POLK c.1295A>C ;(p.Y432S)

Variant ID: 5-74886204-A-C

NM_016218.2(POLK):c.1295A>C;(p.Y432S)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Mammalian DNA Polymerase Kappa Activity and Specificity.

Molecules (Basel, Switzerland)
Stern, Hannah R HR; Sefcikova, Jana J; Chaparro, Victoria E VE; Beuning, Penny J PJ
Publication Date: 2019-08-01

Variant appearance in text: POLK: Y432S; rs77612491
PubMed Link: 31374881
Variant Present in the following documents:
  • Main text
  • molecules-24-02805.pdf
View BVdb publication page



Characterization of Nine Cancer-Associated Variants in Human DNA Polymerase κ.

Chemical Research In Toxicology
Antczak, Nicole M NM; Walker, Alice R AR; Stern, Hannah R HR; Leddin, Emmett M EM; Palad, Carl C; Coulther, Timothy A TA; Swett, Rebecca J RJ; Cisneros, G Andrés GA; Beuning, Penny J PJ
Publication Date: 2018-08-20

Variant appearance in text: POLK: Y432S; rs77612491
PubMed Link: 30004685
Variant Present in the following documents:
  • Main text
View BVdb publication page



Biochemical characterization of eight genetic variants of human DNA polymerase κ involved in error-free bypass across bulky N(2)-guanyl DNA adducts.

Chemical Research In Toxicology
Song, Insil I; Kim, Eun-Jin EJ; Kim, In-Hyeok IH; Park, Eun-Mi EM; Lee, Kyung Eun KE; Shin, Joo-Ho JH; Guengerich, F Peter FP; Choi, Jeong-Yun JY
Publication Date: 2014-05-19

Variant appearance in text: POLK: 1295A>C; Y432S; rs77612491
PubMed Link: 24725253
Variant Present in the following documents:
  • Main text
View BVdb publication page