JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21
Variant appearance in text: HMGCR: 1722+45A>G; rs3846662
Statins and cognition: Modifying factors and possible underlying mechanisms.
Frontiers In Aging Neuroscience
Jamshidnejad-Tosaramandani, Tahereh T; Kashanian, Soheila S; Al-Sabri, Mohamed H MH; Kročianová, Daniela D; Clemensson, Laura E LE; Gentreau, Mélissa M; Schiöth, Helgi B HB
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nature Genetics
Kerimov, Nurlan N; Hayhurst, James D JD; Peikova, Kateryna K; Manning, Jonathan R JR; Walter, Peter P; Kolberg, Liis L; Samoviča, Marija M; Sakthivel, Manoj Pandian MP; Kuzmin, Ivan I; Trevanion, Stephen J SJ; Burdett, Tony T; Jupp, Simon S; Parkinson, Helen H; Papatheodorou, Irene I; Yates, Andrew D AD; Zerbino, Daniel R DR; Alasoo, Kaur K
Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease.
Neuroimage. Clinical
Tremblay-Mercier, Jennifer J; Madjar, Cécile C; Das, Samir S; Pichet Binette, Alexa A; Dyke, Stephanie O M SOM; Étienne, Pierre P; Lafaille-Magnan, Marie-Elyse ME; Remz, Jordana J; Bellec, Pierre P; Louis Collins, D D; Natasha Rajah, M M; Bohbot, Veronique V; Leoutsakos, Jeannie-Marie JM; Iturria-Medina, Yasser Y; Kat, Justin J; Hoge, Richard D RD; Gauthier, Serge S; Tardif, Christine L CL; Mallar Chakravarty, M M; Poline, Jean-Baptiste JB; Rosa-Neto, Pedro P; Evans, Alan C AC; Villeneuve, Sylvia S; Poirier, Judes J; Breitner, John C S JCS; ,
Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study.
Npj Aging And Mechanisms Of Disease
Varma, Vijay R VR; Büşra Lüleci, H H; Oommen, Anup M AM; Varma, Sudhir S; Blackshear, Chad T CT; Griswold, Michael E ME; An, Yang Y; Roberts, Jackson A JA; O'Brien, Richard R; Pletnikova, Olga O; Troncoso, Juan C JC; Bennett, David A DA; Çakır, Tunahan T; Legido-Quigley, Cristina C; Thambisetty, Madhav M
Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain.
Frontiers In Molecular Neuroscience
Dupré, Nicolas N; Derambure, Céline C; Le Dieu-Lugon, Bérénice B; Hauchecorne, Michelle M; Detroussel, Yannick Y; Gonzalez, Bruno J BJ; Marret, Stéphane S; Leroux, Philippe P
Genetic drug target validation using Mendelian randomisation.
Nature Communications
Schmidt, Amand F AF; Finan, Chris C; Gordillo-Marañón, Maria M; Asselbergs, Folkert W FW; Freitag, Daniel F DF; Patel, Riyaz S RS; Tyl, Benoît B; Chopade, Sandesh S; Faraway, Rupert R; Zwierzyna, Magdalena M; Hingorani, Aroon D AD
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Significant association of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) rs3846662 and sirtuin 1 (SIRT1) rs7895833 and apolipoprotein E (APOE) hypermethylation with mild cognitive impairment (MCI).
Association study of rs3846662 with Alzheimer's disease in a population-based cohort: the Cache County Study.
Neurobiology Of Aging
Wright, Sage M SM; Jensen, Samantha L SL; Cockriel, Kristen L KL; Davis, Brian B; Tschanz, JoAnn T JT; Munger, Ronald G RG; Corcoran, Christopher D CD; Kauwe, John S K JSK
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
SNP rs688 within the low-density lipoprotein receptor (LDL-R) gene associates with HCV susceptibility.
Liver International : Official Journal Of The International Association For The Study Of The Liver
Steba, Gaby S GS; Koekkoek, Sylvie M SM; Tanck, Michael W T MWT; Vanhommerig, Joost W JW; van der Meer, Jan T M JTM; Kwa, David D; Brinkman, Kees K; Prins, Maria M; Berkhout, Ben B; Pollakis, Georgios G; Molenkamp, Richard R; Schinkel, Janke J; Paxton, William A WA; ,
A likely pathogenic variant putatively affecting splicing of PIGA identified in a multiple congenital anomalies hypotonia-seizures syndrome 2 (MCAHS2) family pedigree via whole-exome sequencing.
Relationship between Lipid Phenotypes, Overweight, Lipid Lowering Drug Response and KIF6 and HMG-CoA Genotypes in a Subset of the Brisighella Heart Study Population.
International Journal Of Molecular Sciences
Angelini, Sabrina S; Rosticci, Martina M; Massimo, Gianmichele G; Musti, Muriel M; Ravegnini, Gloria G; Consolini, Nicola N; Sammarini, Giulia G; D'Addato, Sergio S; Rizzoli, Elisabetta E; Botbayev, Dauren D; Borghi, Claudio C; Cantelli-Forti, Giorgio G; Cicero, Arrigo F AF; Hrelia, Patrizia P
Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials.
Alzheimer'S & Dementia : The Journal Of The Alzheimer'S Association
Weiner, Michael W MW; Veitch, Dallas P DP; Aisen, Paul S PS; Beckett, Laurel A LA; Cairns, Nigel J NJ; Green, Robert C RC; Harvey, Danielle D; Jack, Clifford R CR; Jagust, William W; Morris, John C JC; Petersen, Ronald C RC; Saykin, Andrew J AJ; Shaw, Leslie M LM; Toga, Arthur W AW; Trojanowski, John Q JQ; ,