The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.
Frontiers In Pharmacology
Trompet, Stella S; Postmus, Iris I; Warren, Helen R HR; Noordam, Raymond R; Smit, Roelof A J RAJ; Theusch, Elizabeth E; Li, Xiaohui X; Arsenault, Benoit B; Chasman, Daniel I DI; Hitman, Graham A GA; Munroe, Patricia B PB; Rotter, Jerome I JI; Psaty, Bruce M BM; Caulfield, Mark J MJ; Krauss, Ron M RM; Cupples, Adrienne L AL; Jukema, Wouter J WJ
Epicardial Adipose Tissue: The Genetics Behind an Emerging Cardiovascular Risk Marker.
Clinical Medicine Insights. Cardiology
Sousa, João Adriano JA; Mendonça, Maria Isabel MI; Serrão, Marco M; Borges, Sofia S; Henriques, Eva E; Freitas, Sónia S; Tentem, Margarida M; Santos, Marina M; Freitas, Pedro P; Ferreira, António A; Guerra, Graça G; Drumond, António A; Palma Reis, Roberto R
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Importance of Thyroid Hormone level and Genetic Variations in Deiodinases for Patients after Acute Myocardial Infarction: A Longitudinal Observational Study.
Scientific Reports
Kazukauskiene, Nijole N; Skiriute, Daina D; Gustiene, Olivija O; Burkauskas, Julius J; Zaliunaite, Violeta V; Mickuviene, Narseta N; Brozaitiene, Julija J
Genetic risk scores for coronary artery disease and its traditional risk factors: Their role in the progression of coronary artery calcification-Results of the Heinz Nixdorf Recall study.
Plos One
Pechlivanis, Sonali S; Moebus, Susanne S; Lehmann, Nils N; Erbel, Raimund R; Mahabadi, Amir A AA; Hoffmann, Per P; Jöckel, Karl-Heinz KH; Nöthen, Markus M MM; Bachmann, Hagen S HS; ,
Metabolic and genetic profiling of young adults with and without a family history of premature coronary heart disease (MAGNETIC). Study design and methodology.
Archives Of Medical Science : Ams
Osadnik, Tadeusz T; Osadnik, Kamila K; Pawlas, Natalia N; Strzelczyk, Joanna J; Kasperczyk, Janusz J; Poloński, Lech L; Gąsior, Mariusz M
Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants.
Arquivos Brasileiros De Cardiologia
Pereira, Andreia A; Mendonça, Maria Isabel MI; Borges, Sofia S; Freitas, Sónia S; Henriques, Eva E; Rodrigues, Mariana M; Freitas, Ana Isabel AI; Sousa, Ana Célia AC; Brehm, António A; Reis, Roberto Palma Dos RPD
A clinical-genetic approach to assessing cardiovascular risk in patients with CKD.
Clinical Kidney Journal
Rodrigo, Emilio E; Pich, Sara S; Subirana, Isaac I; Fernandez-Fresnedo, Gema G; Barreda, Paloma P; Ferrer-Costa, Carles C; M de Francisco, Ángel Luis ÁL; Salas, Eduardo E; Elosua, Roberto R; Arias, Manuel M
Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study.
Frontiers In Cardiovascular Medicine
Knowles, Joshua W JW; Zarafshar, Shirin S; Pavlovic, Aleksandra A; Goldstein, Benjamin A BA; Tsai, Sandra S; Li, Jin J; McConnell, Michael V MV; Absher, Devin D; Ashley, Euan A EA; Kiernan, Michaela M; Ioannidis, John P A JPA; Assimes, Themistocles L TL
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
Plos Genetics
Byars, Sean G SG; Huang, Qin Qin QQ; Gray, Lesley-Ann LA; Bakshi, Andrew A; Ripatti, Samuli S; Abraham, Gad G; Stearns, Stephen C SC; Inouye, Michael M
The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle.
Circulation. Cardiovascular Genetics
Saddic, Louis A LA; Sigurdsson, Martin I MI; Chang, Tzuu-Wang TW; Mazaika, Erica E; Heydarpour, Mahyar M; Shernan, Stanton K SK; Seidman, Christine E CE; Seidman, Jon G JG; Aranki, Sary F SF; Body, Simon C SC; Muehlschlegel, Jochen D JD
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
PHACTR1 Gene Polymorphism Is Associated with Increased Risk of Developing Premature Coronary Artery Disease in Mexican Population.
International Journal Of Environmental Research And Public Health
Pérez-Hernández, Nonanzit N; Vargas-Alarcón, Gilberto G; Posadas-Sánchez, Rosalinda R; Martínez-Rodríguez, Nancy N; Tovilla-Zárate, Carlos Alfonso CA; Rodríguez-Cortés, Adrián Asael AA; Pérez-Méndez, Oscar O; Blachman-Braun, Ruben R; Rodríguez-Pérez, José Manuel JM
Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.
Data In Brief
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).
Atherosclerosis
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression.
Plos One
Kelloniemi, Annina A; Szabo, Zoltan Z; Serpi, Raisa R; Näpänkangas, Juha J; Ohukainen, Pauli P; Tenhunen, Olli O; Kaikkonen, Leena L; Koivisto, Elina E; Bagyura, Zsolt Z; Kerkelä, Risto R; Leosdottir, Margret M; Hedner, Thomas T; Melander, Olle O; Ruskoaho, Heikki H; Rysä, Jaana J
The rs12526453 Polymorphism in an Intron of the PHACTR1 Gene and Its Association with 5-Year Mortality of Patients with Myocardial Infarction.
Plos One
Szpakowicz, Anna A; Kiliszek, Marek M; Pepinski, Witold W; Waszkiewicz, Ewa E; Franaszczyk, Maria M; Skawronska, Malgorzata M; Ploski, Rafal R; Niemcunowicz-Janica, Anna A; Burzynska, Beata B; Tulacz, Dorota D; Maciejak, Agata A; Kaminski, Marcin Jakub MJ; Opolski, Grzegorz G; Musial, Wlodzimierz Jerzy WJ; Kaminski, Karol Adam KA
Myocardial Infarction-Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries.
Arteriosclerosis, Thrombosis, And Vascular Biology
Beaudoin, Mélissa M; Gupta, Rajat M RM; Won, Hong-Hee HH; Lo, Ken Sin KS; Do, Ron R; Henderson, Christopher A CA; Lavoie-St-Amour, Claire C; Langlois, Simon S; Rivas, Daniel D; Lehoux, Stephanie S; Kathiresan, Sekar S; Tardif, Jean-Claude JC; Musunuru, Kiran K; Lettre, Guillaume G
Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association.
Circulation. Cardiovascular Genetics
Musunuru, Kiran K; Hickey, Kathleen T KT; Al-Khatib, Sana M SM; Delles, Christian C; Fornage, Myriam M; Fox, Caroline S CS; Frazier, Lorraine L; Gelb, Bruce D BD; Herrington, David M DM; Lanfear, David E DE; Rosand, Jonathan J; ,
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach.
European Journal Of Human Genetics : Ejhg
Versmissen, Jorie J; Oosterveer, Daniëlla M DM; Yazdanpanah, Mojgan M; Dehghan, Abbas A; Hólm, Hilma H; Erdman, Jeanette J; Aulchenko, Yurii S YS; Thorleifsson, Gudmar G; Schunkert, Heribert H; Huijgen, Roeland R; Vongpromek, Ranitha R; Uitterlinden, André G AG; Defesche, Joep C JC; van Duijn, Cornelia M CM; Mulder, Monique M; Dadd, Tony T; Karlsson, Hróbjartur D HD; Ordovas, Jose J; Kindt, Iris I; Jarman, Amelia A; Hofman, Albert A; van Vark-van der Zee, Leonie L; Blommesteijn-Touw, Adriana C AC; Kwekkeboom, Jaap J; Liem, Anho H AH; van der Ouderaa, Frans J FJ; Calandra, Sebastiano S; Bertolini, Stefano S; Averna, Maurizio M; Langslet, Gisle G; Ose, Leiv L; Ros, Emilio E; Almagro, Fátima F; de Leeuw, Peter W PW; Civeira, Fernando F; Masana, Luis L; Pintó, Xavier X; Simoons, Maarten L ML; Schinkel, Arend F L AF; Green, Martin R MR; Zwinderman, Aeilko H AH; Johnson, Keith J KJ; Schaefer, Arne A; Neil, Andrew A; Witteman, Jacqueline C M JC; Humphries, Steve E SE; Kastelein, John J P JJ; Sijbrands, Eric J G EJ
Genetics of coronary artery calcification among African Americans, a meta-analysis.
Bmc Medical Genetics
Wojczynski, Mary K MK; Li, Mingyao M; Bielak, Lawrence F LF; Kerr, Kathleen F KF; Reiner, Alex P AP; Wong, Nathan D ND; Yanek, Lisa R LR; Qu, Liming L; White, Charles C CC; Lange, Leslie A LA; Ferguson, Jane F JF; He, Jing J; Young, Taylor T; Mosley, Thomas H TH; Smith, Jennifer A JA; Kral, Brian G BG; Guo, Xiuqing X; Wong, Quenna Q; Ganesh, Santhi K SK; Heckbert, Susan R SR; Griswold, Michael E ME; O'Leary, Daniel H DH; Budoff, Matthew M; Carr, J Jeffrey JJ; Taylor, Herman A HA; Bluemke, David A DA; Demissie, Serkalem S; Hwang, Shih-Jen SJ; Paltoo, Dina N DN; Polak, Joseph F JF; Psaty, Bruce M BM; Becker, Diane M DM; Province, Michael A MA; Post, Wendy S WS; O'Donnell, Christopher J CJ; Wilson, James G JG; Harris, Tamara B TB; Kavousi, Maryam M; Cupples, L Adrienne LA; Rotter, Jerome I JI; Fornage, Myriam M; Becker, Lewis C LC; Peyser, Patricia A PA; Borecki, Ingrid B IB; Reilly, Muredach P MP
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation
Olden, Matthias M; Teumer, Alexander A; Bochud, Murielle M; Pattaro, Cristian C; Köttgen, Anna A; Turner, Stephen T ST; Rettig, Rainer R; Chen, Ming-Huei MH; Dehghan, Abbas A; Bastardot, Francois F; Schmidt, Reinhold R; Vollenweider, Peter P; Schunkert, Heribert H; Reilly, Muredach P MP; Fornage, Myriam M; Launer, Lenore J LJ; Verwoert, Germaine C GC; Mitchell, Gary F GF; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Cheng, Ching-Yu CY; Sim, Xueling X; Siscovick, David S DS; Coresh, Josef J; Kao, W H Linda WH; Fox, Caroline S CS; O'Seaghdha, Conall M CM; ,
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
Bmc Medical Genetics
Pechlivanis, Sonali S; Mühleisen, Thomas W TW; Möhlenkamp, Stefan S; Schadendorf, Dirk D; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Hoffmann, Per P; Nöthen, Markus M MM; Scherag, André A; Moebus, Susanne S; ,
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Borden, William B WB; Bravata, Dawn M DM; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Magid, David D; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Nichol, Graham G; Paynter, Nina P NP; Schreiner, Pamela J PJ; Sorlie, Paul D PD; Stein, Joel J; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,