TNF c.581T>A ;(p.I194N)

Variant ID: 6-31545193-T-A

NM_000594.3(TNF):c.581T>A;(p.I194N)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Functional and Structural Impact of Deleterious Missense Single Nucleotide Polymorphisms in the NR3C1, CYP3A5, and TNF-α Genes: An In Silico Analysis.

Biomolecules
Ramayanam, Navakanth Raju NR; Manickam, Ranjani R; Mahalingam, Vijayakumar Thangavel VT; Goh, Khang Wen KW; Ardianto, Chrismawan C; Ganesan, Poovi P; Ming, Long Chiau LC; Ganesan, Rajanandh Muhasaparur RM
Publication Date: 2022-09-16

Variant appearance in text: TNF: I194N; rs11574936
PubMed Link: 36139147
Variant Present in the following documents:
  • Main text
  • biomolecules-12-01307.pdf
View BVdb publication page



Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation.

Cell Stem Cell
Merkle, Florian T FT; Ghosh, Sulagna S; Genovese, Giulio G; Handsaker, Robert E RE; Kashin, Seva S; Meyer, Daniel D; Karczewski, Konrad J KJ; O'Dushlaine, Colm C; Pato, Carlos C; Pato, Michele M; MacArthur, Daniel G DG; McCarroll, Steven A SA; Eggan, Kevin K
Publication Date: 2022-03-03

Variant appearance in text: TNF: 581T>A; Ile194Asn; rs11574936
PubMed Link: 35176222
Variant Present in the following documents:
  • mmc5.xlsx, sheet 3
  • mmc5.xlsx, sheet 1
View BVdb publication page



Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience
Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD
Publication Date: 2022-02

Variant appearance in text: TNF: I194N; rs11574936
PubMed Link: 35115730
Variant Present in the following documents:
  • 41593_2021_1006_MOESM4_ESM.xlsx, sheet 8
  • 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9
View BVdb publication page



Association of Tumor Necrosis Factor-Alpha-308 G/A and -238 G/A Polymorphism with Diabetic Retinopathy: A Systematic Review and Updated Meta-Analysis.

Ophthalmic Research
Gao, Wenna W; Zhu, Ruilin R; Yang, Liu L
Publication Date: 2021

Variant appearance in text: rs11574936
PubMed Link: 33279899
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs11574936
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



In silico analysis of single nucleotide polymorphism (SNP) in human TNF-α gene.

Meta Gene
Dabhi, Brijesh B; Mistry, Kinnari N KN
Publication Date: 2014-12

Variant appearance in text: TNF: I194N; rs11574936
PubMed Link: 25606441
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

Plos Genetics
Haiman, Christopher A CA; Han, Ying Y; Feng, Ye Y; Xia, Lucy L; Hsu, Chris C; Sheng, Xin X; Pooler, Loreall C LC; Patel, Yesha Y; Kolonel, Laurence N LN; Carter, Erin E; Park, Karen K; Le Marchand, Loic L; Van Den Berg, David D; Henderson, Brian E BE; Stram, Daniel O DO
Publication Date: 2013-03

Variant appearance in text: rs11574936
PubMed Link: 23555315
Variant Present in the following documents:
  • pgen.1003419.s009.xlsx, sheet 1
View BVdb publication page



A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults.

Malaria Journal
Randall, Louise M LM; Kenangalem, Enny E; Lampah, Daniel A DA; Tjitra, Emiliana E; Mwaikambo, Esther D ED; Handojo, Tjandra T; Piera, Kim A KA; Zhao, Zhen Z ZZ; de Labastida Rivera, Fabian F; Zhou, Yonghong Y; McSweeney, Karli M KM; Le, Lien L; Amante, Fiona H FH; Haque, Ashraful A; Stanley, Amanda C AC; Woodberry, Tonia T; Salwati, Ervi E; Granger, Donald L DL; Hobbs, Maurine R MR; Price, Ric N RN; Weinberg, J Brice JB; Montgomery, Grant W GW; Anstey, Nicholas M NM; Engwerda, Christian R CR
Publication Date: 2010-10-29

Variant appearance in text: rs11574936
PubMed Link: 21029472
Variant Present in the following documents:
  • Main text
  • 1475-2875-9-302.pdf
View BVdb publication page