A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal.
Plos Computational Biology
Sun, James X JX; He, Yuting Y; Sanford, Eric E; Montesion, Meagan M; Frampton, Garrett M GM; Vignot, Stéphane S; Soria, Jean-Charles JC; Ross, Jeffrey S JS; Miller, Vincent A VA; Stephens, Phil J PJ; Lipson, Doron D; Yelensky, Roman R
Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies.
The Oncologist
Ali, Siraj M SM; Sanford, Eric M EM; Klempner, Samuel J SJ; Rubinson, Douglas A DA; Wang, Kai K; Palma, Norma A NA; Chmielecki, Juliann J; Yelensky, Roman R; Palmer, Gary A GA; Morosini, Deborah D; Lipson, Doron D; Catenacci, Daniel V DV; Braiteh, Fadi F; Erlich, Rachel R; Stephens, Philip J PJ; Ross, Jeffrey S JS; Ou, Sai-Hong Ignatius SH; Miller, Vincent A VA