APC c.2815A>T ;(p.K939*)

Variant ID: 5-112174106-A-T

NM_000038.5(APC):c.2815A>T;(p.K939*)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: APC: K939*
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.

Gut
Kleeman, Sam O SO; Koelzer, Viktor H VH; Jones, Helen Js HJ; Vazquez, Ester Gil EG; Davis, Hayley H; East, James E JE; Arnold, Roland R; Koppens, Martijn Aj MA; Blake, Andrew A; Domingo, Enric E; Cunningham, Chris C; Beggs, Andrew D AD; Pestinger, Valerie V; Loughrey, Maurice B MB; Wang, Lai-Mun LM; Lannagan, Tamsin Rm TR; Woods, Susan L SL; Worthley, Daniel D; Consortium, S Cort SC; Tomlinson, Ian I; Dunne, Philip D PD; Maughan, Timothy T; Leedham, Simon J SJ
Publication Date: 2020-06

Variant appearance in text: APC: 2815A>T; K939*
PubMed Link: 31563876
Variant Present in the following documents:
  • gutjnl-2019-319126supp003.xlsx, sheet 3
View BVdb publication page



Human colon organoids reveal distinct physiologic and oncogenic Wnt responses.

The Journal Of Experimental Medicine
Michels, Birgitta E BE; Mosa, Mohammed H MH; Grebbin, Britta M BM; Yepes, Diego D; Darvishi, Tahmineh T; Hausmann, Johannes J; Urlaub, Henning H; Zeuzem, Stefan S; Kvasnicka, Hans M HM; Oellerich, Thomas T; Farin, Henner F HF
Publication Date: 2019-03-04

Variant appearance in text: APC: K939*
PubMed Link: 30792186
Variant Present in the following documents:
  • JEM_20180823_TableS5.xlsx, sheet 3
View BVdb publication page



StrandAdvantage test for early-line and advanced-stage treatment decisions in solid tumors.

Cancer Medicine
Sen, Manimala M; Katragadda, Shanmukh S; Ravichandran, Aarthi A; Deshpande, Gouri G; Parulekar, Minothi M; Nayanala, Swetha S; Vittal, Vikram V; Shen, Weiming W; Phooi Nee Yong, Melanie M; Jacob, Jemima J; Parchuru, Sravanthi S; Dhanuskodi, Kalpana K; Eyring, Kenneth K; Agrawal, Pooja P; Agarwal, Smita S; Shanmugam, Ashwini A; Gupta, Satish S; Vishwanath, Divya D; Kumari, Kiran K; Hariharan, Arun K AK; Balaji, Sai A SA; Liang, Qiaoling Q; Robolledo, Belen B; Gauribidanur Raghavendrachar, Vijayashree V; Oomer Farooque, Mohammed M; Buresh, Cary J CJ; Ramamoorthy, Preveen P; Bahadur, Urvashi U; Subramanian, Kalyanasundaram K; Hariharan, Ramesh R; Veeramachaneni, Vamsi V; Sankaran, Satish S; Gupta, Vaijayanti V
Publication Date: 2017-05

Variant appearance in text: APC: Lys939Ter
PubMed Link: 28371134
Variant Present in the following documents:
  • CAM4-6-883-s002.xlsx, sheet 5
  • CAM4-6-883-s002.xlsx, sheet 21
View BVdb publication page



Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications
Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML
Publication Date: 2017-02-10

Variant appearance in text: APC: K939X
PubMed Link: 28186126
Variant Present in the following documents:
  • ncomms14262-s5.xlsx, sheet 2
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: APC: 2815A>T; K939*
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page