A; Newcomb, Polly A PA; Gallinger, Steven S; Hoffmeister, Michael M; Campbell, Peter T PT; Thibodeau, Stephen N SN; Sun, Wei W; Hudson, Thomas J TJ; Peters, Ulrike U

Publication Date: 2020-07-20

Variant appearance in text: APC: R850X

PubMed Link: 32686686

Variant Present in the following documents:

• 41467_2020_17386_MOESM4_ESM.xlsx, sheet 1

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The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget

Liu, Zhe Z; Yang, Chao C; Li, Xiangchun X; Luo, Wen W; Roy, Bhaskar B; Xiong, Teng T; Zhang, Xiuqing X; Yang, Huanming H; Wang, Jian J; Ye, Zhenhao Z; Chen, Yang Y; Song, Jinghe J; Ma, Shuai S; Zhou, Yong Y; Yang, Min M; Fang, Xiaodong X; Du, Jie J

Publication Date: 2018-06-08

Variant appearance in text: APC: 2548A>T; R850*

PubMed Link: 29937994

Variant Present in the following documents:

• oncotarget-09-27412-s004.xlsx, sheet 1

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Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis.

Plos One

Jang, Bo Gun BG; Lee, Byung Lan BL; Kim, Woo Ho WH

Publication Date: 2013

Variant appearance in text: APC: R850X

PubMed Link: 24340024

Variant Present in the following documents:

• Main text

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A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts.

Gut

Leedham, Simon J SJ; Rodenas-Cuadrado, Pedro P; Howarth, Kimberley K; Lewis, Annabelle A; Mallappa, Sreelakshmi S; Segditsas, Stefania S; Davis, Hayley H; Jeffery, Rosemary R; Rodriguez-Justo, Manuel M; Keshav, Satish S; Travis, Simon P L SP; Graham, Trevor A TA; East, James J; Clark, Susan S; Tomlinson, Ian P M IP

Publication Date: 2013-01

Variant appearance in text: APC: R850X

PubMed Link: 22287596

Variant Present in the following documents:

• Main text
• gutjnl-2011-301601.pdf

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The C-terminus of Apc does not influence intestinal adenoma development or progression.

The Journal Of Pathology

Lewis, Annabelle A; Davis, Hayley H; Deheragoda, Maesha M; Pollard, Patrick P; Nye, Emma E; Jeffery, Rosemary R; Segditsas, Stefania S; East, Philip P; Poulsom, Richard R; Stamp, Gordon G; Wright, Nicholas N; Tomlinson, Ian I

Publication Date: 2012-01

Variant appearance in text: APC: R850X

PubMed Link: 22009253

Variant Present in the following documents:

• Main text

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Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.

Gut

Lewis, Annabelle A; Segditsas, Stefania S; Deheragoda, Maesha M; Pollard, Patrick P; Jeffery, Rosemary R; Nye, Emma E; Lockstone, Helen H; Davis, Hayley H; Clark, Susan S; Stamp, Gordon G; Poulsom, Richard R; Wright, Nicholas N; Tomlinson, Ian I

Publication Date: 2010-12

Variant appearance in text: APC: R850X

PubMed Link: 20926645

Variant Present in the following documents:

• Main text

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Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.

Human Molecular Genetics

Segditsas, Stefania S; Sieber, Oliver O; Deheragoda, Maesha M; East, Phil P; Rowan, Andrew A; Jeffery, Rosemary R; Nye, Emma E; Clark, Susan S; Spencer-Dene, Bradley B; Stamp, Gordon G; Poulsom, Richard R; Suraweera, Nirosha N; Silver, Andrew A; Ilyas, Mohammad M; Tomlinson, Ian I

Publication Date: 2008-12-15

Variant appearance in text: APC: R850X

PubMed Link: 18782851

Variant Present in the following documents:

• Main text
• ddn286.pdf

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