EGR1 c.133_134delinsAA ;(p.A45N)

Variant ID: 5-137801583-GC-AA

NM_001964.2(EGR1):c.133_134delinsAA;(p.A45N)

This variant was identified in 30 publications

View GRCh38 version.




Publications:


Deep learning model accurately classifies metastatic tumors from primary tumors based on mutational signatures.

Scientific Reports
Zheng, Weisheng W; Pu, Mengchen M; Li, Xiaorong X; Du, Zhaolan Z; Jin, Sutong S; Li, Xingshuai X; Zhou, Jielong J; Zhang, Yingsheng Y
Publication Date: 2023-05-30

Variant appearance in text: 225: A45N
PubMed Link: 37253775
Variant Present in the following documents:
  • 41598_2023_35842_MOESM8_ESM.xlsx, sheet 1
  • 41598_2023_35842_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Genomic and microenvironmental heterogeneity shaping epithelial-to-mesenchymal trajectories in cancer.

Nature Communications
Malagoli Tagliazucchi, Guidantonio G; Wiecek, Anna J AJ; Withnell, Eloise E; Secrier, Maria M
Publication Date: 2023-02-11

Variant appearance in text: 225: A45N
PubMed Link: 36774358
Variant Present in the following documents:
  • 41467_2023_36439_MOESM8_ESM.xlsx, sheet 34
View BVdb publication page



Identification of an unfolded protein response-related signature for predicting the prognosis of pancreatic ductal adenocarcinoma.

Frontiers In Oncology
Fang, Lishan L; Chen, Shaojing S; Gong, Hui H; Xia, Shaohua S; Guan, Sainan S; Quan, Nali N; Li, Yajie Y; Zeng, Chao C; Chen, Ya Y; Du, Jianhang J; Liu, Shuguang S
Publication Date: 2022

Variant appearance in text: 225: A45N
PubMed Link: 36727081
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



Overexpression of CENPL mRNA potentially regulated by miR-340-3p predicts the prognosis of pancreatic cancer patients.

Bmc Cancer
Cui, Zhongyuan Z; Du, Ling L; Wang, Jielong J; Li, Zhongzhuan Z; Xu, Jiehong J; Ou, Shiyu S; Li, Dongliang D; Li, Shasha S; Hu, Hanfang H; Chen, Gang G; Wu, Zhixian Z
Publication Date: 2022-12-26

Variant appearance in text: 225: A45N
PubMed Link: 36572856
Variant Present in the following documents:
  • 12885_2022_10450_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.

Nature Communications
Liu, Yuanhui Y; Azizian, Nancy G NG; Sullivan, Delaney K DK; Li, Yulin Y
Publication Date: 2022-11-17

Variant appearance in text: 225: A45N
PubMed Link: 36396656
Variant Present in the following documents:
  • 41467_2022_34890_MOESM11_ESM.xlsx, sheet 10
View BVdb publication page



Construction of immune-related signature and identification of S100A14 determining immune-suppressive microenvironment in pancreatic cancer.

Bmc Cancer
Wang, Chengcheng C; Chen, Yuan Y; Xinpeng, Yin Y; Xu, Ruiyuan R; Song, Jianlu J; Ruze, Rexiati R; Xu, Qiang Q; Zhao, Yupei Y
Publication Date: 2022-08-11

Variant appearance in text: 225: A45N
PubMed Link: 35953822
Variant Present in the following documents:
  • 12885_2022_9927_MOESM3_ESM.pdf
View BVdb publication page



Identification of Prognosis-Related Molecular Subgroups and Construction of a Prognostic Prediction Model Using Immune-Related Genes in Pancreatic Cancer.

Journal Of Oncology
Fei, Xiang X; Kong, Lingming L; Shi, Chao C; Wang, Gang G; Liu, Chenhai C; Wang, Cheng C; Liu, Peng P; Tan, Xiaodong X
Publication Date: 2022

Variant appearance in text: 225: A45N
PubMed Link: 35712127
Variant Present in the following documents:
  • 7117014.f1.xlsx, sheet 1
View BVdb publication page



Pan-Cancer Analysis, Reveals COVID-19-Related BSG as a Novel Marker for Treatment and Identification of Multiple Human Cancers.

Frontiers In Cell And Developmental Biology
Huang, Tao T; He, Wei-Ying WY
Publication Date: 2022

Variant appearance in text: 225: A45N
PubMed Link: 35646943
Variant Present in the following documents:
  • Table1.xlsx, sheet 5
View BVdb publication page



Tumor Microenvironment Profiling Identifies Prognostic Signatures and Suggests Immunotherapeutic Benefits in Neuroblastoma.

Frontiers In Cell And Developmental Biology
Feng, Chenzhao C; Li, Ting T; Xiao, Jun J; Wang, Jing J; Meng, Xinyao X; Niu, Huizhong H; Jiang, Bin B; Huang, Lei L; Deng, Xiaogeng X; Yan, Xueqiang X; Wu, Dianming D; Fang, Yifan Y; Lin, Yu Y; Chen, Feng F; Wu, Xiaojuan X; Zhao, Xiang X; Feng, Jiexiong J
Publication Date: 2022

Variant appearance in text: 225: A45N
PubMed Link: 35493068
Variant Present in the following documents:
  • Table1.xlsx, sheet 9
View BVdb publication page



CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma.

Frontiers In Oncology
Qiao, Juanli J; Tian, Yuan Y; Cheng, Xiaojing X; Liu, Zhaojun Z; Zhou, Jing J; Gu, Liankun L; Zhang, Baozhen B; Zhang, Lianhai L; Ji, Jiafu J; Xing, Rui R; Deng, Dajun D
Publication Date: 2021

Variant appearance in text: 225: A45N
PubMed Link: 35004325
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Embeddings from protein language models predict conservation and variant effects.

Human Genetics
Marquet, Céline C; Heinzinger, Michael M; Olenyi, Tobias T; Dallago, Christian C; Erckert, Kyra K; Bernhofer, Michael M; Nechaev, Dmitrii D; Rost, Burkhard B
Publication Date: 2022-10

Variant appearance in text: 225: A45N
PubMed Link: 34967936
Variant Present in the following documents:
  • 439_2021_2411_MOESM3_ESM.xlsx, sheet 34
View BVdb publication page



Long noncoding RNA SNHG1 promotes TERT expression by sponging miR-18b-5p in breast cancer.

Cell & Bioscience
Kang, Yujuan Y; Wan, Lin L; Wang, Qin Q; Yin, Yanling Y; Liu, Jiena J; Liu, Lei L; Wu, Hao H; Zhang, Lei L; Zhang, Xin X; Xu, Shouping S; Pang, Da D
Publication Date: 2021-08-31

Variant appearance in text: 225: A45N
PubMed Link: 34465388
Variant Present in the following documents:
  • 13578_2021_675_MOESM4_ESM.pdf
View BVdb publication page



TP53 isoform junction reads based analysis in malignant and normal contexts.

Scientific Reports
Vural, Suleyman S; Chang, Lun-Ching LC; Yee, Laura M LM; Sonkin, Dmitriy D
Publication Date: 2021-08-26

Variant appearance in text: 225: A45N
PubMed Link: 34446762
Variant Present in the following documents:
  • 41598_2021_96700_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Mapping Microproteins and ncRNA-Encoded Polypeptides in Different Mouse Tissues.

Frontiers In Cell And Developmental Biology
Pan, Ni N; Wang, Zhiwei Z; Wang, Bing B; Wan, Jian J; Wan, Cuihong C
Publication Date: 2021

Variant appearance in text: 225: A45N
PubMed Link: 34381774
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape.

Journal For Immunotherapy Of Cancer
Lu, Chunwan C; Liu, Zhuoqi Z; Klement, John D JD; Yang, Dafeng D; Merting, Alyssa D AD; Poschel, Dakota D; Albers, Thomas T; Waller, Jennifer L JL; Shi, Huidong H; Liu, Kebin K
Publication Date: 2021-07

Variant appearance in text: 225: A45N
PubMed Link: 34326167
Variant Present in the following documents:
  • jitc-2021-002624supp001.pdf
View BVdb publication page



Chromosomal copy number heterogeneity predicts survival rates across cancers.

Nature Communications
van Dijk, Erik E; van den Bosch, Tom T; Lenos, Kristiaan J KJ; El Makrini, Khalid K; Nijman, Lisanne E LE; van Essen, Hendrik F B HFB; Lansu, Nico N; Boekhout, Michiel M; Hageman, Joris H JH; Fitzgerald, Rebecca C RC; Punt, Cornelis J A CJA; Tuynman, Jurriaan B JB; Snippert, Hugo J G HJG; Kops, Geert J P L GJPL; Medema, Jan Paul JP; Ylstra, Bauke B; Vermeulen, Louis L; Miedema, Daniël M DM
Publication Date: 2021-05-27

Variant appearance in text: 225: A45N
PubMed Link: 34045449
Variant Present in the following documents:
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 58
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 59
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 66
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 62
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 63
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 61
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 65
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 60
  • 41467_2021_23384_MOESM4_ESM.xlsx, sheet 1
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 64
View BVdb publication page



The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.

Journal Of Experimental & Clinical Cancer Research : Cr
Qian, Weikun W; Chen, Ke K; Qin, Tao T; Xiao, Ying Y; Li, Jie J; Yue, Yangyang Y; Zhou, Cancan C; Ma, Jiguang J; Duan, Wanxing W; Lei, Jianjun J; Han, Liang L; Li, Li L; Shen, Xin X; Wu, Zheng Z; Ma, Qingyong Q; Wang, Zheng Z
Publication Date: 2021-01-09

Variant appearance in text: 225: A45N
PubMed Link: 33422093
Variant Present in the following documents:
  • 13046_2020_1823_MOESM2_ESM.xlsx, sheet 7
View BVdb publication page



Genomic analysis of the prognostic effect of tumor-associated neutrophil-related genes across 15 solid cancer types: an immune perspective.

Annals Of Translational Medicine
Hao, Yuying Y; Hu, Pingping P; Zhang, Jiandong J
Publication Date: 2020-11

Variant appearance in text: 225: A45N
PubMed Link: 33313252
Variant Present in the following documents:
  • atm-08-22-1507-supplementary.pdf
View BVdb publication page



A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.

Frontiers In Oncology
Kong, Lingming L; Liu, Peng P; Fei, Xiang X; Wu, Tianyu T; Wang, Zhongpeng Z; Zhang, Baohui B; Li, Jiatong J; Tan, Xiaodong X
Publication Date: 2020

Variant appearance in text: 225: A45N
PubMed Link: 32984053
Variant Present in the following documents:
  • Data_Sheet_2.xlsx, sheet 1
View BVdb publication page



Gene Signature and Identification of Clinical Trait-Related m6 A Regulators in Pancreatic Cancer.

Frontiers In Genetics
Hou, Jie J; Wang, Zhan Z; Li, Hong H; Zhang, Hongzhi H; Luo, Lan L
Publication Date: 2020

Variant appearance in text: 225: A45N
PubMed Link: 32754191
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi-omics data.

Molecular Oncology
Yang, Sheng S; Liu, Tong T; Liang, Geyu G
Publication Date: 2020-09

Variant appearance in text: 225: A45N
PubMed Link: 32580248
Variant Present in the following documents:
  • MOL2-14-2069-s002.xlsx, sheet 7
View BVdb publication page



BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice.

Nature Communications
Perkail, Stephanie S; Andricovich, Jaclyn J; Kai, Yan Y; Tzatsos, Alexandros A
Publication Date: 2020-06-15

Variant appearance in text: 225: A45N
PubMed Link: 32541668
Variant Present in the following documents:
  • 41467_2020_16589_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma.

Experimental And Therapeutic Medicine
Zhang, Wei W; Shang, Shuai S; Yang, Yingying Y; Lu, Peiyao P; Wang, Teng T; Cui, Xinyi X; Tang, Xuexi X
Publication Date: 2020-04

Variant appearance in text: 225: A45N
PubMed Link: 32256782
Variant Present in the following documents:
  • Supplementary_Data.pdf
View BVdb publication page



Lack of detectable neoantigen depletion signals in the untreated cancer genome.

Nature Genetics
Van den Eynden, Jimmy J; Jiménez-Sánchez, Alejandro A; Miller, Martin L ML; Larsson, Erik E
Publication Date: 2019-12

Variant appearance in text: 225: A45N
PubMed Link: 31768072
Variant Present in the following documents:
  • EMS84665-supplement-Suppl__table_2.xlsx, sheet 2
View BVdb publication page



Differential secretome of pancreatic cancer cells in serum-containing conditioned medium reveals CCT8 as a new biomarker of pancreatic cancer invasion and metastasis.

Cancer Cell International
Liu, Peng P; Kong, Lingming L; Jin, Haoyi H; Wu, Yunhao Y; Tan, Xiaodong X; Song, Bing B
Publication Date: 2019

Variant appearance in text: 225: A45N
PubMed Link: 31632196
Variant Present in the following documents:
  • 12935_2019_980_MOESM5_ESM.xlsx, sheet 4
  • 12935_2019_980_MOESM5_ESM.xlsx, sheet 3
  • 12935_2019_980_MOESM5_ESM.xlsx, sheet 2
  • 12935_2019_980_MOESM5_ESM.xlsx, sheet 5
View BVdb publication page



High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation.

Journal Of Cancer
Shen, Chao-Qin CQ; Yan, Ting-Ting TT; Liu, Wei W; Zhu, Xiao-Qiang XQ; Tian, Xiang-Long XL; Fu, Xue-Liang XL; Hua, Rong R; Zhang, Jun-Feng JF; Huo, Yan-Miao YM; Liu, De-Jun DJ; Yang, Jian-Yu JY; Sun, Yong-Wei YW; Fang, Jing-Yuan JY; Chen, Hao-Yan HY; Hong, Jie J
Publication Date: 2017

Variant appearance in text: 225: A45N
PubMed Link: 29158787
Variant Present in the following documents:
  • jcav08p3154s6.xlsx, sheet 1
View BVdb publication page



Mutation Clusters from Cancer Exome.

Genes
Kakushadze, Zura Z; Yu, Willie W
Publication Date: 2017-08-15

Variant appearance in text: 225: A45N
PubMed Link: 28809811
Variant Present in the following documents:
  • Main text
  • genes-08-00201.pdf
View BVdb publication page



Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate.

Elife
Juul, Malene M; Bertl, Johanna J; Guo, Qianyun Q; Nielsen, Morten Muhlig MM; Świtnicki, Michał M; Hornshøj, Henrik H; Madsen, Tobias T; Hobolth, Asger A; Pedersen, Jakob Skou JS
Publication Date: 2017-03-31

Variant appearance in text: 225: A45N
PubMed Link: 28362259
Variant Present in the following documents:
  • elife-21778-supp5.xlsx, sheet 5
View BVdb publication page