The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides.
Cancer Immunology Research
Bedran, Georges G; Gasser, Hans-Christof HC; Weke, Kenneth K; Wang, Tongjie T; Bedran, Dominika D; Laird, Alexander A; Battail, Christophe C; Zanzotto, Fabio Massimo FM; Pesquita, Catia C; Axelson, Håkan H; Rajan, Ajitha A; Harrison, David J DJ; Palkowski, Aleksander A; Pawlik, Maciej M; Parys, Maciej M; O'Neill, J Robert JR; Brennan, Paul M PM; Symeonides, Stefan N SN; Goodlett, David R DR; Litchfield, Kevin K; Fahraeus, Robin R; Hupp, Ted R TR; Kote, Sachin S; Alfaro, Javier A JA
KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.
Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.
Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Risk Factors of Drug Resistance and the Potential Risk of HIV-1 Transmission of Patients with ART Virological Failure: A Population-Based Study in Sichuan, China.
Infection And Drug Resistance
Zhou, Chang C; Kang, Rui R; Liang, Shu S; Fei, Teng T; Li, Yiping Y; Su, Ling L; Li, Ling L; Ye, Li L; Zhang, Yan Y; Yuan, Dan D
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
Link, John O JO; Rhee, Martin S MS; Tse, Winston C WC; Zheng, Jim J; Somoza, John R JR; Rowe, William W; Begley, Rebecca R; Chiu, Anna A; Mulato, Andrew A; Hansen, Derek D; Singer, Eric E; Tsai, Luong K LK; Bam, Rujuta A RA; Chou, Chien-Hung CH; Canales, Eda E; Brizgys, Gediminas G; Zhang, Jennifer R JR; Li, Jiayao J; Graupe, Michael M; Morganelli, Philip P; Liu, Qi Q; Wu, Qiaoyin Q; Halcomb, Randall L RL; Saito, Roland D RD; Schroeder, Scott D SD; Lazerwith, Scott E SE; Bondy, Steven S; Jin, Debi D; Hung, Magdeleine M; Novikov, Nikolai N; Liu, Xiaohong X; Villaseñor, Armando G AG; Cannizzaro, Carina E CE; Hu, Eric Y EY; Anderson, Robert L RL; Appleby, Todd C TC; Lu, Bing B; Mwangi, Judy J; Liclican, Albert A; Niedziela-Majka, Anita A; Papalia, Giuseppe A GA; Wong, Melanie H MH; Leavitt, Stephanie A SA; Xu, Yili Y; Koditek, David D; Stepan, George J GJ; Yu, Helen H; Pagratis, Nikos N; Clancy, Sheila S; Ahmadyar, Shekeba S; Cai, Terrence Z TZ; Sellers, Scott S; Wolckenhauer, Scott A SA; Ling, John J; Callebaut, Christian C; Margot, Nicolas N; Ram, Renee R RR; Liu, Ya-Pei YP; Hyland, Rob R; Sinclair, Gary I GI; Ruane, Peter J PJ; Crofoot, Gordon E GE; McDonald, Cheryl K CK; Brainard, Diana M DM; Lad, Latesh L; Swaminathan, Swami S; Sundquist, Wesley I WI; Sakowicz, Roman R; Chester, Anne E AE; Lee, William E WE; Daar, Eric S ES; Yant, Stephen R SR; Cihlar, Tomas T
Prevalence and determinants of virological failure, genetic diversity and drug resistance among people living with HIV in a minority area in China: a population-based study.
Bmc Infectious Diseases
Yuan, Dan D; Liu, Meijing M; Jia, Peng P; Li, Yiping Y; Huang, Yuling Y; Ye, Li L; Api, Laze L; Chen, Maogang M; Yao, Liang L; Wang, Zixin Z; Liu, Honglu H; Liang, Shu S; Yang, Shujuan S
Analysis of HIV-1 diversity, primary drug resistance and transmission networks in Croatia.
Scientific Reports
Oroz, Maja M; Begovac, Josip J; Planinić, Ana A; Rokić, Filip F; Lunar, Maja M MM; Zorec, Tomaž Mark TM; Beluzić, Robert R; Korać, Petra P; Vugrek, Oliver O; Poljak, Mario M; Lepej, Snježana Židovec SŽ
Persistence of Human Immunodeficiency Virus-1 Drug Resistance Mutations in Proviral Deoxyribonucleic Acid After Virologic Failure of Efavirenz-Containing Antiretroviral Regimens.
Open Forum Infectious Diseases
De La Cruz, Justin J; Vardhanbhuti, Saran S; Sahoo, Malaya K MK; Rovner, Robert R; Bosch, Ronald J RJ; Manasa, Justen J; Katzenstein, David A DA; Pinsky, Benjamin A BA
Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring.
The Journal Of Antimicrobial Chemotherapy
Villa, Giovanni G; Phillips, Richard O RO; Smith, Colette C; Stockdale, Alexander J AJ; Ruggiero, Alessandra A; Beloukas, Apostolos A; Appiah, Lambert T LT; Chadwick, David D; Sarfo, Fred S FS; Geretti, Anna Maria AM
Raltegravir plus abacavir/lamivudine in virologically suppressed HIV-1-infected patients: 48-week results of the KIRAL study.
Plos One
Troya, Jesús J; Montejano, Rocio R; Ryan, Pablo P; Gómez, Cristina C; Matarranz, Mariano M; Cabello, Alfonso A; Vera, Francisco F; Sepúlveda, María Antonia MA; Santos, Ignacio I; Samperiz, Gloria G; Bachiller, Pablo P; Boix, Vicente V; Barrufet, Pilar P; Cervero, Miguel M; Sanz, José J; Solís, Javier J; Yllescas, María M; Valencia, Eulalia E; ,
Brazilian network for HIV Drug Resistance Surveillance (HIV-BresNet): a survey of treatment-naive individuals.
Journal Of The International Aids Society
Arruda, Monica B MB; Boullosa, Lídia T LT; Cardoso, Cynthia C CC; da Costa, Carolina M CM; Alves, Carlos Rb CR; de Lima, Shirlene Ts ST; Kaminski, Helena T HT; Aleixo, Agdemir W AW; Esposito, Ana Op AO; Cavalcanti, Ana Ms AM; Riedel, Maristela M; Couto-Fernandez, José C JC; Ferreira, Selma B SB; de Oliveira, Ivi Cm IC; Portal, Loreci E LE; Wolf, Hilda Hc HH; Fernandes, Sandra B SB; de M C Pardini, Maria I MI; Feiteiro, Manoel Vc MV; Tolentino, Fernanda M FM; Diaz, Ricardo S RS; Lopes, Giselle Isl GI; Francisco, Roberta Bl RB; Véras, Nazle Mc NM; Pires, Ana F AF; Franchini, Miriam M; Mesquita, Fábio F; Tanuri, Amilcar A; ,
Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes?
Aids Research And Therapy
Orrell, Catherine C; Cohen, Karen K; Leisegang, Rory R; Bangsberg, David R DR; Wood, Robin R; Maartens, Gary G
Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals after First-Line Antiretroviral Therapy Failure in South Africa.
Antimicrobial Agents And Chemotherapy
Penrose, Kerri J KJ; Wallis, Carole L CL; Brumme, Chanson J CJ; Hamanishi, Kristen A KA; Gordon, Kelley C KC; Viana, Raquel V RV; Harrigan, P Richard PR; Mellors, John W JW; Parikh, Urvi M UM
Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
Antimicrobial Agents And Chemotherapy
Tsiang, Manuel M; Jones, Gregg S GS; Goldsmith, Joshua J; Mulato, Andrew A; Hansen, Derek D; Kan, Elaine E; Tsai, Luong L; Bam, Rujuta A RA; Stepan, George G; Stray, Kirsten M KM; Niedziela-Majka, Anita A; Yant, Stephen R SR; Yu, Helen H; Kukolj, George G; Cihlar, Tomas T; Lazerwith, Scott E SE; White, Kirsten L KL; Jin, Haolun H
Smith, Steven J SJ; Pauly, Gary T GT; Akram, Aamir A; Melody, Kevin K; Rai, Ganesha G; Maloney, David J DJ; Ambrose, Zandrea Z; Thomas, Craig J CJ; Schneider, Joel T JT; Hughes, Stephen H SH
Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals.
Plos One
Blanco-Heredia, Juan J; Lecanda, Aarón A; Valenzuela-Ponce, Humberto H; Brander, Christian C; Ávila-Ríos, Santiago S; Reyes-Terán, Gustavo G
Population-based human immunodeficiency virus 1 drug resistance profiles among individuals who experienced virological failure to first-line antiretroviral therapy in Henan, China during 2010-2011.
Combination therapies, effectiveness, and adherence in patients with HIV infection: clinical utility of a single tablet of emtricitabine, rilpivirine, and tenofovir.
Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa.
Aids (London, England)
El-Khatib, Ziad Z; Ekstrom, Anna Mia AM; Ledwaba, Johanna J; Mohapi, Lerato L; Laher, Fatima F; Karstaedt, Alan A; Charalambous, Salome S; Petzold, Max M; Katzenstein, David D; Morris, Lynn L
The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity.
Antimicrobial Agents And Chemotherapy
Xu, Hong-Tao HT; Quan, Yudong Y; Schader, Susan M SM; Oliveira, Maureen M; Bar-Magen, Tamara T; Wainberg, Mark A MA
Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.
Nucleic Acids Research
Bauman, Joseph D JD; Das, Kalyan K; Ho, William C WC; Baweja, Mukta M; Himmel, Daniel M DM; Clark, Arthur D AD; Oren, Deena A DA; Boyer, Paul L PL; Hughes, Stephen H SH; Shatkin, Aaron J AJ; Arnold, Eddy E
Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.
Virology
Koval, Christine E CE; Dykes, Carrie C; Wang, Jiong J; Demeter, Lisa M LM
HIV-1 Protease and reverse-transcriptase mutations: correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance.
The Journal Of Infectious Diseases
Rhee, Soo-Yon SY; Fessel, W Jeffrey WJ; Zolopa, Andrew R AR; Hurley, Leo L; Liu, Tommy T; Taylor, Jonathan J; Nguyen, Dong Phuong DP; Slome, Sally S; Klein, Daniel D; Horberg, Michael M; Flamm, Jason J; Follansbee, Stephen S; Schapiro, Jonathan M JM; Shafer, Robert W RW