EGR1 c.160_161delinsTA ;(p.A54Y)

Variant ID: 5-137801610-GC-TA

NM_001964.2(EGR1):c.160_161delinsTA;(p.A54Y)

This variant was identified in 28 publications

View GRCh38 version.




Publications:


Deep learning model accurately classifies metastatic tumors from primary tumors based on mutational signatures.

Scientific Reports
Zheng, Weisheng W; Pu, Mengchen M; Li, Xiaorong X; Du, Zhaolan Z; Jin, Sutong S; Li, Xingshuai X; Zhou, Jielong J; Zhang, Yingsheng Y
Publication Date: 2023-05-30

Variant appearance in text: 225: A54Y
PubMed Link: 37253775
Variant Present in the following documents:
  • 41598_2023_35842_MOESM8_ESM.xlsx, sheet 3
  • 41598_2023_35842_MOESM8_ESM.xlsx, sheet 1
View BVdb publication page



Persistent mutation burden drives sustained anti-tumor immune responses.

Nature Medicine
Niknafs, Noushin N; Balan, Archana A; Cherry, Christopher C; Hummelink, Karlijn K; Monkhorst, Kim K; Shao, Xiaoshan M XM; Belcaid, Zineb Z; Marrone, Kristen A KA; Murray, Joseph J; Smith, Kellie N KN; Levy, Benjamin B; Feliciano, Josephine J; Hann, Christine L CL; Lam, Vincent V; Pardoll, Drew M DM; Karchin, Rachel R; Seiwert, Tanguy Y TY; Brahmer, Julie R JR; Forde, Patrick M PM; Velculescu, Victor E VE; Anagnostou, Valsamo V
Publication Date: 2023-01-26

Variant appearance in text: 225: A54Y
PubMed Link: 36702947
Variant Present in the following documents:
  • 41591_2022_2163_MOESM3_ESM.xlsx, sheet 3
  • 41591_2022_2163_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Increased expression of SYCP2 predicts poor prognosis in patients suffering from breast carcinoma.

Frontiers In Genetics
Zheng, Hongyan H; Guo, Xiaorong X; Li, Nan N; Qin, Luyao L; Li, Xiaoqing X; Lou, Ge G
Publication Date: 2022

Variant appearance in text: 225: A54Y
PubMed Link: 36159998
Variant Present in the following documents:
  • DataSheet7.xlsx, sheet 1
View BVdb publication page



Identification of cuproptosis-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognosis model in breast cancer.

Frontiers In Immunology
Li, Zhi Z; Zhang, Hua H; Wang, Xixi X; Wang, Qun Q; Xue, Jiapeng J; Shi, Yun Y; Wang, Minghua M; Wang, Geng G; Zhang, Jianquan J
Publication Date: 2022

Variant appearance in text: 225: A54Y
PubMed Link: 36059516
Variant Present in the following documents:
  • DataSheet_2.xlsx, sheet 6
View BVdb publication page



Pan-Cancer Analysis, Reveals COVID-19-Related BSG as a Novel Marker for Treatment and Identification of Multiple Human Cancers.

Frontiers In Cell And Developmental Biology
Huang, Tao T; He, Wei-Ying WY
Publication Date: 2022

Variant appearance in text: 225: A54Y
PubMed Link: 35646943
Variant Present in the following documents:
  • Table1.xlsx, sheet 5
View BVdb publication page



CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma.

Frontiers In Oncology
Qiao, Juanli J; Tian, Yuan Y; Cheng, Xiaojing X; Liu, Zhaojun Z; Zhou, Jing J; Gu, Liankun L; Zhang, Baozhen B; Zhang, Lianhai L; Ji, Jiafu J; Xing, Rui R; Deng, Dajun D
Publication Date: 2021

Variant appearance in text: 225: A54Y
PubMed Link: 35004325
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer.

Cancer Research
Xu, Ying Y; Ren, Wei W; Li, Qingjian Q; Duan, Chaohui C; Lin, Xiaorong X; Bi, Zhuofei Z; You, Kaiyun K; Hu, Qian Q; Xie, Ning N; Yu, Yunfang Y; Xu, Xiaoding X; Hu, Hai H; Yao, Herui H
Publication Date: 2022-02-15

Variant appearance in text: 225: A54Y
PubMed Link: 34965935
Variant Present in the following documents:
  • can-21-1446_supplementary_tables-1_suppst1.xlsx, sheet 3
View BVdb publication page



Significance of CD8+ T cell infiltration-related biomarkers and the corresponding prediction model for the prognosis of kidney renal clear cell carcinoma.

Aging
Tian, Yuan Y; Wei, Yumei Y; Liu, Hongmei H; Shang, Heli H; Xu, Yuedong Y; Wu, Tong T; Liu, Wei W; Huang, Alan A; Dang, Qi Q; Sun, Yuping Y
Publication Date: 2021-10-04

Variant appearance in text: 225: A54Y
PubMed Link: 34606472
Variant Present in the following documents:
  • aging-13-203584-s003.xlsx, sheet 1
  • aging-13-203584-s003.xlsx, sheet 3
View BVdb publication page



Synergistic apoptotic effect of miR-183-5p and Polo-Like kinase 1 inhibitor NMS-P937 in breast cancer cells.

Cell Death And Differentiation
Kudo, Masahisa M; Zalles, Nicole N; Distefano, Rosario R; Nigita, Giovanni G; Veneziano, Dario D; Gasparini, Pierluigi P; Croce, Carlo M CM
Publication Date: 2022-02

Variant appearance in text: 225: A54Y
PubMed Link: 34561554
Variant Present in the following documents:
  • 41418_2021_864_MOESM10_ESM.xlsx, sheet 14
  • 41418_2021_864_MOESM10_ESM.xlsx, sheet 10
View BVdb publication page



Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes.

Nature Communications
Redman-Rivera, Lindsay N LN; Shaver, Timothy M TM; Jin, Hailing H; Marshall, Clayton B CB; Schafer, Johanna M JM; Sheng, Quanhu Q; Hongo, Rachel A RA; Beckermann, Kathryn E KE; Wheeler, Ferrin C FC; Lehmann, Brian D BD; Pietenpol, Jennifer A JA
Publication Date: 2021-08-31

Variant appearance in text: 225: A54Y
PubMed Link: 34465782
Variant Present in the following documents:
  • 41467_2021_25359_MOESM5_ESM.xlsx, sheet 31
View BVdb publication page



Long noncoding RNA SNHG1 promotes TERT expression by sponging miR-18b-5p in breast cancer.

Cell & Bioscience
Kang, Yujuan Y; Wan, Lin L; Wang, Qin Q; Yin, Yanling Y; Liu, Jiena J; Liu, Lei L; Wu, Hao H; Zhang, Lei L; Zhang, Xin X; Xu, Shouping S; Pang, Da D
Publication Date: 2021-08-31

Variant appearance in text: 225: A54Y
PubMed Link: 34465388
Variant Present in the following documents:
  • 13578_2021_675_MOESM4_ESM.pdf
View BVdb publication page



CXCL10 potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors.

Theranostics
Shi, Zhiwen Z; Shen, Jianfeng J; Qiu, Junjun J; Zhao, Qingguo Q; Hua, Keqin K; Wang, Hongyan H
Publication Date: 2021

Variant appearance in text: 225: A54Y
PubMed Link: 34158843
Variant Present in the following documents:
  • thnov11p7175s1.xlsx, sheet 1
View BVdb publication page



Chromosomal copy number heterogeneity predicts survival rates across cancers.

Nature Communications
van Dijk, Erik E; van den Bosch, Tom T; Lenos, Kristiaan J KJ; El Makrini, Khalid K; Nijman, Lisanne E LE; van Essen, Hendrik F B HFB; Lansu, Nico N; Boekhout, Michiel M; Hageman, Joris H JH; Fitzgerald, Rebecca C RC; Punt, Cornelis J A CJA; Tuynman, Jurriaan B JB; Snippert, Hugo J G HJG; Kops, Geert J P L GJPL; Medema, Jan Paul JP; Ylstra, Bauke B; Vermeulen, Louis L; Miedema, Daniël M DM
Publication Date: 2021-05-27

Variant appearance in text: 225: A54Y
PubMed Link: 34045449
Variant Present in the following documents:
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 58
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 59
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 62
  • 41467_2021_23384_MOESM4_ESM.xlsx, sheet 1
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 60
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 66
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 63
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 65
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 61
  • 41467_2021_23384_MOESM7_ESM.xlsx, sheet 64
View BVdb publication page



Genomic analysis of the prognostic effect of tumor-associated neutrophil-related genes across 15 solid cancer types: an immune perspective.

Annals Of Translational Medicine
Hao, Yuying Y; Hu, Pingping P; Zhang, Jiandong J
Publication Date: 2020-11

Variant appearance in text: 225: A54Y
PubMed Link: 33313252
Variant Present in the following documents:
  • atm-08-22-1507-supplementary.pdf
View BVdb publication page



Roquin1 inhibits the proliferation of breast cancer cells by inducing G1/S cell cycle arrest via selectively destabilizing the mRNAs of cell cycle-promoting genes.

Journal Of Experimental & Clinical Cancer Research : Cr
Lu, Wenbao W; Zhou, Meicen M; Wang, Bing B; Liu, Xueting X; Li, Bingwei B
Publication Date: 2020-11-23

Variant appearance in text: 225: A54Y
PubMed Link: 33228782
Variant Present in the following documents:
  • 13046_2020_1766_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Wide-ranging analysis of survival-related alternative splicing events in invasive breast carcinoma.

Oncology Letters
Jia, Keren K; Wu, Yingcheng Y; Huang, Jing J; Chen, Jianing J; Wei, Huagen H; Wu, Huiqun H
Publication Date: 2020-08

Variant appearance in text: 225: A54Y
PubMed Link: 32724430
Variant Present in the following documents:
  • Supplementary_Data.pdf
View BVdb publication page



Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer.

Bmc Cancer
Soleimani Dodaran, Maryam M; Borgoni, Simone S; Sofyalı, Emre E; Verschure, Pernette J PJ; Wiemann, Stefan S; Moerland, Perry D PD; van Kampen, Antoine H C AHC
Publication Date: 2020-07-19

Variant appearance in text: 225: A54Y
PubMed Link: 32684154
Variant Present in the following documents:
  • 12885_2020_7100_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy.

Nature Communications
Zheng, Di-Wei DW; Gao, Fan F; Cheng, Qian Q; Bao, Peng P; Dong, Xue X; Fan, Jin-Xuan JX; Song, Wen W; Zeng, Xuan X; Cheng, Si-Xue SX; Zhang, Xian-Zheng XZ
Publication Date: 2020-04-24

Variant appearance in text: 225: A54Y
PubMed Link: 32332752
Variant Present in the following documents:
  • 41467_2020_15927_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



APOBEC3A is a prominent cytidine deaminase in breast cancer.

Plos Genetics
Cortez, Luis M LM; Brown, Amber L AL; Dennis, Madeline A MA; Collins, Christopher D CD; Brown, Alexander J AJ; Mitchell, Debra D; Mertz, Tony M TM; Roberts, Steven A SA
Publication Date: 2019-12

Variant appearance in text: 225: A54Y
PubMed Link: 31841499
Variant Present in the following documents:
  • pgen.1008545.s016.xlsx, sheet 7
View BVdb publication page



Lack of detectable neoantigen depletion signals in the untreated cancer genome.

Nature Genetics
Van den Eynden, Jimmy J; Jiménez-Sánchez, Alejandro A; Miller, Martin L ML; Larsson, Erik E
Publication Date: 2019-12

Variant appearance in text: 225: A54Y
PubMed Link: 31768072
Variant Present in the following documents:
  • EMS84665-supplement-Suppl__table_2.xlsx, sheet 2
View BVdb publication page



Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer.

Bmc Cancer
Zoppino, Felipe C M FCM; Guerrero-Gimenez, Martin E ME; Castro, Gisela N GN; Ciocca, Daniel R DR
Publication Date: 2018-06-28

Variant appearance in text: 225: A54Y
PubMed Link: 29954368
Variant Present in the following documents:
  • 12885_2018_4621_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.

Cell
Liu, Jianfang J; Lichtenberg, Tara T; Hoadley, Katherine A KA; Poisson, Laila M LM; Lazar, Alexander J AJ; Cherniack, Andrew D AD; Kovatich, Albert J AJ; Benz, Christopher C CC; Levine, Douglas A DA; Lee, Adrian V AV; Omberg, Larsson L; Wolf, Denise M DM; Shriver, Craig D CD; Thorsson, Vesteinn V; , ; Hu, Hai H
Publication Date: 2018-04-05

Variant appearance in text: 225: A54Y
PubMed Link: 29625055
Variant Present in the following documents:
  • NIHMS978596-supplement-1.xlsx, sheet 1
  • NIHMS978596-supplement-1.xlsx, sheet 3
View BVdb publication page



SETD7 is a prognosis predicting factor of breast cancer and regulates redox homeostasis.

Oncotarget
Huang, Run R; Li, Xiaolin X; Yu, Yang Y; Ma, Lisi L; Liu, Sixuan S; Zong, Xiangyun X; Zheng, Qi Q
Publication Date: 2017-11-07

Variant appearance in text: 225: A54Y
PubMed Link: 29212211
Variant Present in the following documents:
  • oncotarget-08-94080-s002.xls, sheet 1
View BVdb publication page



Mutation Clusters from Cancer Exome.

Genes
Kakushadze, Zura Z; Yu, Willie W
Publication Date: 2017-08-15

Variant appearance in text: 225: A54Y
PubMed Link: 28809811
Variant Present in the following documents:
  • Main text
  • genes-08-00201.pdf
View BVdb publication page



Long non-coding RNAs as prognostic markers in human breast cancer.

Oncotarget
Liu, Hairong H; Li, Juan J; Koirala, Pratirodh P; Ding, Xianfeng X; Chen, Binghai B; Wang, Yiheng Y; Wang, Zheng Z; Wang, Chuanxin C; Zhang, Xu X; Mo, Yin-Yuan YY
Publication Date: 2016-04-12

Variant appearance in text: 225: A54Y
PubMed Link: 26942882
Variant Present in the following documents:
  • oncotarget-07-20584-s005.xlsx, sheet 1
View BVdb publication page



Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies.

Oncotarget
Telonis, Aristeidis G AG; Loher, Phillipe P; Honda, Shozo S; Jing, Yi Y; Palazzo, Juan J; Kirino, Yohei Y; Rigoutsos, Isidore I
Publication Date: 2015-09-22

Variant appearance in text: 225: A54Y
PubMed Link: 26325506
Variant Present in the following documents:
  • oncotarget-06-24797-s002.xlsx, sheet 3
View BVdb publication page